More than 300 homologs were found in PanDaTox collection
for query gene Amir_6208 on replicon NC_013093
Organism: Actinosynnema mirum DSM 43827



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013093  Amir_6208  two component transcriptional regulator, winged helix family  100 
 
 
226 aa  437  9.999999999999999e-123  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_09580  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  63.56 
 
 
244 aa  282  3.0000000000000004e-75  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal  0.132168 
 
 
-
 
NC_009664  Krad_1230  two component transcriptional regulator, winged helix family  64.78 
 
 
254 aa  278  3e-74  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.211629  normal  0.177188 
 
 
-
 
NC_013174  Jden_1802  two component transcriptional regulator, winged helix family  63.84 
 
 
232 aa  278  4e-74  Jonesia denitrificans DSM 20603  Bacteria  normal  0.150286  normal 
 
 
-
 
NC_013172  Bfae_19400  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  63.44 
 
 
279 aa  273  1.0000000000000001e-72  Brachybacterium faecium DSM 4810  Bacteria  normal  0.0470356  n/a   
 
 
-
 
NC_013530  Xcel_2485  two component transcriptional regulator, winged helix family  63.84 
 
 
243 aa  273  1.0000000000000001e-72  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_013510  Tcur_1461  two component transcriptional regulator, winged helix family  65.47 
 
 
225 aa  268  2.9999999999999997e-71  Thermomonospora curvata DSM 43183  Bacteria  normal  0.616357  n/a   
 
 
-
 
NC_012669  Bcav_1276  two component transcriptional regulator, winged helix family  63.25 
 
 
242 aa  268  4e-71  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal  0.114994 
 
 
-
 
NC_013131  Caci_7562  two component transcriptional regulator, winged helix family  57.03 
 
 
273 aa  266  2.9999999999999995e-70  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.320599  normal 
 
 
-
 
NC_013595  Sros_1549  response regulator receiver protein  65 
 
 
241 aa  264  8e-70  Streptosporangium roseum DSM 43021  Bacteria  normal  0.0273908  normal 
 
 
-
 
NC_013947  Snas_5525  two component transcriptional regulator, winged helix family  67.58 
 
 
234 aa  261  8e-69  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.997238 
 
 
-
 
NC_014151  Cfla_1221  two component transcriptional regulator, winged helix family  62.22 
 
 
256 aa  256  2e-67  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.655279  normal 
 
 
-
 
NC_010816  BLD_0753  putative response regulator  56.19 
 
 
240 aa  247  1e-64  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_013721  HMPREF0424_0596  response regulator receiver domain protein  51.33 
 
 
250 aa  227  1e-58  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_011146  Gbem_2952  two component transcriptional regulator, winged helix family  50.45 
 
 
225 aa  191  6e-48  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2867  two component transcriptional regulator, winged helix family  46.7 
 
 
233 aa  191  1e-47  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_0588  two component transcriptional regulator, winged helix family  46.9 
 
 
226 aa  190  2e-47  Geobacter lovleyi SZ  Bacteria  normal  0.944339  n/a   
 
 
-
 
NC_012918  GM21_1271  two component transcriptional regulator, winged helix family  49.55 
 
 
225 aa  189  2.9999999999999997e-47  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_010424  Daud_1897  two component transcriptional regulator  47.98 
 
 
227 aa  188  5.999999999999999e-47  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.151466  n/a   
 
 
-
 
NC_009483  Gura_1572  two component transcriptional regulator  46.46 
 
 
225 aa  187  1e-46  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.000784208  n/a   
 
 
-
 
NC_008578  Acel_1449  two component transcriptional regulator  47.14 
 
 
246 aa  186  2e-46  Acidothermus cellulolyticus 11B  Bacteria  normal  0.566781  normal 
 
 
-
 
NC_008609  Ppro_3155  two component transcriptional regulator  45.61 
 
 
228 aa  187  2e-46  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  42.67 
 
 
235 aa  185  5e-46  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_002939  GSU1102  DNA-binding response regulator  46.9 
 
 
225 aa  185  6e-46  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_2513  two component transcriptional regulator, winged helix family  45.78 
 
 
225 aa  185  6e-46  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011899  Hore_21640  two component transcriptional regulator, winged helix family  44.14 
 
 
226 aa  184  7e-46  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000000176926  n/a   
 
 
-
 
NC_003909  BCE_4720  DNA-binding response regulator PhoP  41.1 
 
 
239 aa  184  1.0000000000000001e-45  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS4484  DNA-binding response regulator PhoP  41.1 
 
 
239 aa  183  1.0000000000000001e-45  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_4319  alkaline phosphatase synthesis response regulator  41.1 
 
 
239 aa  183  1.0000000000000001e-45  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4330  alkaline phosphatase synthesis response regulator  41.1 
 
 
239 aa  183  1.0000000000000001e-45  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_4833  DNA-binding response regulator PhoP  41.1 
 
 
239 aa  183  1.0000000000000001e-45  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.0982965  n/a   
 
 
-
 
NC_011773  BCAH820_4704  DNA-binding response regulator PhoP  41.1 
 
 
239 aa  183  1.0000000000000001e-45  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  0.00000000000000673192 
 
 
-
 
NC_011658  BCAH187_A4714  DNA-binding response regulator PhoP  41.1 
 
 
239 aa  183  1.0000000000000001e-45  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_013552  DhcVS_926  two-component system, OmpR family, response regulator  42.54 
 
 
227 aa  184  1.0000000000000001e-45  Dehalococcoides sp. VS  Bacteria  hitchhiker  0.00200634  n/a   
 
 
-
 
NC_007643  Rru_A0603  two component transcriptional regulator  46.32 
 
 
233 aa  183  2.0000000000000003e-45  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.0519325  n/a   
 
 
-
 
NC_010338  Caul_4546  two component transcriptional regulator  48.05 
 
 
230 aa  183  2.0000000000000003e-45  Caulobacter sp. K31  Bacteria  normal  normal  0.281853 
 
 
-
 
NC_011146  Gbem_1846  two component transcriptional regulator, winged helix family  45.33 
 
 
226 aa  183  2.0000000000000003e-45  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A4699  DNA-binding response regulator PhoP  40.68 
 
 
239 aa  182  3e-45  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B0539  DNA-binding response regulator PhoP  40.68 
 
 
239 aa  182  3e-45  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.000130788 
 
 
-
 
NC_010718  Nther_2903  two component transcriptional regulator, winged helix family  43.29 
 
 
234 aa  182  4.0000000000000006e-45  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal 
 
 
-
 
NC_009632  SaurJH1_1784  alkaline phosphatase synthesis transcriptional regulatory protein  41.81 
 
 
234 aa  182  5.0000000000000004e-45  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.561076  n/a   
 
 
-
 
NC_009487  SaurJH9_1750  two component transcriptional regulator  41.81 
 
 
234 aa  182  5.0000000000000004e-45  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_3274  two component transcriptional regulator  41.28 
 
 
238 aa  181  6e-45  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_2693  two component transcriptional regulator  46.46 
 
 
226 aa  181  7e-45  Geobacter metallireducens GS-15  Bacteria  normal  normal  0.575064 
 
 
-
 
NC_010184  BcerKBAB4_4419  two component transcriptional regulator  41.53 
 
 
239 aa  181  7e-45  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_009675  Anae109_0415  two component transcriptional regulator  48.46 
 
 
231 aa  181  7e-45  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  normal  0.777838 
 
 
-
 
NC_009012  Cthe_2333  two component transcriptional regulator  42.11 
 
 
232 aa  181  7e-45  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_0588  two component transcriptional regulator  41.59 
 
 
227 aa  180  1e-44  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000451147  n/a   
 
 
-
 
NC_010581  Bind_3302  two component transcriptional regulator  42.92 
 
 
230 aa  181  1e-44  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.288231  normal  0.346827 
 
 
-
 
NC_013521  Sked_09340  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  44.34 
 
 
223 aa  180  2e-44  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.217912  normal  0.763127 
 
 
-
 
NC_011891  A2cp1_4151  two component transcriptional regulator, winged helix family  48.02 
 
 
230 aa  179  4e-44  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_011145  AnaeK_4125  two component transcriptional regulator, winged helix family  48.02 
 
 
230 aa  178  4.999999999999999e-44  Anaeromyxobacter sp. K  Bacteria  normal  0.125271  n/a   
 
 
-
 
NC_008576  Mmc1_1491  two component transcriptional regulator  45.58 
 
 
236 aa  178  4.999999999999999e-44  Magnetococcus sp. MC-1  Bacteria  normal  decreased coverage  0.00391258 
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  40.77 
 
 
234 aa  178  5.999999999999999e-44  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_010581  Bind_3413  two component transcriptional regulator  48.07 
 
 
252 aa  178  7e-44  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal  0.427436 
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  41.81 
 
 
239 aa  178  8e-44  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_013205  Aaci_1728  two component transcriptional regulator, winged helix family  43.61 
 
 
233 aa  178  8e-44  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  41.81 
 
 
239 aa  178  8e-44  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_003909  BCE_5615  DNA-binding response regulator YycF  43.16 
 
 
235 aa  177  1e-43  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_013739  Cwoe_4508  two component transcriptional regulator, winged helix family  44.93 
 
 
231 aa  177  1e-43  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_005945  BAS5319  DNA-binding response regulator YycF  43.16 
 
 
235 aa  177  1e-43  Bacillus anthracis str. Sterne  Bacteria  normal  0.169223  n/a   
 
 
-
 
NC_011658  BCAH187_A5650  DNA-binding response regulator YycF  43.16 
 
 
235 aa  177  1e-43  Bacillus cereus AH187  Bacteria  hitchhiker  0.00563499  n/a   
 
 
-
 
NC_005957  BT9727_5147  response regulator  43.16 
 
 
235 aa  177  1e-43  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.00168683  n/a   
 
 
-
 
NC_010803  Clim_0772  two component transcriptional regulator, winged helix family  42.92 
 
 
233 aa  177  1e-43  Chlorobium limicola DSM 245  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK5163  response regulator  43.16 
 
 
235 aa  177  1e-43  Bacillus cereus E33L  Bacteria  hitchhiker  0.00196509  n/a   
 
 
-
 
NC_009767  Rcas_0353  two component transcriptional regulator  48.91 
 
 
230 aa  177  1e-43  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.683455 
 
 
-
 
NC_011773  BCAH820_5572  DNA-binding response regulator YycF  43.16 
 
 
235 aa  177  1e-43  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  1.81316e-29 
 
 
-
 
NC_007530  GBAA_5715  DNA-binding response regulator YycF  43.16 
 
 
235 aa  177  1e-43  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.656882  n/a   
 
 
-
 
NC_007760  Adeh_4009  two component transcriptional regulator  47.58 
 
 
230 aa  177  1e-43  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  decreased coverage  0.00751412  n/a   
 
 
-
 
NC_011831  Cagg_0243  two component transcriptional regulator, winged helix family  48.21 
 
 
235 aa  177  1e-43  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.0646165  normal 
 
 
-
 
NC_012803  Mlut_18360  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  50 
 
 
239 aa  176  2e-43  Micrococcus luteus NCTC 2665  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_4006  two component transcriptional regulator  43.16 
 
 
235 aa  176  2e-43  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.010356  n/a   
 
 
-
 
NC_011059  Paes_0769  two component transcriptional regulator, winged helix family  45.18 
 
 
236 aa  177  2e-43  Prosthecochloris aestuarii DSM 271  Bacteria  normal  normal 
 
 
-
 
NC_011772  BCG9842_B5346  DNA-binding response regulator YycF  43.16 
 
 
235 aa  176  2e-43  Bacillus cereus G9842  Bacteria  hitchhiker  0.000000234523  hitchhiker  0.00000000000323141 
 
 
-
 
NC_010184  BcerKBAB4_5259  two component transcriptional regulator  43.16 
 
 
235 aa  176  2e-43  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.000559572  n/a   
 
 
-
 
NC_011725  BCB4264_A5589  DNA-binding response regulator YycF  43.16 
 
 
235 aa  176  2e-43  Bacillus cereus B4264  Bacteria  normal  0.0469644  n/a   
 
 
-
 
NC_009511  Swit_3577  two component transcriptional regulator  48.9 
 
 
232 aa  176  3e-43  Sphingomonas wittichii RW1  Bacteria  normal  normal  0.70324 
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  43.11 
 
 
232 aa  176  3e-43  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_1865  two component transcriptional regulator, winged helix family  43.61 
 
 
226 aa  176  3e-43  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_009455  DehaBAV1_0937  two component transcriptional regulator  42.79 
 
 
227 aa  176  3e-43  Dehalococcoides sp. BAV1  Bacteria  normal  0.834094  n/a   
 
 
-
 
NC_011126  HY04AAS1_1151  two component transcriptional regulator, winged helix family  39.56 
 
 
225 aa  175  4e-43  Hydrogenobaculum sp. Y04AAS1  Bacteria  normal  n/a   
 
 
-
 
NC_008262  CPR_2497  DNA-binding response regulator  41.59 
 
 
228 aa  176  4e-43  Clostridium perfringens SM101  Bacteria  normal  n/a   
 
 
-
 
NC_007333  Tfu_0257  response regulator receiver  44.89 
 
 
241 aa  175  5e-43  Thermobifida fusca YX  Bacteria  normal  0.926332  n/a   
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  45.09 
 
 
229 aa  175  5e-43  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_008148  Rxyl_2983  two component transcriptional regulator  44.69 
 
 
228 aa  175  5e-43  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_3695  response regulator receiver  44.2 
 
 
236 aa  175  5e-43  Nocardioides sp. JS614  Bacteria  normal  0.795948  n/a   
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  40.44 
 
 
223 aa  175  5e-43  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_013595  Sros_0132  response regulator receiver protein  47.37 
 
 
231 aa  174  8e-43  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_007519  Dde_2387  two component transcriptional regulator  47.3 
 
 
229 aa  174  8e-43  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  hitchhiker  0.00115026  n/a   
 
 
-
 
NC_013385  Adeg_1028  two component transcriptional regulator, winged helix family  47.11 
 
 
237 aa  174  9.999999999999999e-43  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_1333  response regulator receiver protein  48 
 
 
222 aa  173  9.999999999999999e-43  Streptosporangium roseum DSM 43021  Bacteria  normal  0.40527  normal  0.1595 
 
 
-
 
NC_008347  Mmar10_0483  two component transcriptional regulator  46.32 
 
 
229 aa  174  9.999999999999999e-43  Maricaulis maris MCS10  Bacteria  normal  0.342081  normal 
 
 
-
 
NC_009972  Haur_0804  two component transcriptional regulator  44.34 
 
 
236 aa  174  9.999999999999999e-43  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.324741  n/a   
 
 
-
 
NC_011898  Ccel_3394  two component transcriptional regulator, winged helix family  40.53 
 
 
230 aa  174  9.999999999999999e-43  Clostridium cellulolyticum H10  Bacteria  normal  0.103692  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  42.48 
 
 
235 aa  174  9.999999999999999e-43  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_010718  Nther_1220  two component transcriptional regulator, winged helix family  41.74 
 
 
233 aa  174  9.999999999999999e-43  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  hitchhiker  0.00991602 
 
 
-
 
NC_002976  SERP1256  alkaline phosphatase synthesis transcriptional regulatory protein PhoP  40.43 
 
 
236 aa  173  1.9999999999999998e-42  Staphylococcus epidermidis RP62A  Bacteria  normal  0.577358  n/a   
 
 
-
 
NC_010001  Cphy_3429  two component transcriptional regulator  37.89 
 
 
233 aa  173  1.9999999999999998e-42  Clostridium phytofermentans ISDg  Bacteria  normal  0.0608192  n/a   
 
 
-
 
NC_011831  Cagg_1181  two component transcriptional regulator, winged helix family  46.43 
 
 
234 aa  173  1.9999999999999998e-42  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.00335068 
 
 
-
 
NC_009012  Cthe_1288  two component transcriptional regulator  39.56 
 
 
228 aa  173  1.9999999999999998e-42  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000000128008  n/a   
 
 
-
 
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