169 homologs were found in PanDaTox collection
for query gene AFE_0502 on replicon NC_011761
Organism: Acidithiobacillus ferrooxidans ATCC 23270



Page 1 of 2    << first  < prev  1  2    next >  last >>   


Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011206  Lferr_0663  3-demethylubiquinone-9 3-methyltransferase  100 
 
 
141 aa  295  1e-79  Acidithiobacillus ferrooxidans ATCC 53993  Bacteria  normal  normal 
 
 
-
 
NC_011761  AFE_0502  hypothetical protein  100 
 
 
141 aa  295  1e-79  Acidithiobacillus ferrooxidans ATCC 23270  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_0848  3-demethylubiquinone-9 3-methyltransferase  83.33 
 
 
161 aa  173  9e-43  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.000000136676  n/a   
 
 
-
 
NC_008782  Ajs_2267  3-demethylubiquinone-9 3-methyltransferase  80.21 
 
 
150 aa  172  1.9999999999999998e-42  Acidovorax sp. JS42  Bacteria  normal  0.0386327  normal  0.842376 
 
 
-
 
NC_007348  Reut_B4637  3-demethylubiquinone-9 3-methyltransferase  82.29 
 
 
159 aa  171  3.9999999999999995e-42  Ralstonia eutropha JMP134  Bacteria  normal  0.874058  n/a   
 
 
-
 
NC_010803  Clim_0594  3-demethylubiquinone-9 3-methyltransferase  82.29 
 
 
161 aa  170  5e-42  Chlorobium limicola DSM 245  Bacteria  normal  0.382309  n/a   
 
 
-
 
NC_011992  Dtpsy_1607  3-demethylubiquinone-9 3-methyltransferase  80.21 
 
 
161 aa  170  6.999999999999999e-42  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU2437  hypothetical protein  82.29 
 
 
161 aa  169  2e-41  Geobacter sulfurreducens PCA  Bacteria  hitchhiker  0.00410034  n/a   
 
 
-
 
NC_007517  Gmet_2483  3-demethylubiquinone-9 3-methyltransferase  83.33 
 
 
161 aa  169  2e-41  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.0000913491  normal 
 
 
-
 
NC_012857  Rpic12D_3981  3-demethylubiquinone-9 3-methyltransferase  80.21 
 
 
159 aa  167  5e-41  Ralstonia pickettii 12D  Bacteria  normal  normal 
 
 
-
 
NC_010678  Rpic_3867  3-demethylubiquinone-9 3-methyltransferase  80.21 
 
 
159 aa  167  5e-41  Ralstonia pickettii 12J  Bacteria  normal  normal  0.44427 
 
 
-
 
NC_003296  RS03882  hypothetical protein  79.17 
 
 
165 aa  164  2.9999999999999998e-40  Ralstonia solanacearum GMI1000  Bacteria  normal  0.279037  normal  0.767846 
 
 
-
 
NC_008825  Mpe_A1462  hypothetical protein  79.17 
 
 
159 aa  163  5.9999999999999996e-40  Methylibium petroleiphilum PM1  Bacteria  hitchhiker  0.00432951  normal  0.76996 
 
 
-
 
NC_009620  Smed_4431  3-demethylubiquinone-9 3-methyltransferase  80.21 
 
 
161 aa  163  5.9999999999999996e-40  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_007948  Bpro_1399  3-demethylubiquinone-9 3-methyltransferase  77.08 
 
 
165 aa  162  1.0000000000000001e-39  Polaromonas sp. JS666  Bacteria  normal  normal  0.3347 
 
 
-
 
NC_012792  Vapar_5736  3-demethylubiquinone-9 3-methyltransferase  78.12 
 
 
159 aa  160  4.0000000000000004e-39  Variovorax paradoxus S110  Bacteria  normal  n/a   
 
 
-
 
NC_012852  Rleg_6022  3-demethylubiquinone-9 3-methyltransferase  76.04 
 
 
157 aa  160  8.000000000000001e-39  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_008781  Pnap_4028  3-demethylubiquinone-9 3-methyltransferase  73.96 
 
 
176 aa  159  1e-38  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal  0.636645 
 
 
-
 
NC_012850  Rleg_2549  3-demethylubiquinone-9 3-methyltransferase  78.12 
 
 
157 aa  158  2e-38  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_2295  3-demethylubiquinone-9 3-methyltransferase  77.89 
 
 
162 aa  158  2e-38  Geobacter sp. M21  Bacteria  n/a    normal  0.0311325 
 
 
-
 
NC_010814  Glov_1008  3-demethylubiquinone-9 3-methyltransferase  76.04 
 
 
161 aa  157  6e-38  Geobacter lovleyi SZ  Bacteria  normal  0.214378  n/a   
 
 
-
 
NC_007974  Rmet_3848  putative 3-demethylubiquinone-9 3-methyltransferase  75 
 
 
161 aa  156  8e-38  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.52304 
 
 
-
 
NC_011369  Rleg2_2242  3-demethylubiquinone-9 3-methyltransferase  77.08 
 
 
157 aa  156  1e-37  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_011071  Smal_2877  3-demethylubiquinone-9 3-methyltransferase  73.68 
 
 
164 aa  155  2e-37  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal 
 
 
-
 
NC_008048  Sala_0011  3-demethylubiquinone-9 3-methyltransferase  77.08 
 
 
167 aa  155  2e-37  Sphingopyxis alaskensis RB2256  Bacteria  normal  0.448662  normal  0.0489572 
 
 
-
 
NC_007406  Nwi_0688  3-demethylubiquinone-9 3-methyltransferase  77.08 
 
 
159 aa  154  3e-37  Nitrobacter winogradskyi Nb-255  Bacteria  normal  0.331587  normal 
 
 
-
 
NC_011891  A2cp1_3393  3-demethylubiquinone-9 3-methyltransferase  77.08 
 
 
157 aa  154  3e-37  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_1925  3-demethylubiquinone-9 3-methyltransferase  76.84 
 
 
162 aa  154  3e-37  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.00859157  n/a   
 
 
-
 
NC_008686  Pden_0500  3-demethylubiquinone-9 3-methyltransferase  75 
 
 
159 aa  153  9e-37  Paracoccus denitrificans PD1222  Bacteria  normal  normal 
 
 
-
 
NC_011145  AnaeK_3319  3-demethylubiquinone-9 3-methyltransferase  76.04 
 
 
157 aa  153  1e-36  Anaeromyxobacter sp. K  Bacteria  normal  0.850052  n/a   
 
 
-
 
NC_010510  Mrad2831_6218  3-demethylubiquinone-9 3-methyltransferase  69.79 
 
 
166 aa  152  1e-36  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.701967  normal  0.334092 
 
 
-
 
NC_009675  Anae109_3253  3-demethylubiquinone-9 3-methyltransferase  76.04 
 
 
157 aa  152  2e-36  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  normal 
 
 
-
 
NC_010501  PputW619_2371  3-demethylubiquinone-9 3-methyltransferase  73.96 
 
 
169 aa  152  2e-36  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_007614  Nmul_A2171  3-demethylubiquinone-9 3-methyltransferase  80 
 
 
178 aa  150  4e-36  Nitrosospira multiformis ATCC 25196  Bacteria  normal  n/a   
 
 
-
 
NC_010571  Oter_2255  3-demethylubiquinone-9 3-methyltransferase  73.96 
 
 
173 aa  150  5.9999999999999996e-36  Opitutus terrae PB90-1  Bacteria  normal  0.604126  normal  0.0160885 
 
 
-
 
NC_008254  Meso_1468  3-demethylubiquinone-9 3-methyltransferase  73.96 
 
 
179 aa  150  7e-36  Chelativorans sp. BNC1  Bacteria  normal  0.852155  n/a   
 
 
-
 
NC_007760  Adeh_3194  3-demethylubiquinone-9 3-methyltransferase  75 
 
 
157 aa  150  8e-36  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_010322  PputGB1_2287  3-demethylubiquinone-9 3-methyltransferase  72.92 
 
 
159 aa  149  1e-35  Pseudomonas putida GB-1  Bacteria  normal  0.719915  normal  0.308943 
 
 
-
 
NC_011892  Mnod_8264  3-demethylubiquinone-9 3-methyltransferase  73.96 
 
 
158 aa  147  4e-35  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.677958  n/a   
 
 
-
 
NC_002947  PP_3629  3-demethylubiquinone-9 3-methyltransferase  72.92 
 
 
159 aa  147  5e-35  Pseudomonas putida KT2440  Bacteria  normal  0.481282  normal 
 
 
-
 
NC_008009  Acid345_1669  3-demethylubiquinone-9 3-methyltransferase  71.88 
 
 
158 aa  147  5e-35  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_011892  Mnod_8415  3-demethylubiquinone-9 3-methyltransferase  72.92 
 
 
158 aa  147  6e-35  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_3648  3-demethylubiquinone-9 3-methyltransferase  73.96 
 
 
158 aa  146  7e-35  Methylobacterium sp. 4-46  Bacteria  normal  hitchhiker  0.00571731 
 
 
-
 
NC_007964  Nham_0783  3-demethylubiquinone-9 3-methyltransferase  72.92 
 
 
166 aa  146  8e-35  Nitrobacter hamburgensis X14  Bacteria  normal  n/a   
 
 
-
 
NC_008463  PA14_28960  hypothetical protein  71.88 
 
 
159 aa  146  1.0000000000000001e-34  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  0.295823  hitchhiker  0.0000347275 
 
 
-
 
NC_009485  BBta_2181  hypothetical protein  73.96 
 
 
159 aa  146  1.0000000000000001e-34  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_2104  3-demethylubiquinone-9 3-methyltransferase  72.92 
 
 
159 aa  145  2.0000000000000003e-34  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_010524  Lcho_2956  3-demethylubiquinone-9 3-methyltransferase  65.62 
 
 
159 aa  142  1e-33  Leptothrix cholodnii SP-6  Bacteria  n/a    normal 
 
 
-
 
NC_009656  PSPA7_4000  hypothetical protein  70.83 
 
 
159 aa  142  1e-33  Pseudomonas aeruginosa PA7  Bacteria  normal  0.656805  n/a   
 
 
-
 
NC_011666  Msil_2215  3-demethylubiquinone-9 3-methyltransferase  67.71 
 
 
159 aa  140  6e-33  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_007794  Saro_2888  3-demethylubiquinone-9 3-methyltransferase  66.67 
 
 
165 aa  139  1.9999999999999998e-32  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  0.577012  n/a   
 
 
-
 
NC_009429  Rsph17025_3630  hypothetical protein  65.62 
 
 
165 aa  138  3e-32  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  0.0256913  normal 
 
 
-
 
NC_011892  Mnod_8684  3-demethylubiquinone-9 3-methyltransferase  83.33 
 
 
143 aa  118  3e-26  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_009921  Franean1_4069  3-demethylubiquinone-9 3-methyltransferase  51.04 
 
 
158 aa  111  4.0000000000000004e-24  Frankia sp. EAN1pec  Bacteria  normal  0.0386051  normal 
 
 
-
 
NC_009719  Plav_3503  3-demethylubiquinone-9 3-methyltransferase  42.96 
 
 
156 aa  109  1.0000000000000001e-23  Parvibaculum lavamentivorans DS-1  Bacteria  normal  0.936272  normal  0.391713 
 
 
-
 
NC_013440  Hoch_4782  3-demethylubiquinone-9 3-methyltransferase  51.04 
 
 
163 aa  106  1e-22  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_010338  Caul_0726  3-demethylubiquinone-9 3-methyltransferase  42.06 
 
 
159 aa  106  1e-22  Caulobacter sp. K31  Bacteria  normal  0.958881  normal  0.827037 
 
 
-
 
NC_014151  Cfla_2499  3-demethylubiquinone-9 3-methyltransferase  44.34 
 
 
159 aa  105  2e-22  Cellulomonas flavigena DSM 20109  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_2166  3-demethylubiquinone-9 3-methyltransferase  49.48 
 
 
170 aa  104  4e-22  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_013757  Gobs_3284  3-demethylubiquinone-9 3-methyltransferase  48.96 
 
 
159 aa  103  8e-22  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.313137  n/a   
 
 
-
 
NC_007964  Nham_3519  3-demethylubiquinone-9 3-methyltransferase  38.41 
 
 
157 aa  101  3e-21  Nitrobacter hamburgensis X14  Bacteria  normal  0.194698  n/a   
 
 
-
 
NC_008541  Arth_2204  3-demethylubiquinone-9 3-methyltransferase  39.13 
 
 
158 aa  99.4  1e-20  Arthrobacter sp. FB24  Bacteria  hitchhiker  0.00390727  n/a   
 
 
-
 
NC_008009  Acid345_1451  3-demethylubiquinone-9 3-methyltransferase  47.37 
 
 
157 aa  99  2e-20  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.334172  normal 
 
 
-
 
NC_013037  Dfer_1329  3-demethylubiquinone-9 3-methyltransferase  43.69 
 
 
163 aa  98.6  2e-20  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.998989  normal  0.921915 
 
 
-
 
NC_010581  Bind_3228  3-demethylubiquinone-9 3-methyltransferase  50.54 
 
 
173 aa  97.8  4e-20  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_008726  Mvan_4607  3-demethylubiquinone-9 3-methyltransferase  45.13 
 
 
157 aa  97.1  7e-20  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.576518  normal 
 
 
-
 
NC_010681  Bphyt_1272  3-demethylubiquinone-9 3-methyltransferase  39.13 
 
 
157 aa  96.7  9e-20  Burkholderia phytofirmans PsJN  Bacteria  normal  normal  0.123176 
 
 
-
 
NC_007908  Rfer_4108  3-demethylubiquinone-9 3-methyltransferase  41.48 
 
 
160 aa  96.3  1e-19  Rhodoferax ferrireducens T118  Bacteria  normal  0.105651  n/a   
 
 
-
 
NC_011004  Rpal_4903  3-demethylubiquinone-9 3-methyltransferase  42.71 
 
 
159 aa  96.3  1e-19  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.517944  n/a   
 
 
-
 
NC_013172  Bfae_22400  hypothetical protein  46.6 
 
 
178 aa  95.5  2e-19  Brachybacterium faecium DSM 4810  Bacteria  normal  0.100085  n/a   
 
 
-
 
NC_012850  Rleg_2821  3-demethylubiquinone-9 3-methyltransferase  40.91 
 
 
158 aa  95.1  3e-19  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.30678 
 
 
-
 
NC_007404  Tbd_1049  hypothetical protein  37.06 
 
 
178 aa  94.4  5e-19  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  0.980196  normal  0.183068 
 
 
-
 
NC_008146  Mmcs_4089  3-demethylubiquinone-9 3-methyltransferase  50 
 
 
157 aa  94.4  5e-19  Mycobacterium sp. MCS  Bacteria  normal  0.0395485  n/a   
 
 
-
 
NC_008705  Mkms_4165  3-demethylubiquinone-9 3-methyltransferase  50 
 
 
157 aa  94.4  5e-19  Mycobacterium sp. KMS  Bacteria  normal  0.982524  normal 
 
 
-
 
NC_009077  Mjls_4319  3-demethylubiquinone-9 3-methyltransferase  50 
 
 
157 aa  94.4  5e-19  Mycobacterium sp. JLS  Bacteria  normal  normal  0.26374 
 
 
-
 
NC_009338  Mflv_2098  3-demethylubiquinone-9 3-methyltransferase  35.9 
 
 
157 aa  94  7e-19  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.0724824  normal  0.234443 
 
 
-
 
NC_013739  Cwoe_4234  3-demethylubiquinone-9 3-methyltransferase  36.23 
 
 
159 aa  93.6  9e-19  Conexibacter woesei DSM 14684  Bacteria  normal  normal  0.24428 
 
 
-
 
NC_009078  BURPS1106A_A1642  3-demethylubiquinone-9 3-methyltransferase family protein  41.13 
 
 
220 aa  93.6  9e-19  Burkholderia pseudomallei 1106a  Bacteria  normal  0.165905  n/a   
 
 
-
 
NC_012850  Rleg_2532  3-demethylubiquinone-9 3-methyltransferase  44.79 
 
 
159 aa  92.8  1e-18  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_006349  BMAA1066  hypothetical protein  41.13 
 
 
157 aa  92.4  2e-18  Burkholderia mallei ATCC 23344  Bacteria  normal  n/a   
 
 
-
 
NC_007777  Francci3_2914  3-demethylubiquinone-9 3-methyltransferase  35.29 
 
 
157 aa  92.4  2e-18  Frankia sp. CcI3  Bacteria  normal  0.269995  normal  0.303399 
 
 
-
 
NC_007951  Bxe_A3278  putative 3-demethylubiquinone-93- methyltransferase protein  39.86 
 
 
156 aa  92.4  2e-18  Burkholderia xenovorans LB400  Bacteria  normal  0.278374  normal  0.25029 
 
 
-
 
NC_008784  BMASAVP1_0056  3-demethylubiquinone-9 3-methyltransferase family protein  41.13 
 
 
157 aa  92.4  2e-18  Burkholderia mallei SAVP1  Bacteria  normal  n/a   
 
 
-
 
NC_008835  BMA10229_0362  3-demethylubiquinone-9 3-methyltransferase family protein  41.13 
 
 
157 aa  92.4  2e-18  Burkholderia mallei NCTC 10229  Bacteria  normal  n/a   
 
 
-
 
NC_009075  BURPS668_A1731  3-demethylubiquinone-9 3-methyltransferase family protein  41.13 
 
 
157 aa  92.4  2e-18  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_009079  BMA10247_A1223  3-demethylubiquinone-9 3-methyltransferase family protein  41.13 
 
 
157 aa  92.4  2e-18  Burkholderia mallei NCTC 10247  Bacteria  normal  0.0864274  n/a   
 
 
-
 
NC_013235  Namu_5222  3-demethylubiquinone-9 3-methyltransferase  47.62 
 
 
159 aa  91.7  3e-18  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
NC_007511  Bcep18194_B2104  3-demethylubiquinone-9 3-methyltransferase  42.11 
 
 
157 aa  92  3e-18  Burkholderia sp. 383  Bacteria  normal  normal  0.171281 
 
 
-
 
NC_010725  Mpop_5293  3-demethylubiquinone-9 3-methyltransferase  44.79 
 
 
163 aa  91.7  3e-18  Methylobacterium populi BJ001  Bacteria  normal  normal  0.405768 
 
 
-
 
NC_013947  Snas_0556  3-demethylubiquinone-9 3-methyltransferase  45.28 
 
 
157 aa  91.3  4e-18  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_008391  Bamb_3373  3-demethylubiquinone-9 3-methyltransferase  42.11 
 
 
157 aa  91.3  4e-18  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_007651  BTH_I3172  3-demethylubiquinone-9 3-methyltransferase  37.5 
 
 
166 aa  90.9  6e-18  Burkholderia thailandensis E264  Bacteria  normal  n/a   
 
 
-
 
NC_010086  Bmul_4601  3-demethylubiquinone-9 3-methyltransferase  41.01 
 
 
157 aa  90.5  8e-18  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_4751  3-demethylubiquinone-9 3-methyltransferase  44.79 
 
 
163 aa  90.1  8e-18  Methylobacterium extorquens PA1  Bacteria  normal  0.492463  normal 
 
 
-
 
NC_009832  Spro_2516  3-demethylubiquinone-9 3-methyltransferase  41.67 
 
 
156 aa  90.1  9e-18  Serratia proteamaculans 568  Bacteria  normal  normal  0.676243 
 
 
-
 
NC_007948  Bpro_2381  3-demethylubiquinone-9 3-methyltransferase  43.3 
 
 
165 aa  89.7  1e-17  Polaromonas sp. JS666  Bacteria  normal  normal  0.721078 
 
 
-
 
NC_010002  Daci_4027  3-demethylubiquinone-9 3-methyltransferase  33.57 
 
 
167 aa  89.7  1e-17  Delftia acidovorans SPH-1  Bacteria  normal  0.560567  normal  0.360128 
 
 
-
 
NC_008543  Bcen2424_3980  3-demethylubiquinone-9 3-methyltransferase  42.22 
 
 
157 aa  89  2e-17  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_010552  BamMC406_3875  3-demethylubiquinone-9 3-methyltransferase  50.57 
 
 
157 aa  89.4  2e-17  Burkholderia ambifaria MC40-6  Bacteria  normal  0.183559  normal 
 
 
-
 
NC_010515  Bcenmc03_3548  3-demethylubiquinone-9 3-methyltransferase  42.22 
 
 
157 aa  89  2e-17  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.0531078  normal 
 
 
-
 
Page 1 of 2    << first  < prev  1  2    next >  last >>