More than 300 homologs were found in PanDaTox collection
for query gene Tmel_1838 on replicon NC_009616
Organism: Thermosipho melanesiensis BI429



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009616  Tmel_1838  two component transcriptional regulator  100 
 
 
239 aa  472  1e-132  Thermosipho melanesiensis BI429  Bacteria  hitchhiker  0.00000194698  n/a   
 
 
-
 
NC_009718  Fnod_1490  two component transcriptional regulator  87.03 
 
 
239 aa  427  1e-119  Fervidobacterium nodosum Rt17-B1  Bacteria  unclonable  0.000000000120928  n/a   
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  79.5 
 
 
239 aa  397  1e-109  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  79.5 
 
 
239 aa  397  1e-109  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_010003  Pmob_0875  two component transcriptional regulator  67.36 
 
 
242 aa  333  1e-90  Petrotoga mobilis SJ95  Bacteria  decreased coverage  0.000486966  n/a   
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  52.59 
 
 
239 aa  245  4.9999999999999997e-64  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  50.43 
 
 
229 aa  242  3.9999999999999997e-63  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_011899  Hore_21640  two component transcriptional regulator, winged helix family  55.46 
 
 
226 aa  239  2e-62  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000000176926  n/a   
 
 
-
 
NC_009012  Cthe_2333  two component transcriptional regulator  51.32 
 
 
232 aa  239  2.9999999999999997e-62  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  52.17 
 
 
232 aa  238  5.999999999999999e-62  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_010424  Daud_1419  two component transcriptional regulator  51.3 
 
 
231 aa  237  1e-61  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.0720218  n/a   
 
 
-
 
NC_010184  BcerKBAB4_5259  two component transcriptional regulator  50.42 
 
 
235 aa  236  2e-61  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.000559572  n/a   
 
 
-
 
NC_011772  BCG9842_B5346  DNA-binding response regulator YycF  50.42 
 
 
235 aa  235  4e-61  Bacillus cereus G9842  Bacteria  hitchhiker  0.000000234523  hitchhiker  0.00000000000323141 
 
 
-
 
NC_009674  Bcer98_4006  two component transcriptional regulator  50.42 
 
 
235 aa  235  4e-61  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.010356  n/a   
 
 
-
 
NC_011725  BCB4264_A5589  DNA-binding response regulator YycF  50.42 
 
 
235 aa  235  4e-61  Bacillus cereus B4264  Bacteria  normal  0.0469644  n/a   
 
 
-
 
NC_003909  BCE_5615  DNA-binding response regulator YycF  50.42 
 
 
235 aa  235  6e-61  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_5572  DNA-binding response regulator YycF  50.42 
 
 
235 aa  235  6e-61  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  1.81316e-29 
 
 
-
 
NC_005945  BAS5319  DNA-binding response regulator YycF  50.42 
 
 
235 aa  235  6e-61  Bacillus anthracis str. Sterne  Bacteria  normal  0.169223  n/a   
 
 
-
 
NC_005957  BT9727_5147  response regulator  50.42 
 
 
235 aa  235  6e-61  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.00168683  n/a   
 
 
-
 
NC_006274  BCZK5163  response regulator  50.42 
 
 
235 aa  235  6e-61  Bacillus cereus E33L  Bacteria  hitchhiker  0.00196509  n/a   
 
 
-
 
NC_007530  GBAA_5715  DNA-binding response regulator YycF  50.42 
 
 
235 aa  235  6e-61  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.656882  n/a   
 
 
-
 
NC_011658  BCAH187_A5650  DNA-binding response regulator YycF  50.42 
 
 
235 aa  235  6e-61  Bacillus cereus AH187  Bacteria  hitchhiker  0.00563499  n/a   
 
 
-
 
NC_011898  Ccel_3394  two component transcriptional regulator, winged helix family  51.97 
 
 
230 aa  234  9e-61  Clostridium cellulolyticum H10  Bacteria  normal  0.103692  n/a   
 
 
-
 
NC_011898  Ccel_2106  two component transcriptional regulator, winged helix family  53.19 
 
 
238 aa  233  1.0000000000000001e-60  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_009513  Lreu_0019  two component transcriptional regulator  49.79 
 
 
235 aa  233  2.0000000000000002e-60  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2867  two component transcriptional regulator, winged helix family  51.29 
 
 
233 aa  231  7.000000000000001e-60  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_0080  two component transcriptional regulator, winged helix family  50 
 
 
230 aa  229  2e-59  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  47.7 
 
 
235 aa  229  2e-59  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  48.71 
 
 
235 aa  229  2e-59  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_009012  Cthe_1394  two component transcriptional regulator  49.57 
 
 
236 aa  229  3e-59  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000024965  n/a   
 
 
-
 
NC_012793  GWCH70_3409  two component transcriptional regulator, winged helix family  48.95 
 
 
236 aa  228  5e-59  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_4050  two component transcriptional regulator, winged helix family  53.95 
 
 
227 aa  228  5e-59  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00552008  n/a   
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  47.46 
 
 
234 aa  228  6e-59  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_013411  GYMC61_3538  two component transcriptional regulator, winged helix family  50 
 
 
237 aa  226  2e-58  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_010816  BLD_1073  putative response regulator  46.38 
 
 
234 aa  226  3e-58  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_1997  two component transcriptional regulator  54.11 
 
 
234 aa  224  8e-58  Thermoanaerobacter sp. X514  Bacteria  hitchhiker  0.000000742772  n/a   
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  47.39 
 
 
226 aa  223  2e-57  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_008531  LEUM_1950  DNA-binding response regulator  49.37 
 
 
235 aa  221  4.9999999999999996e-57  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  0.100456  n/a   
 
 
-
 
NC_002976  SERP2534  DNA-binding response regulator YycF  50.44 
 
 
233 aa  221  6e-57  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_1487  two component transcriptional regulator, winged helix family  49.35 
 
 
232 aa  221  6e-57  Anaerocellum thermophilum DSM 6725  Bacteria  normal  0.487145  n/a   
 
 
-
 
NC_009632  SaurJH1_0018  response regulator receiver  50.44 
 
 
233 aa  221  7e-57  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_008527  LACR_0444  DNA-binding response regulator  48.07 
 
 
233 aa  221  7e-57  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_0018  two component transcriptional regulator  50.44 
 
 
233 aa  221  7e-57  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  0.70243  n/a   
 
 
-
 
NC_008530  LGAS_0064  DNA-binding response regulator  48.31 
 
 
235 aa  221  8e-57  Lactobacillus gasseri ATCC 33323  Bacteria  normal  0.611294  normal 
 
 
-
 
NC_003909  BCE_4720  DNA-binding response regulator PhoP  46.64 
 
 
239 aa  220  9.999999999999999e-57  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_010001  Cphy_1954  two component transcriptional regulator  51.08 
 
 
229 aa  220  9.999999999999999e-57  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.000155813  n/a   
 
 
-
 
NC_013552  DhcVS_143  DNA-binding response regulator, two-component system, OmpR family  47.44 
 
 
256 aa  221  9.999999999999999e-57  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS4484  DNA-binding response regulator PhoP  46.64 
 
 
239 aa  220  1.9999999999999999e-56  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_4319  alkaline phosphatase synthesis response regulator  46.64 
 
 
239 aa  220  1.9999999999999999e-56  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_3274  two component transcriptional regulator  47.26 
 
 
238 aa  220  1.9999999999999999e-56  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4330  alkaline phosphatase synthesis response regulator  46.64 
 
 
239 aa  220  1.9999999999999999e-56  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_4704  DNA-binding response regulator PhoP  46.64 
 
 
239 aa  220  1.9999999999999999e-56  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  0.00000000000000673192 
 
 
-
 
NC_007530  GBAA_4833  DNA-binding response regulator PhoP  46.64 
 
 
239 aa  220  1.9999999999999999e-56  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.0982965  n/a   
 
 
-
 
NC_013159  Svir_02690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  44.3 
 
 
229 aa  219  1.9999999999999999e-56  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_008261  CPF_0623  DNA-binding response regulator  52.16 
 
 
231 aa  220  1.9999999999999999e-56  Clostridium perfringens ATCC 13124  Bacteria  hitchhiker  0.000212568  n/a   
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  48.25 
 
 
229 aa  219  1.9999999999999999e-56  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_011658  BCAH187_A4714  DNA-binding response regulator PhoP  46.64 
 
 
239 aa  220  1.9999999999999999e-56  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_008532  STER_1116  DNA-binding response regulator  50.21 
 
 
235 aa  219  3e-56  Streptococcus thermophilus LMD-9  Bacteria  normal  0.310768  n/a   
 
 
-
 
NC_011725  BCB4264_A4699  DNA-binding response regulator PhoP  46.67 
 
 
239 aa  219  3.9999999999999997e-56  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B0539  DNA-binding response regulator PhoP  46.67 
 
 
239 aa  219  3.9999999999999997e-56  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.000130788 
 
 
-
 
NC_013595  Sros_0961  response regulator receiver protein  46.58 
 
 
229 aa  218  5e-56  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_010184  BcerKBAB4_4419  two component transcriptional regulator  47.06 
 
 
239 aa  218  6e-56  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_0378  two component transcriptional regulator  45.65 
 
 
234 aa  218  7.999999999999999e-56  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  49.14 
 
 
231 aa  218  7.999999999999999e-56  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013172  Bfae_09290  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  47.37 
 
 
229 aa  218  8.999999999999998e-56  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_1288  two component transcriptional regulator  48.92 
 
 
228 aa  218  8.999999999999998e-56  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000000128008  n/a   
 
 
-
 
NC_013205  Aaci_2922  two component transcriptional regulator, winged helix family  49.34 
 
 
230 aa  217  1e-55  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.221617  n/a   
 
 
-
 
NC_013174  Jden_2083  two component transcriptional regulator, winged helix family  45.76 
 
 
237 aa  217  1e-55  Jonesia denitrificans DSM 20603  Bacteria  normal  0.873655  normal 
 
 
-
 
NC_002936  DET0135  DNA-binding response regulator  46.55 
 
 
230 aa  216  2e-55  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_013169  Ksed_03700  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  45.18 
 
 
226 aa  216  2.9999999999999998e-55  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal  0.132847 
 
 
-
 
NC_008262  CPR_0609  DNA-binding response regulator  52.79 
 
 
231 aa  216  2.9999999999999998e-55  Clostridium perfringens SM101  Bacteria  hitchhiker  0.0000282114  n/a   
 
 
-
 
NC_008148  Rxyl_2983  two component transcriptional regulator  47.39 
 
 
228 aa  215  4e-55  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_009921  Franean1_6145  two component transcriptional regulator  45.69 
 
 
228 aa  215  5e-55  Frankia sp. EAN1pec  Bacteria  normal  normal  0.788201 
 
 
-
 
NC_013739  Cwoe_5905  two component transcriptional regulator, winged helix family  45.22 
 
 
237 aa  214  7e-55  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_014210  Ndas_4322  two component transcriptional regulator, winged helix family  47.37 
 
 
231 aa  214  9.999999999999999e-55  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_8215  two component transcriptional regulator, winged helix family  47.37 
 
 
226 aa  214  9.999999999999999e-55  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_013757  Gobs_4602  two component transcriptional regulator, winged helix family  46.49 
 
 
226 aa  213  1.9999999999999998e-54  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_0940  two component transcriptional regulator, winged helix family  48.5 
 
 
237 aa  213  1.9999999999999998e-54  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.324642  n/a   
 
 
-
 
NC_008528  OEOE_0105  DNA-binding response regulator  49.13 
 
 
237 aa  213  1.9999999999999998e-54  Oenococcus oeni PSU-1  Bacteria  normal  n/a   
 
 
-
 
NC_009455  DehaBAV1_0235  two component transcriptional regulator  47.66 
 
 
230 aa  213  1.9999999999999998e-54  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_007333  Tfu_2910  response regulator receiver  47.37 
 
 
230 aa  212  2.9999999999999995e-54  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_013093  Amir_6749  two component transcriptional regulator, winged helix family  43.86 
 
 
226 aa  212  2.9999999999999995e-54  Actinosynnema mirum DSM 43827  Bacteria  normal  0.290774  n/a   
 
 
-
 
NC_011661  Dtur_1237  two component transcriptional regulator, winged helix family  47.62 
 
 
232 aa  212  3.9999999999999995e-54  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_013510  Tcur_0700  two component transcriptional regulator, winged helix family  46.93 
 
 
226 aa  211  5.999999999999999e-54  Thermomonospora curvata DSM 43183  Bacteria  normal  0.768939  n/a   
 
 
-
 
NC_013124  Afer_0200  two component transcriptional regulator, winged helix family  43.17 
 
 
242 aa  211  7.999999999999999e-54  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  0.0955644  n/a   
 
 
-
 
NC_013205  Aaci_2570  two component transcriptional regulator, winged helix family  47.23 
 
 
239 aa  210  1e-53  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_014248  Aazo_2741  winged helix family two component transcriptional regulator  46.84 
 
 
250 aa  210  1e-53  'Nostoc azollae' 0708  Bacteria  normal  0.0957275  n/a   
 
 
-
 
NC_008699  Noca_4046  response regulator receiver  46.05 
 
 
225 aa  210  1e-53  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_007777  Francci3_0471  two component transcriptional regulator  46.49 
 
 
226 aa  209  2e-53  Frankia sp. CcI3  Bacteria  normal  normal  0.734397 
 
 
-
 
NC_014158  Tpau_0654  two component transcriptional regulator, winged helix family  43.17 
 
 
229 aa  210  2e-53  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.200991  n/a   
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  48.05 
 
 
236 aa  209  3e-53  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  49.56 
 
 
223 aa  209  3e-53  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_008541  Arth_0724  two component transcriptional regulator  45.69 
 
 
226 aa  209  3e-53  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_0588  two component transcriptional regulator  46.78 
 
 
227 aa  209  4e-53  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000451147  n/a   
 
 
-
 
NC_007413  Ava_3369  two component transcriptional regulator  46.38 
 
 
250 aa  209  4e-53  Anabaena variabilis ATCC 29413  Bacteria  normal  0.881494  normal  0.845013 
 
 
-
 
NC_007948  Bpro_0543  two component transcriptional regulator  42.8 
 
 
241 aa  209  4e-53  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_013530  Xcel_2514  two component transcriptional regulator, winged helix family  44.64 
 
 
226 aa  209  4e-53  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.24701  n/a   
 
 
-
 
NC_008726  Mvan_0831  two component transcriptional regulator  43.42 
 
 
228 aa  209  4e-53  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.310785  normal 
 
 
-
 
NC_012791  Vapar_2988  two component transcriptional regulator, winged helix family  42.19 
 
 
242 aa  209  5e-53  Variovorax paradoxus S110  Bacteria  normal  0.410423  n/a   
 
 
-
 
NC_010002  Daci_3071  two component transcriptional regulator  41.1 
 
 
238 aa  208  5e-53  Delftia acidovorans SPH-1  Bacteria  decreased coverage  0.000985444  normal 
 
 
-
 
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