More than 300 homologs were found in PanDaTox collection
for query gene Tmel_0691 on replicon NC_009616
Organism: Thermosipho melanesiensis BI429



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009616  Tmel_0691  binding-protein-dependent transport systems inner membrane component  100 
 
 
295 aa  583  1e-166  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_20620  binding-protein-dependent transport systems inner membrane component  43.4 
 
 
299 aa  234  1.0000000000000001e-60  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_2200  binding-protein-dependent transport systems inner membrane component  42.42 
 
 
299 aa  232  6e-60  Thermoanaerobacter sp. X514  Bacteria  normal  0.426381  n/a   
 
 
-
 
NC_013525  Tter_0830  binding-protein-dependent transport systems inner membrane component  38.89 
 
 
309 aa  224  1e-57  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_013526  Tter_2000  binding-protein-dependent transport systems inner membrane component  40.61 
 
 
319 aa  221  9.999999999999999e-57  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2208  binding-protein-dependent transport systems inner membrane component  39.86 
 
 
306 aa  214  9.999999999999999e-55  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.739705  n/a   
 
 
-
 
NC_013501  Rmar_0359  binding-protein-dependent transport systems inner membrane component  38.23 
 
 
300 aa  213  2.9999999999999995e-54  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_4638  binding-protein dependent transport system inner membrane protein  38.78 
 
 
308 aa  210  2e-53  Anabaena variabilis ATCC 29413  Bacteria  hitchhiker  0.000000461706  normal  0.23331 
 
 
-
 
NC_014248  Aazo_4983  binding-protein-dependent transporter inner membrane protein  35.66 
 
 
310 aa  209  3e-53  'Nostoc azollae' 0708  Bacteria  normal  0.300856  n/a   
 
 
-
 
NC_007413  Ava_0461  binding-protein dependent transport system inner membrane protein  39.58 
 
 
301 aa  209  4e-53  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.0667876 
 
 
-
 
NC_013526  Tter_2615  binding-protein-dependent transport systems inner membrane component  44.44 
 
 
307 aa  209  6e-53  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.0000296099  n/a   
 
 
-
 
NC_012848  Rleg_4872  binding-protein-dependent transport systems inner membrane component  37.2 
 
 
310 aa  207  2e-52  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.181942  normal  0.51159 
 
 
-
 
NC_007604  Synpcc7942_0526  ABC-type sugar transport systems permease components-like  36.08 
 
 
293 aa  204  1e-51  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_2365  sugar ABC transporter, permease protein  36.59 
 
 
288 aa  204  2e-51  Streptosporangium roseum DSM 43021  Bacteria  normal  0.216835  normal 
 
 
-
 
NC_002977  MCA1942  sugar ABC transporter, permease protein  40.99 
 
 
287 aa  202  6e-51  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_2875  binding-protein-dependent transport systems inner membrane component  38.16 
 
 
318 aa  202  7e-51  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.847542  normal  0.0272583 
 
 
-
 
NC_011884  Cyan7425_3980  binding-protein-dependent transport systems inner membrane component  36.62 
 
 
299 aa  202  8e-51  Cyanothece sp. PCC 7425  Bacteria  normal  hitchhiker  0.00655631 
 
 
-
 
NC_013205  Aaci_2047  binding-protein-dependent transport systems inner membrane component  38.97 
 
 
294 aa  201  8e-51  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.550241  n/a   
 
 
-
 
NC_013235  Namu_3848  binding-protein-dependent transport systems inner membrane component  38.57 
 
 
320 aa  202  8e-51  Nakamurella multipartita DSM 44233  Bacteria  normal  0.0230008  normal  0.429544 
 
 
-
 
NC_012669  Bcav_0016  binding-protein-dependent transport systems inner membrane component  39.35 
 
 
311 aa  201  9.999999999999999e-51  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.17058  normal 
 
 
-
 
NC_010003  Pmob_0955  binding-protein-dependent transport systems inner membrane component  41.35 
 
 
291 aa  199  3e-50  Petrotoga mobilis SJ95  Bacteria  normal  0.0196347  n/a   
 
 
-
 
NC_013526  Tter_2316  binding-protein-dependent transport systems inner membrane component  40.21 
 
 
313 aa  199  3.9999999999999996e-50  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_0754  binding-protein-dependent transport systems inner membrane component  37.2 
 
 
324 aa  199  3.9999999999999996e-50  Thermoanaerobacter sp. X514  Bacteria  decreased coverage  0.000000204062  n/a   
 
 
-
 
NC_013526  Tter_2523  binding-protein-dependent transport systems inner membrane component  38.57 
 
 
309 aa  197  1.0000000000000001e-49  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.00000000325465  n/a   
 
 
-
 
NC_010003  Pmob_0524  binding-protein-dependent transport systems inner membrane component  38.03 
 
 
303 aa  195  8.000000000000001e-49  Petrotoga mobilis SJ95  Bacteria  normal  0.693678  n/a   
 
 
-
 
NC_012034  Athe_2375  binding-protein-dependent transport systems inner membrane component  40.21 
 
 
298 aa  194  1e-48  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0532  binding-protein-dependent transport systems inner membrane component  39.56 
 
 
311 aa  194  1e-48  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009523  RoseRS_2819  binding-protein-dependent transport systems inner membrane component  39.08 
 
 
315 aa  194  1e-48  Roseiflexus sp. RS-1  Bacteria  normal  0.0308401  normal 
 
 
-
 
NC_011661  Dtur_0382  binding-protein-dependent transport systems inner membrane component  40.22 
 
 
296 aa  194  1e-48  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_15550  binding-protein-dependent transport systems inner membrane component  43.32 
 
 
294 aa  193  3e-48  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_07100  carbohydrate ABC transporter membrane protein  39.02 
 
 
318 aa  193  3e-48  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.790586  normal 
 
 
-
 
NC_013205  Aaci_1216  binding-protein-dependent transport systems inner membrane component  37.01 
 
 
315 aa  193  3e-48  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  decreased coverage  0.00000228392  n/a   
 
 
-
 
NC_013526  Tter_2024  binding-protein-dependent transport systems inner membrane component  40.29 
 
 
303 aa  193  3e-48  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.000000249122  n/a   
 
 
-
 
NC_011831  Cagg_2266  binding-protein-dependent transport systems inner membrane component  39.25 
 
 
296 aa  192  7e-48  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.0000392628 
 
 
-
 
NC_012848  Rleg_5053  binding-protein-dependent transport systems inner membrane component  34.81 
 
 
318 aa  192  8e-48  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.0625824  normal 
 
 
-
 
NC_013161  Cyan8802_4298  binding-protein-dependent transport systems inner membrane component  38.87 
 
 
294 aa  192  8e-48  Cyanothece sp. PCC 8802  Bacteria  normal  normal  0.200183 
 
 
-
 
NC_011726  PCC8801_4236  binding-protein-dependent transport systems inner membrane component  38.87 
 
 
294 aa  192  8e-48  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013521  Sked_21160  carbohydrate ABC transporter membrane protein  39.15 
 
 
314 aa  191  1e-47  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.103465  normal  0.100515 
 
 
-
 
NC_008262  CPR_0477  ABC tranporter, permease protein  37.67 
 
 
315 aa  190  2e-47  Clostridium perfringens SM101  Bacteria  normal  n/a   
 
 
-
 
NC_008262  CPR_0905  transmembrane permease MsmF  37.93 
 
 
289 aa  191  2e-47  Clostridium perfringens SM101  Bacteria  normal  0.0122469  n/a   
 
 
-
 
NC_009767  Rcas_2545  binding-protein-dependent transport systems inner membrane component  38.03 
 
 
316 aa  191  2e-47  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.637107  normal  0.115222 
 
 
-
 
NC_012669  Bcav_2264  binding-protein-dependent transport systems inner membrane component  36.55 
 
 
307 aa  189  2.9999999999999997e-47  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.277747  normal 
 
 
-
 
NC_011981  Avi_7347  ABC transporter membrane spanning protein (sugar)  34.59 
 
 
320 aa  189  5e-47  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_013517  Sterm_4036  binding-protein-dependent transport systems inner membrane component  38.46 
 
 
291 aa  189  5.999999999999999e-47  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_20510  binding-protein-dependent transport systems inner membrane component  38.77 
 
 
290 aa  189  7e-47  Halothermothrix orenii H 168  Bacteria  normal  0.0790749  n/a   
 
 
-
 
NC_012669  Bcav_3573  binding-protein-dependent transport systems inner membrane component  39.01 
 
 
353 aa  188  7e-47  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.500594  normal 
 
 
-
 
NC_012034  Athe_0400  binding-protein-dependent transport systems inner membrane component  35.84 
 
 
295 aa  188  1e-46  Anaerocellum thermophilum DSM 6725  Bacteria  unclonable  0.000000000506379  n/a   
 
 
-
 
NC_013595  Sros_6585  lactose transport system (permease)  39.72 
 
 
306 aa  187  1e-46  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_013411  GYMC61_2730  binding-protein-dependent transport systems inner membrane component  40 
 
 
300 aa  187  1e-46  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_012848  Rleg_4750  binding-protein-dependent transport systems inner membrane component  35.51 
 
 
299 aa  187  2e-46  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.62916  normal  0.701692 
 
 
-
 
NC_011886  Achl_3567  binding-protein-dependent transport systems inner membrane component  36.61 
 
 
309 aa  187  2e-46  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_011368  Rleg2_5350  binding-protein-dependent transport systems inner membrane component  38.49 
 
 
308 aa  187  2e-46  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.84186  normal  0.48209 
 
 
-
 
NC_009972  Haur_1151  binding-protein-dependent transport systems inner membrane component  40.6 
 
 
314 aa  187  2e-46  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.59424  n/a   
 
 
-
 
NC_011368  Rleg2_5336  binding-protein-dependent transport systems inner membrane component  34.47 
 
 
318 aa  186  3e-46  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.949955  normal 
 
 
-
 
NC_013521  Sked_03080  permease component of ABC-type sugar transporter  40 
 
 
322 aa  187  3e-46  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.151535  normal 
 
 
-
 
NC_011831  Cagg_0728  binding-protein-dependent transport systems inner membrane component  38.57 
 
 
313 aa  186  4e-46  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.000239391  normal 
 
 
-
 
NC_011988  Avi_5581  ABC transporter membrane spanning protein (galacturonic acid)  41.13 
 
 
314 aa  186  4e-46  Agrobacterium vitis S4  Bacteria  normal  0.512211  n/a   
 
 
-
 
NC_012912  Dd1591_1969  binding-protein-dependent transport systems inner membrane component  37.88 
 
 
296 aa  186  5e-46  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_3640  binding-protein-dependent transport systems inner membrane component  37.67 
 
 
298 aa  186  5e-46  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_008048  Sala_1022  binding-protein-dependent transport systems inner membrane component  36.52 
 
 
294 aa  185  7e-46  Sphingopyxis alaskensis RB2256  Bacteria  normal  normal 
 
 
-
 
NC_010816  BLD_1549  MalF-type ABC sugar transport systems permease component  36.68 
 
 
317 aa  184  1.0000000000000001e-45  Bifidobacterium longum DJO10A  Bacteria  normal  0.649517  n/a   
 
 
-
 
NC_012880  Dd703_2034  binding-protein-dependent transport systems inner membrane component  37.88 
 
 
296 aa  184  1.0000000000000001e-45  Dickeya dadantii Ech703  Bacteria  normal  0.963086  n/a   
 
 
-
 
NC_009523  RoseRS_1357  binding-protein-dependent transport systems inner membrane component  36.71 
 
 
316 aa  184  1.0000000000000001e-45  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_012669  Bcav_2978  binding-protein-dependent transport systems inner membrane component  37.41 
 
 
289 aa  184  1.0000000000000001e-45  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_011661  Dtur_0377  binding-protein-dependent transport systems inner membrane component  38.05 
 
 
294 aa  183  2.0000000000000003e-45  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_012850  Rleg_4345  binding-protein-dependent transport systems inner membrane component  40.14 
 
 
319 aa  184  2.0000000000000003e-45  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  hitchhiker  0.0000915897 
 
 
-
 
NC_011884  Cyan7425_4082  binding-protein-dependent transport systems inner membrane component  36.81 
 
 
302 aa  184  2.0000000000000003e-45  Cyanothece sp. PCC 7425  Bacteria  normal  normal 
 
 
-
 
NC_013205  Aaci_0914  binding-protein-dependent transport systems inner membrane component  36.45 
 
 
310 aa  184  2.0000000000000003e-45  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_013421  Pecwa_2200  binding-protein-dependent transport systems inner membrane component  38.26 
 
 
296 aa  184  2.0000000000000003e-45  Pectobacterium wasabiae WPP163  Bacteria  normal  0.467118  n/a   
 
 
-
 
NC_012028  Hlac_2863  binding-protein-dependent transport systems inner membrane component  40.43 
 
 
356 aa  183  3e-45  Halorubrum lacusprofundi ATCC 49239  Archaea  n/a    n/a   
 
 
-
 
NC_012669  Bcav_1297  binding-protein-dependent transport systems inner membrane component  37.68 
 
 
279 aa  183  3e-45  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.983189  normal 
 
 
-
 
NC_012917  PC1_1907  binding-protein-dependent transport systems inner membrane component  38.26 
 
 
296 aa  183  3e-45  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.0961638  n/a   
 
 
-
 
NC_009523  RoseRS_2895  binding-protein-dependent transport systems inner membrane component  36.45 
 
 
316 aa  183  3e-45  Roseiflexus sp. RS-1  Bacteria  normal  0.0497455  normal 
 
 
-
 
NC_010001  Cphy_0290  binding-protein-dependent transport systems inner membrane component  40.47 
 
 
297 aa  183  3e-45  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_013517  Sterm_4049  binding-protein-dependent transport systems inner membrane component  37.59 
 
 
292 aa  182  4.0000000000000006e-45  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_011881  Achl_4622  binding-protein-dependent transport systems inner membrane component  38.75 
 
 
317 aa  183  4.0000000000000006e-45  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_013526  Tter_2041  binding-protein-dependent transport systems inner membrane component  38.85 
 
 
305 aa  183  4.0000000000000006e-45  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.00457854  n/a   
 
 
-
 
NC_007778  RPB_0176  binding-protein dependent transport system inner membrane protein  37.4 
 
 
314 aa  182  6e-45  Rhodopseudomonas palustris HaA2  Bacteria  normal  normal 
 
 
-
 
NC_011884  Cyan7425_0944  binding-protein-dependent transport systems inner membrane component  36.52 
 
 
290 aa  182  7e-45  Cyanothece sp. PCC 7425  Bacteria  normal  0.120711  normal  0.307929 
 
 
-
 
NC_014165  Tbis_2715  binding-protein-dependent transporter inner membrane component  30.97 
 
 
350 aa  182  7e-45  Thermobispora bispora DSM 43833  Bacteria  normal  0.392142  normal 
 
 
-
 
NC_010001  Cphy_3401  binding-protein-dependent transport systems inner membrane component  37.83 
 
 
305 aa  182  8.000000000000001e-45  Clostridium phytofermentans ISDg  Bacteria  normal  0.028536  n/a   
 
 
-
 
NC_013739  Cwoe_3982  binding-protein-dependent transport systems inner membrane component  37.76 
 
 
316 aa  181  1e-44  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_014210  Ndas_0559  binding-protein-dependent transport systems inner membrane component  35.59 
 
 
305 aa  181  1e-44  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_013526  Tter_2217  binding-protein-dependent transport systems inner membrane component  35.56 
 
 
305 aa  181  1e-44  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_011369  Rleg2_4016  binding-protein-dependent transport systems inner membrane component  40.14 
 
 
319 aa  181  1e-44  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_007958  RPD_3149  binding-protein-dependent transport systems inner membrane component  35.71 
 
 
315 aa  180  2e-44  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.0566553  normal  0.330059 
 
 
-
 
NC_013235  Namu_0513  binding-protein-dependent transport systems inner membrane component  37.92 
 
 
314 aa  181  2e-44  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
NC_013526  Tter_2573  binding-protein-dependent transport systems inner membrane component  37.11 
 
 
309 aa  181  2e-44  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_1728  binding-protein-dependent transport systems inner membrane component  37.79 
 
 
299 aa  179  2.9999999999999997e-44  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_012669  Bcav_3898  binding-protein-dependent transport systems inner membrane component  35.34 
 
 
324 aa  180  2.9999999999999997e-44  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_012669  Bcav_0647  binding-protein-dependent transport systems inner membrane component  35.31 
 
 
325 aa  179  4e-44  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_012852  Rleg_6113  binding-protein-dependent transport systems inner membrane component  38.04 
 
 
286 aa  179  4e-44  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.453278  normal 
 
 
-
 
NC_013947  Snas_2734  binding-protein-dependent transport systems inner membrane component  35.05 
 
 
308 aa  179  4.999999999999999e-44  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.172129  normal  0.124427 
 
 
-
 
NC_013172  Bfae_29410  carbohydrate ABC transporter membrane protein  38.99 
 
 
322 aa  179  4.999999999999999e-44  Brachybacterium faecium DSM 4810  Bacteria  normal  0.899558  n/a   
 
 
-
 
NC_010001  Cphy_1390  binding-protein-dependent transport systems inner membrane component  37.16 
 
 
308 aa  179  4.999999999999999e-44  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_009636  Smed_3328  binding-protein-dependent transport systems inner membrane component  39.85 
 
 
318 aa  179  5.999999999999999e-44  Sinorhizobium medicae WSM419  Bacteria  normal  0.670475  normal  0.953703 
 
 
-
 
NC_009654  Mmwyl1_0774  binding-protein-dependent transport systems inner membrane component  37.23 
 
 
293 aa  179  7e-44  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_010513  Xfasm12_1606  ABC transporter sugar permease  34.93 
 
 
293 aa  179  7e-44  Xylella fastidiosa M12  Bacteria  normal  n/a   
 
 
-
 
NC_010717  PXO_00881  ABC transporter sugar permease  35.96 
 
 
294 aa  178  8e-44  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.0244413  n/a   
 
 
-
 
NC_013172  Bfae_29330  permease component of ABC-type sugar transporter  36.86 
 
 
321 aa  178  8e-44  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
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