More than 300 homologs were found in PanDaTox collection
for query gene Rsph17025_2440 on replicon NC_009428
Organism: Rhodobacter sphaeroides ATCC 17025



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009428  Rsph17025_2440  phosphatidylethanolamine N-methyltransferase  100 
 
 
204 aa  412  1e-114  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  normal  0.330514 
 
 
-
 
NC_007493  RSP_0721  phosphatidylethanolamine N-methyltransferase / phosphatidyl-N-methylethanolamine N-methyltransferase  92.16 
 
 
204 aa  387  1e-107  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  0.635481  n/a   
 
 
-
 
NC_009049  Rsph17029_2376  phosphatidylethanolamine N-methyltransferase  92.16 
 
 
204 aa  387  1e-107  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  normal  0.282292 
 
 
-
 
NC_008688  Pden_4690  phosphatidylethanolamine N-methyltransferase  59.8 
 
 
206 aa  247  7e-65  Paracoccus denitrificans PD1222  Bacteria  normal  normal  0.179715 
 
 
-
 
NC_008043  TM1040_3086  phosphatidylethanolamine N-methyltransferase / phosphatidyl-N-methylethanolamine N-methyltransferase  52.94 
 
 
213 aa  221  4e-57  Ruegeria sp. TM1040  Bacteria  normal  normal 
 
 
-
 
NC_009952  Dshi_2712  putative phosphatidylethanolamine N-methyltransferase  52.22 
 
 
226 aa  216  2e-55  Dinoroseobacter shibae DFL 12  Bacteria  normal  0.870029  normal 
 
 
-
 
NC_009719  Plav_2189  phosphatidylethanolamine N-methyltransferase  49.25 
 
 
229 aa  203  2e-51  Parvibaculum lavamentivorans DS-1  Bacteria  normal  normal 
 
 
-
 
NC_002977  MCA3065  phosphatidylethanolamine N-methyltransferase  46.83 
 
 
216 aa  186  2e-46  Methylococcus capsulatus str. Bath  Bacteria  normal  0.627483  n/a   
 
 
-
 
NC_009484  Acry_2168  phosphatidylethanolamine N-methyltransferase  48.02 
 
 
237 aa  179  2e-44  Acidiphilium cryptum JF-5  Bacteria  normal  0.240799  n/a   
 
 
-
 
NC_007778  RPB_4115  phosphatidylethanolamine N-methyltransferase  44.55 
 
 
212 aa  176  2e-43  Rhodopseudomonas palustris HaA2  Bacteria  normal  normal 
 
 
-
 
NC_010505  Mrad2831_0345  phosphatidylethanolamine N-methyltransferase  44.93 
 
 
228 aa  175  4e-43  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.935966  normal 
 
 
-
 
NC_011004  Rpal_1497  Phosphatidylethanolamine N-methyltransferase  43.56 
 
 
212 aa  174  9.999999999999999e-43  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_011365  Gdia_0321  Phosphatidylethanolamine N-methyltransferase  44.61 
 
 
245 aa  173  9.999999999999999e-43  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  0.943946  normal  0.235665 
 
 
-
 
NC_010511  M446_2685  phosphatidylethanolamine N-methyltransferase  43.96 
 
 
229 aa  172  3.9999999999999995e-42  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.469648 
 
 
-
 
NC_007925  RPC_0988  phosphatidylethanolamine N-methyltransferase  45.1 
 
 
212 aa  172  3.9999999999999995e-42  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.387372  decreased coverage  0.00000591406 
 
 
-
 
NC_010172  Mext_4097  phosphatidylethanolamine N-methyltransferase  45.5 
 
 
218 aa  171  5e-42  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.116223 
 
 
-
 
NC_011757  Mchl_4465  Phosphatidylethanolamine N-methyltransferase  45.5 
 
 
218 aa  171  5e-42  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.174082  normal 
 
 
-
 
NC_011894  Mnod_4809  Methyltransferase type 11  43.48 
 
 
229 aa  171  5e-42  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.483616  n/a   
 
 
-
 
NC_007958  RPD_3961  phosphatidylethanolamine N-methyltransferase  42.86 
 
 
212 aa  171  5.999999999999999e-42  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_4578  Phosphatidylethanolamine N-methyltransferase  45 
 
 
218 aa  170  2e-41  Methylobacterium populi BJ001  Bacteria  normal  0.30493  normal  0.829265 
 
 
-
 
NC_011894  Mnod_6066  Methyltransferase type 11  43.22 
 
 
217 aa  169  3e-41  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.451332  n/a   
 
 
-
 
NC_009485  BBta_1882  phosphatidyl-N-methylethanolamine N-methyltransferase  41.87 
 
 
211 aa  168  6e-41  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_007484  Noc_0914  phosphatidylethanolamine N-methyltransferase  41.87 
 
 
255 aa  167  1e-40  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_007406  Nwi_0604  UbiE/COQ5 methyltransferase  42.36 
 
 
212 aa  166  2e-40  Nitrobacter winogradskyi Nb-255  Bacteria  normal  0.977459  normal 
 
 
-
 
NC_007964  Nham_0696  phosphatidylethanolamine N-methyltransferase  41.38 
 
 
212 aa  166  2e-40  Nitrobacter hamburgensis X14  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_5117  phosphatidylethanolamine N-methyltransferase  42.21 
 
 
217 aa  165  4e-40  Methylobacterium sp. 4-46  Bacteria  normal  0.013812  hitchhiker  0.00397391 
 
 
-
 
NC_009485  BBta_6211  phosphatidyl-N-methylethanolamine N-methyltransferase  43.2 
 
 
225 aa  162  2.0000000000000002e-39  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_006368  lpp2097  hypothetical protein  39.51 
 
 
207 aa  161  5.0000000000000005e-39  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_008789  Hhal_0826  methyltransferase type 11  40.39 
 
 
224 aa  161  8.000000000000001e-39  Halorhodospira halophila SL1  Bacteria  normal  0.457177  n/a   
 
 
-
 
NC_006369  lpl2086  hypothetical protein  38.54 
 
 
207 aa  158  4e-38  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_009720  Xaut_0403  phosphatidylethanolamine N-methyltransferase  41.06 
 
 
214 aa  156  2e-37  Xanthobacter autotrophicus Py2  Bacteria  normal  0.0306332  normal 
 
 
-
 
NC_008340  Mlg_0492  phosphatidyl-N-methylethanolamine N-methyltransferase / phosphatidylethanolamine N-methyltransferase  38.73 
 
 
232 aa  152  2e-36  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  normal  0.578084 
 
 
-
 
NC_010505  Mrad2831_5064  phosphatidylethanolamine N-methyltransferase  41.71 
 
 
217 aa  153  2e-36  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.152165 
 
 
-
 
NC_007406  Nwi_0696  UbiE/COQ5 methyltransferase  39.41 
 
 
229 aa  149  3e-35  Nitrobacter winogradskyi Nb-255  Bacteria  normal  normal  0.488377 
 
 
-
 
NC_007958  RPD_1629  phosphatidylethanolamine N-methyltransferase  43.56 
 
 
218 aa  149  3e-35  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.615509  normal  0.918656 
 
 
-
 
NC_011901  Tgr7_1009  Methyltransferase type 11  42.05 
 
 
218 aa  149  4e-35  Thioalkalivibrio sp. HL-EbGR7  Bacteria  hitchhiker  0.00745554  n/a   
 
 
-
 
NC_011666  Msil_1939  Phosphatidylethanolamine N-methyltransferase  38.61 
 
 
220 aa  149  4e-35  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_013889  TK90_0730  Phosphatidylethanolamine N-methyltransferase  41.67 
 
 
207 aa  148  6e-35  Thioalkalivibrio sp. K90mix  Bacteria  normal  normal 
 
 
-
 
NC_011004  Rpal_4492  Phosphatidylethanolamine N-methyltransferase  43.63 
 
 
218 aa  147  8e-35  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_007778  RPB_1620  phosphatidylethanolamine N-methyltransferase  43.07 
 
 
218 aa  146  2.0000000000000003e-34  Rhodopseudomonas palustris HaA2  Bacteria  normal  normal 
 
 
-
 
NC_007925  RPC_1444  phosphatidylethanolamine N-methyltransferase  42.08 
 
 
219 aa  144  7.0000000000000006e-34  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.0474733  normal 
 
 
-
 
NC_012850  Rleg_0964  Phosphatidylethanolamine N-methyltransferase  37.68 
 
 
217 aa  144  8.000000000000001e-34  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.417338  normal 
 
 
-
 
NC_011369  Rleg2_0843  Phosphatidylethanolamine N-methyltransferase  39.3 
 
 
217 aa  144  8.000000000000001e-34  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_010581  Bind_3036  phosphatidylethanolamine N-methyltransferase  39.02 
 
 
229 aa  142  4e-33  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.133888  normal 
 
 
-
 
NC_011206  Lferr_2360  Methyltransferase type 11  32 
 
 
201 aa  106  3e-22  Acidithiobacillus ferrooxidans ATCC 53993  Bacteria  normal  0.175254  hitchhiker  0.000000000902529 
 
 
-
 
NC_011761  AFE_2739  phosphatidylethanolamine N-methyltransferase, putative  32 
 
 
201 aa  106  3e-22  Acidithiobacillus ferrooxidans ATCC 23270  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_0018  phosphatidylethanolamine N-methyltransferase / phosphatidyl-N-methylethanolamine N-methyltransferase  40.65 
 
 
204 aa  105  4e-22  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.000241496  hitchhiker  0.00000138707 
 
 
-
 
NC_008726  Mvan_2948  methyltransferase type 11  39.24 
 
 
212 aa  103  1e-21  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.160502  normal  0.130465 
 
 
-
 
NC_011901  Tgr7_2723  Methyltransferase type 11  32.49 
 
 
200 aa  103  2e-21  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_3485  phosphatidylethanolamine N-methyltransferase / phosphatidyl-N-methylethanolamine N-methyltransferase  31 
 
 
197 aa  101  9e-21  Dechloromonas aromatica RCB  Bacteria  normal  normal  0.171708 
 
 
-
 
NC_008782  Ajs_2160  methyltransferase type 11  36.84 
 
 
236 aa  96.7  2e-19  Acidovorax sp. JS42  Bacteria  normal  0.264842  normal  0.115714 
 
 
-
 
NC_007355  Mbar_A0008  phosphatidyl-N-methylethanolamine N-methyltransferase / phosphatidylethanolamine N-methyltransferase  37.24 
 
 
199 aa  89.7  2e-17  Methanosarcina barkeri str. Fusaro  Archaea  normal  0.257422  normal  0.214675 
 
 
-
 
NC_014210  Ndas_3689  Methyltransferase type 11  35.29 
 
 
195 aa  89.4  3e-17  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal  0.342023 
 
 
-
 
NC_013422  Hneap_1280  Methyltransferase type 11  32.03 
 
 
204 aa  89.4  3e-17  Halothiobacillus neapolitanus c2  Bacteria  normal  n/a   
 
 
-
 
NC_007963  Csal_2810  phosphatidyl-N-methylethanolamine N-methyltransferase / phosphatidylethanolamine N-methyltransferase  35.14 
 
 
205 aa  89  4e-17  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_1709  Methyltransferase type 11  36.2 
 
 
206 aa  87.4  1e-16  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.775489  normal  0.171516 
 
 
-
 
NC_011729  PCC7424_0288  Methyltransferase type 11  33.11 
 
 
215 aa  84.7  9e-16  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_013501  Rmar_1381  Methyltransferase type 11  39.57 
 
 
225 aa  84  0.000000000000001  Rhodothermus marinus DSM 4252  Bacteria  normal  0.231177  n/a   
 
 
-
 
NC_002977  MCA1441  UbiE/COQ5 family methlytransferase  38.82 
 
 
208 aa  82.8  0.000000000000003  Methylococcus capsulatus str. Bath  Bacteria  decreased coverage  0.000764793  n/a   
 
 
-
 
NC_008699  Noca_2195  phosphatidylethanolamine N-methyltransferase / phosphatidyl-N-methylethanolamine N-methyltransferase  32.93 
 
 
213 aa  82.8  0.000000000000003  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_007614  Nmul_A0349  UbiE/COQ5 methyltransferase  29.56 
 
 
199 aa  80.1  0.00000000000002  Nitrosospira multiformis ATCC 25196  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_3328  phosphatidylethanolamine N-methyltransferase / phosphatidyl-N-methylethanolamine N-methyltransferase  36.96 
 
 
210 aa  79.7  0.00000000000002  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_010424  Daud_1087  ubiquinone/menaquinone biosynthesis methyltransferase  41.35 
 
 
248 aa  73.9  0.000000000001  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.0234174  n/a   
 
 
-
 
NC_011672  PHATRDRAFT_34078  predicted protein  31.94 
 
 
260 aa  72.8  0.000000000003  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  hitchhiker  0.0000133596  n/a   
 
 
-
 
NC_010676  Bphyt_6077  Methyltransferase type 11  36.54 
 
 
277 aa  72.8  0.000000000003  Burkholderia phytofirmans PsJN  Bacteria  normal  normal  0.315329 
 
 
-
 
NC_009656  PSPA7_4720  phospholipid methyltransferase  32.08 
 
 
203 aa  72.8  0.000000000004  Pseudomonas aeruginosa PA7  Bacteria  normal  0.665331  n/a   
 
 
-
 
NC_013440  Hoch_5715  ubiquinone/menaquinone biosynthesis methyltransferase  35.44 
 
 
269 aa  72.4  0.000000000004  Haliangium ochraceum DSM 14365  Bacteria  normal  0.991449  normal 
 
 
-
 
NC_007355  Mbar_A0464  ubiquinone/menaquinone biosynthesis methyltransferase  36.84 
 
 
259 aa  71.6  0.000000000008  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal 
 
 
-
 
NC_009439  Pmen_3814  methyltransferase type 11  35.77 
 
 
203 aa  70.9  0.00000000001  Pseudomonas mendocina ymp  Bacteria  normal  normal 
 
 
-
 
NC_008463  PA14_53910  phospholipid methyltransferase  34.33 
 
 
216 aa  70.9  0.00000000001  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  0.260165  normal 
 
 
-
 
NC_013158  Huta_2905  Methyltransferase type 11  31.52 
 
 
234 aa  70.9  0.00000000001  Halorhabdus utahensis DSM 12940  Archaea  normal  n/a   
 
 
-
 
NC_010625  Bphy_5646  methyltransferase type 11  35.58 
 
 
277 aa  71.2  0.00000000001  Burkholderia phymatum STM815  Bacteria  normal  0.166193  normal  0.902058 
 
 
-
 
NC_013385  Adeg_1610  Methyltransferase type 11  38.36 
 
 
225 aa  70.5  0.00000000002  Ammonifex degensii KC4  Bacteria  normal  0.0535703  n/a   
 
 
-
 
NC_007333  Tfu_0735  phosphatidylethanolamine N-methyltransferase / phosphatidyl-N-methylethanolamine N-methyltransferase  36 
 
 
212 aa  70.5  0.00000000002  Thermobifida fusca YX  Bacteria  normal  0.837751  n/a   
 
 
-
 
NC_013235  Namu_2368  Methyltransferase type 11  30.41 
 
 
239 aa  70.1  0.00000000002  Nakamurella multipartita DSM 44233  Bacteria  decreased coverage  0.0000109502  hitchhiker  0.000328016 
 
 
-
 
NC_009635  Maeo_0509  methyltransferase type 11  32.41 
 
 
210 aa  70.5  0.00000000002  Methanococcus aeolicus Nankai-3  Archaea  normal  n/a   
 
 
-
 
NC_012029  Hlac_0551  Methyltransferase type 11  40.86 
 
 
255 aa  70.1  0.00000000002  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  0.0245261  normal 
 
 
-
 
NC_013923  Nmag_3735  Methyltransferase type 11  28.49 
 
 
245 aa  70.1  0.00000000002  Natrialba magadii ATCC 43099  Archaea  normal  0.286886  n/a   
 
 
-
 
NC_008340  Mlg_2692  methyltransferase type 11  40.38 
 
 
206 aa  70.5  0.00000000002  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  normal  0.253841 
 
 
-
 
NC_011830  Dhaf_0342  Methyltransferase type 11  36.27 
 
 
252 aa  70.5  0.00000000002  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_007355  Mbar_A3679  hypothetical protein  36.29 
 
 
244 aa  69.7  0.00000000003  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal  0.278991 
 
 
-
 
NC_007796  Mhun_0208  UbiE/COQ5 methyltransferase  34.96 
 
 
250 aa  69.7  0.00000000003  Methanospirillum hungatei JF-1  Archaea  normal  0.0448386  normal 
 
 
-
 
NC_011832  Mpal_1396  Methyltransferase type 11  36.92 
 
 
190 aa  69.7  0.00000000003  Methanosphaerula palustris E1-9c  Archaea  normal  0.482862  normal  0.887166 
 
 
-
 
NC_002967  TDE0258  UbiE/COQ5 family methlytransferase  36.45 
 
 
250 aa  68.9  0.00000000004  Treponema denticola ATCC 35405  Bacteria  normal  n/a   
 
 
-
 
NC_011726  PCC8801_0780  Methyltransferase type 11  34.78 
 
 
200 aa  69.3  0.00000000004  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_0807  Methyltransferase type 11  34.78 
 
 
200 aa  69.3  0.00000000004  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_008009  Acid345_1190  UbiE/COQ5 methyltransferase  36.72 
 
 
272 aa  69.3  0.00000000004  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_013744  Htur_4221  Methyltransferase type 11  30.38 
 
 
220 aa  68.9  0.00000000005  Haloterrigena turkmenica DSM 5511  Archaea  normal  n/a   
 
 
-
 
NC_008530  LGAS_0051  ubiquinone/menaquinone biosynthesis methyltransferase  31.03 
 
 
237 aa  68.9  0.00000000005  Lactobacillus gasseri ATCC 33323  Bacteria  normal  0.181609  normal 
 
 
-
 
NC_013440  Hoch_2840  MCP methyltransferase, CheR-type  36.5 
 
 
207 aa  68.6  0.00000000007  Haliangium ochraceum DSM 14365  Bacteria  normal  0.698056  normal  0.8759 
 
 
-
 
NC_013743  Htur_2676  Methyltransferase type 11  29.65 
 
 
231 aa  68.2  0.00000000008  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_009719  Plav_2526  methyltransferase type 11  36.45 
 
 
205 aa  68.2  0.00000000008  Parvibaculum lavamentivorans DS-1  Bacteria  normal  normal  0.0981998 
 
 
-
 
NC_007794  Saro_2319  generic methyltransferase  36.29 
 
 
210 aa  67.8  0.0000000001  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  0.897419  n/a   
 
 
-
 
NC_013743  Htur_1028  Methyltransferase type 11  35 
 
 
273 aa  67.8  0.0000000001  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_009674  Bcer98_1236  ubiquinone/menaquinone biosynthesis methyltransferase  40.57 
 
 
237 aa  67  0.0000000002  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.228899  n/a   
 
 
-
 
NC_011729  PCC7424_2834  Methyltransferase type 11  29.13 
 
 
203 aa  67  0.0000000002  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.0713675 
 
 
-
 
NC_011830  Dhaf_0334  Methyltransferase type 11  31.54 
 
 
257 aa  66.6  0.0000000002  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00000000000194414  n/a   
 
 
-
 
NC_013132  Cpin_7094  ubiquinone/menaquinone biosynthesis methyltransferase  35.92 
 
 
244 aa  67.4  0.0000000002  Chitinophaga pinensis DSM 2588  Bacteria  hitchhiker  0.0000000661752  normal 
 
 
-
 
NC_009253  Dred_2198  ubiquinone/menaquinone biosynthesis methyltransferase  38.17 
 
 
238 aa  67  0.0000000002  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_007796  Mhun_0217  UbiE/COQ5 methyltransferase  34.58 
 
 
255 aa  66.2  0.0000000003  Methanospirillum hungatei JF-1  Archaea  normal  0.0805678  normal  0.734054 
 
 
-
 
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