More than 300 homologs were found in PanDaTox collection
for query gene Rpic_1742 on replicon NC_010682
Organism: Ralstonia pickettii 12J



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010682  Rpic_1742  two component heavy metal response transcriptional regulator, winged helix family  100 
 
 
228 aa  443  1e-123  Ralstonia pickettii 12J  Bacteria  normal  normal  0.595604 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  84 
 
 
228 aa  375  1e-103  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  84.44 
 
 
228 aa  376  1e-103  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  83.56 
 
 
228 aa  377  1e-103  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  84 
 
 
228 aa  375  1e-103  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  82.02 
 
 
228 aa  370  1e-102  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_007347  Reut_A2490  heavy metal response regulator  88 
 
 
228 aa  371  1e-102  Ralstonia eutropha JMP134  Bacteria  normal  0.289616  n/a   
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  82.46 
 
 
228 aa  372  1e-102  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_007971  Rmet_6111  regulator protein CopR  88.44 
 
 
228 aa  372  1e-102  Cupriavidus metallidurans CH34  Bacteria  normal  0.110686  normal  0.158568 
 
 
-
 
NC_007974  Rmet_5672  DNA-binding response regulator  88 
 
 
228 aa  372  1e-102  Cupriavidus metallidurans CH34  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  81.33 
 
 
230 aa  360  1e-98  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  79.65 
 
 
227 aa  357  9.999999999999999e-98  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  81.28 
 
 
219 aa  349  2e-95  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_011071  Smal_2165  two component heavy metal response transcriptional regulator, winged helix family  75.56 
 
 
232 aa  333  9e-91  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.77286 
 
 
-
 
NC_007912  Sde_1948  response regulator receiver domain-containing protein  74.32 
 
 
226 aa  330  1e-89  Saccharophagus degradans 2-40  Bacteria  normal  normal  0.679676 
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  73.78 
 
 
225 aa  325  4.0000000000000003e-88  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  72.44 
 
 
225 aa  322  3e-87  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  72 
 
 
225 aa  321  6e-87  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  72 
 
 
225 aa  321  6e-87  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  72 
 
 
225 aa  321  6e-87  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  74.22 
 
 
226 aa  320  9.999999999999999e-87  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
CP001637  EcDH1_3058  two component heavy metal response transcriptional regulator, winged helix family  68.28 
 
 
227 aa  320  1.9999999999999998e-86  Escherichia coli DH1  Bacteria  normal  n/a   
 
 
-
 
NC_011353  ECH74115_0651  DNA-binding transcriptional activator CusR  68.28 
 
 
227 aa  320  1.9999999999999998e-86  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  0.589216  normal 
 
 
-
 
NC_010498  EcSMS35_0588  DNA-binding transcriptional activator CusR  68.28 
 
 
227 aa  320  1.9999999999999998e-86  Escherichia coli SMS-3-5  Bacteria  normal  0.372008  normal 
 
 
-
 
NC_007908  Rfer_0422  two component heavy metal response transcriptional regulator  72.77 
 
 
227 aa  319  1.9999999999999998e-86  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_010468  EcolC_3075  DNA-binding transcriptional activator CusR  68.28 
 
 
227 aa  320  1.9999999999999998e-86  Escherichia coli ATCC 8739  Bacteria  normal  0.204173  normal 
 
 
-
 
NC_009800  EcHS_A0618  DNA-binding transcriptional activator CusR  68.28 
 
 
227 aa  320  1.9999999999999998e-86  Escherichia coli HS  Bacteria  hitchhiker  0.000374882  n/a   
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  73.78 
 
 
226 aa  319  3e-86  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
CP001509  ECD_00532  DNA-binding response regulator in two-component regulatory system with CusS  67.84 
 
 
227 aa  318  3.9999999999999996e-86  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
NC_009801  EcE24377A_0589  DNA-binding transcriptional activator CusR  67.84 
 
 
227 aa  318  3.9999999999999996e-86  Escherichia coli E24377A  Bacteria  normal  0.180273  n/a   
 
 
-
 
NC_012892  B21_00521  hypothetical protein  67.84 
 
 
227 aa  318  3.9999999999999996e-86  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_00315  probable two component response regulator transcription regulator protein  69.74 
 
 
227 aa  317  7.999999999999999e-86  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  72.12 
 
 
228 aa  316  2e-85  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_010501  PputW619_5178  two component heavy metal response transcriptional regulator  72 
 
 
225 aa  315  3e-85  Pseudomonas putida W619  Bacteria  normal  0.341313  normal 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  72.52 
 
 
226 aa  312  1.9999999999999998e-84  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  72.52 
 
 
228 aa  311  3.9999999999999997e-84  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  71.17 
 
 
226 aa  311  6.999999999999999e-84  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_010468  EcolC_3426  DNA-binding transcriptional activator CusR  66.37 
 
 
226 aa  310  7.999999999999999e-84  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_009439  Pmen_2234  two component heavy metal response transcriptional regulator  73.33 
 
 
225 aa  308  4e-83  Pseudomonas mendocina ymp  Bacteria  normal  0.162422  normal 
 
 
-
 
NC_008573  Shewana3_4296  DNA-binding transcriptional activator CusR  65.49 
 
 
226 aa  306  1.0000000000000001e-82  Shewanella sp. ANA-3  Bacteria  decreased coverage  0.0000252174  normal 
 
 
-
 
NC_009438  Sputcn32_0258  DNA-binding transcriptional activator CusR  65.49 
 
 
226 aa  306  2.0000000000000002e-82  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_008782  Ajs_1461  two component heavy metal response transcriptional regulator  75.11 
 
 
227 aa  305  3e-82  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_009092  Shew_3258  two component heavy metal response transcriptional regulator  65.02 
 
 
238 aa  305  5.0000000000000004e-82  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00206307  normal  0.0675777 
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  70.27 
 
 
223 aa  304  7e-82  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_011901  Tgr7_1208  two component heavy metal response transcriptional regulator, winged helix family  72.12 
 
 
226 aa  304  9.000000000000001e-82  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  70.72 
 
 
226 aa  300  1e-80  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  70.72 
 
 
226 aa  299  2e-80  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  70.27 
 
 
226 aa  299  2e-80  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_010501  PputW619_1675  two component heavy metal response transcriptional regulator  71.62 
 
 
226 aa  296  2e-79  Pseudomonas putida W619  Bacteria  normal  0.294903  normal 
 
 
-
 
NC_010681  Bphyt_1510  two component heavy metal response transcriptional regulator, winged helix family  67.57 
 
 
227 aa  295  4e-79  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_007404  Tbd_1749  two component heavy metal response transcriptional regulator  72.97 
 
 
242 aa  295  5e-79  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_007347  Reut_A1815  two component heavy metal response transcriptional regulator  68.47 
 
 
224 aa  295  6e-79  Ralstonia eutropha JMP134  Bacteria  normal  0.275759  n/a   
 
 
-
 
NC_007511  Bcep18194_B2430  two component heavy metal response transcriptional regulator  66.82 
 
 
227 aa  293  1e-78  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_2725  two component heavy metal response transcriptional regulator  70.67 
 
 
227 aa  293  2e-78  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_007951  Bxe_A2960  two component heavy metal response transcriptional regulator  67.12 
 
 
227 aa  292  3e-78  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_011992  Dtpsy_2201  two component heavy metal response transcriptional regulator, winged helix family  70.67 
 
 
227 aa  292  3e-78  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_008061  Bcen_4683  two component heavy metal response transcriptional regulator  65.93 
 
 
228 aa  292  4e-78  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.222547  n/a   
 
 
-
 
NC_008543  Bcen2424_3680  two component heavy metal response transcriptional regulator  65.93 
 
 
228 aa  292  4e-78  Burkholderia cenocepacia HI2424  Bacteria  normal  0.224842  normal 
 
 
-
 
NC_010515  Bcenmc03_3842  two component heavy metal response transcriptional regulator  65.93 
 
 
227 aa  291  5e-78  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.67414 
 
 
-
 
NC_010070  Bmul_6173  two component heavy metal response transcriptional regulator  65.49 
 
 
228 aa  290  9e-78  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.400074 
 
 
-
 
NC_007973  Rmet_1751  two component heavy metal response transcriptional regulator  66.67 
 
 
224 aa  290  9e-78  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.0784096 
 
 
-
 
NC_009078  BURPS1106A_A1439  transcriptional activator IrlR  66.67 
 
 
229 aa  289  3e-77  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_006349  BMAA1028  DNA-binding response regulator IrlR  66.67 
 
 
229 aa  289  3e-77  Burkholderia mallei ATCC 23344  Bacteria  normal  0.0282692  n/a   
 
 
-
 
NC_007435  BURPS1710b_A0030  DNA-binding response regulator IrlR  66.67 
 
 
229 aa  289  3e-77  Burkholderia pseudomallei 1710b  Bacteria  normal  0.122488  n/a   
 
 
-
 
NC_009075  BURPS668_A1524  transcriptional activator protein IrlR  66.67 
 
 
229 aa  289  3e-77  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_008784  BMASAVP1_0010  transcriptional activator IrlR  66.67 
 
 
229 aa  289  3e-77  Burkholderia mallei SAVP1  Bacteria  normal  0.121051  n/a   
 
 
-
 
NC_008835  BMA10229_0402  transcriptional activator IrlR  66.67 
 
 
229 aa  289  3e-77  Burkholderia mallei NCTC 10229  Bacteria  normal  0.0800763  n/a   
 
 
-
 
NC_009079  BMA10247_A1180  transcriptional activator IrlR  66.67 
 
 
229 aa  289  3e-77  Burkholderia mallei NCTC 10247  Bacteria  normal  0.0831411  n/a   
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  63.56 
 
 
226 aa  287  1e-76  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_007650  BTH_II1376  DNA-binding response regulator IrlR  65.2 
 
 
229 aa  286  1e-76  Burkholderia thailandensis E264  Bacteria  normal  0.498923  n/a   
 
 
-
 
NC_003296  RSp0489  response regulator for cobalt zinc cadmium resistance transcription regulator protein  63.68 
 
 
224 aa  286  2e-76  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  66.22 
 
 
225 aa  286  2e-76  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  66.22 
 
 
229 aa  285  4e-76  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  62.11 
 
 
225 aa  284  7e-76  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
NC_007952  Bxe_B0708  two component heavy metal response transcriptional regulator  64.16 
 
 
226 aa  284  1.0000000000000001e-75  Burkholderia xenovorans LB400  Bacteria  normal  0.328024  normal  0.9016 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  65.32 
 
 
225 aa  283  1.0000000000000001e-75  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_007971  Rmet_5978  regulatory protein CzcR  62.11 
 
 
225 aa  282  3.0000000000000004e-75  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.0000269255  normal  0.0723212 
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  65.49 
 
 
225 aa  282  3.0000000000000004e-75  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  65.04 
 
 
225 aa  282  3.0000000000000004e-75  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_4389  two component heavy metal response transcriptional regulator, winged helix family  65.32 
 
 
226 aa  282  4.0000000000000003e-75  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  63.96 
 
 
223 aa  281  5.000000000000001e-75  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  63.72 
 
 
225 aa  281  8.000000000000001e-75  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_010512  Bcenmc03_6987  two component heavy metal response transcriptional regulator  65.92 
 
 
225 aa  280  1e-74  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.67799  normal  0.586494 
 
 
-
 
NC_008060  Bcen_1505  two component heavy metal response transcriptional regulator  65.92 
 
 
225 aa  280  1e-74  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.228186  n/a   
 
 
-
 
NC_008544  Bcen2424_6324  two component heavy metal response transcriptional regulator  65.92 
 
 
225 aa  280  1e-74  Burkholderia cenocepacia HI2424  Bacteria  normal  0.313253  normal 
 
 
-
 
NC_010468  EcolC_3412  two component heavy metal response transcriptional regulator  63.39 
 
 
226 aa  280  2e-74  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_007953  Bxe_C1381  two component heavy metal response transcriptional regulator  60.81 
 
 
224 aa  280  2e-74  Burkholderia xenovorans LB400  Bacteria  normal  normal  0.961918 
 
 
-
 
NC_007650  BTH_II0376  DNA-binding response regulator IrlR  64.86 
 
 
230 aa  279  3e-74  Burkholderia thailandensis E264  Bacteria  normal  0.083776  n/a   
 
 
-
 
NC_007435  BURPS1710b_A1103  DNA-binding response regulator IrlR  64.41 
 
 
230 aa  278  5e-74  Burkholderia pseudomallei 1710b  Bacteria  normal  0.0630149  n/a   
 
 
-
 
NC_009078  BURPS1106A_A2716  DNA-binding heavy metal response regulator  64.41 
 
 
230 aa  278  5e-74  Burkholderia pseudomallei 1106a  Bacteria  normal  0.558922  n/a   
 
 
-
 
NC_009075  BURPS668_A2869  transcriptional activator protein IrlR  64.41 
 
 
230 aa  278  5e-74  Burkholderia pseudomallei 668  Bacteria  normal  0.354021  n/a   
 
 
-
 
NC_007005  Psyr_3374  heavy metal response regulator  62.33 
 
 
229 aa  278  7e-74  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  62.61 
 
 
224 aa  276  1e-73  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_009439  Pmen_1174  two component heavy metal response transcriptional regulator  63.23 
 
 
224 aa  277  1e-73  Pseudomonas mendocina ymp  Bacteria  normal  0.216853  normal 
 
 
-
 
NC_004578  PSPTO_3603  DNA-binding heavy metal response regulator  61.88 
 
 
229 aa  275  4e-73  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.203952  n/a   
 
 
-
 
NC_007492  Pfl01_3379  two component heavy metal response transcriptional regulator  63.01 
 
 
223 aa  275  4e-73  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  62.33 
 
 
223 aa  275  5e-73  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_012880  Dd703_3722  two component heavy metal response transcriptional regulator, winged helix family  63.96 
 
 
223 aa  274  8e-73  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_3615  two component heavy metal response transcriptional regulator, winged helix family  61.71 
 
 
224 aa  274  1.0000000000000001e-72  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  60.81 
 
 
223 aa  273  1.0000000000000001e-72  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
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