More than 300 homologs were found in PanDaTox collection
for query gene Mesil_0841 on replicon NC_014212
Organism: Meiothermus silvanus DSM 9946



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_014212  Mesil_0841  two component transcriptional regulator, winged helix family  100 
 
 
223 aa  435  1e-121  Meiothermus silvanus DSM 9946  Bacteria  normal  normal 
 
 
-
 
NC_013946  Mrub_1539  two component transcriptional regulator, winged helix family  86.04 
 
 
222 aa  346  1e-94  Meiothermus ruber DSM 1279  Bacteria  hitchhiker  0.0000287281  normal  0.103291 
 
 
-
 
NC_008025  Dgeo_0130  two component transcriptional regulator  57.4 
 
 
229 aa  226  2e-58  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.848842  normal 
 
 
-
 
NC_013946  Mrub_0302  two component transcriptional regulator, winged helix family  53.39 
 
 
221 aa  215  4e-55  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_014212  Mesil_0142  two component transcriptional regulator, winged helix family  53.15 
 
 
221 aa  210  2e-53  Meiothermus silvanus DSM 9946  Bacteria  normal  normal  0.709604 
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  46.32 
 
 
232 aa  207  1e-52  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_0411  two component transcriptional regulator  48.7 
 
 
230 aa  196  2.0000000000000003e-49  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_008010  Dgeo_2564  two component transcriptional regulator  49.55 
 
 
244 aa  196  2.0000000000000003e-49  Deinococcus geothermalis DSM 11300  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  45.85 
 
 
229 aa  196  3e-49  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_010003  Pmob_0875  two component transcriptional regulator  41.3 
 
 
242 aa  192  2e-48  Petrotoga mobilis SJ95  Bacteria  decreased coverage  0.000486966  n/a   
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  47.58 
 
 
231 aa  193  2e-48  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_008025  Dgeo_0087  two component transcriptional regulator  52.25 
 
 
222 aa  192  3e-48  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal 
 
 
-
 
NC_011145  AnaeK_0439  two component transcriptional regulator, winged helix family  50.86 
 
 
230 aa  192  4e-48  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_009675  Anae109_4159  two component transcriptional regulator  46.09 
 
 
230 aa  192  5e-48  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.667277  normal  0.0359145 
 
 
-
 
NC_014212  Mesil_2802  two component transcriptional regulator, winged helix family  51.57 
 
 
219 aa  191  7e-48  Meiothermus silvanus DSM 9946  Bacteria  normal  normal  0.204502 
 
 
-
 
NC_011891  A2cp1_0440  two component transcriptional regulator, winged helix family  50.43 
 
 
230 aa  191  9e-48  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_4050  two component transcriptional regulator, winged helix family  48.23 
 
 
227 aa  190  1e-47  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00552008  n/a   
 
 
-
 
NC_011830  Dhaf_3739  two component transcriptional regulator, winged helix family  45.81 
 
 
230 aa  189  2.9999999999999997e-47  Desulfitobacterium hafniense DCB-2  Bacteria  decreased coverage  0.0000000000466515  n/a   
 
 
-
 
NC_013131  Caci_8215  two component transcriptional regulator, winged helix family  45.37 
 
 
226 aa  188  5.999999999999999e-47  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  41.63 
 
 
235 aa  187  1e-46  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  40.87 
 
 
239 aa  186  2e-46  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  40.87 
 
 
239 aa  186  2e-46  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_012560  Avin_24530  Response regulator KdpE  46.46 
 
 
232 aa  186  3e-46  Azotobacter vinelandii DJ  Bacteria  normal  0.0689152  n/a   
 
 
-
 
NC_012034  Athe_1487  two component transcriptional regulator, winged helix family  41.05 
 
 
232 aa  186  3e-46  Anaerocellum thermophilum DSM 6725  Bacteria  normal  0.487145  n/a   
 
 
-
 
NC_008578  Acel_0088  two component transcriptional regulator  45.41 
 
 
228 aa  186  3e-46  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_013947  Snas_4021  two component transcriptional regulator, winged helix family  47.16 
 
 
235 aa  185  4e-46  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  43.61 
 
 
226 aa  185  4e-46  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  44.98 
 
 
235 aa  185  5e-46  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009767  Rcas_2782  two component transcriptional regulator  46.22 
 
 
231 aa  184  7e-46  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.92379  normal 
 
 
-
 
NC_011831  Cagg_3302  two component transcriptional regulator, winged helix family  45.85 
 
 
231 aa  184  8e-46  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.000343135 
 
 
-
 
NC_014210  Ndas_4322  two component transcriptional regulator, winged helix family  44.93 
 
 
231 aa  183  1.0000000000000001e-45  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_010424  Daud_1419  two component transcriptional regulator  47.39 
 
 
231 aa  183  1.0000000000000001e-45  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.0720218  n/a   
 
 
-
 
NC_011899  Hore_21640  two component transcriptional regulator, winged helix family  42.29 
 
 
226 aa  184  1.0000000000000001e-45  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000000176926  n/a   
 
 
-
 
NC_013595  Sros_0961  response regulator receiver protein  44.93 
 
 
229 aa  183  2.0000000000000003e-45  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_007484  Noc_2401  phosphate regulon transcriptional regulatory protein phoB  47.79 
 
 
229 aa  182  2.0000000000000003e-45  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_009524  PsycPRwf_2093  two component transcriptional regulator  45.74 
 
 
233 aa  183  2.0000000000000003e-45  Psychrobacter sp. PRwf-1  Bacteria  normal  0.582679  normal 
 
 
-
 
NC_013510  Tcur_0700  two component transcriptional regulator, winged helix family  44.05 
 
 
226 aa  183  2.0000000000000003e-45  Thermomonospora curvata DSM 43183  Bacteria  normal  0.768939  n/a   
 
 
-
 
NC_008709  Ping_2232  two component transcriptional regulator, winged helix family protein  44.25 
 
 
227 aa  183  2.0000000000000003e-45  Psychromonas ingrahamii 37  Bacteria  normal  0.326614  normal  0.43086 
 
 
-
 
NC_008148  Rxyl_0378  two component transcriptional regulator  44.64 
 
 
234 aa  182  3e-45  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_2333  two component transcriptional regulator  42.06 
 
 
232 aa  182  3e-45  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_013174  Jden_2083  two component transcriptional regulator, winged helix family  42.44 
 
 
237 aa  182  3e-45  Jonesia denitrificans DSM 20603  Bacteria  normal  0.873655  normal 
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  46.09 
 
 
232 aa  182  4.0000000000000006e-45  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_013440  Hoch_0552  two component transcriptional regulator, winged helix family  46.64 
 
 
226 aa  182  5.0000000000000004e-45  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.496663 
 
 
-
 
NC_013422  Hneap_2266  two component transcriptional regulator PhoB, winged helix family  45.05 
 
 
230 aa  181  7e-45  Halothiobacillus neapolitanus c2  Bacteria  normal  n/a   
 
 
-
 
NC_009457  VC0395_A0253  DNA-binding response regulator PhoB  44.69 
 
 
229 aa  181  7e-45  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_008578  Acel_1832  two component transcriptional regulator  46.09 
 
 
245 aa  181  7e-45  Acidothermus cellulolyticus 11B  Bacteria  normal  0.366424  normal  0.561636 
 
 
-
 
NC_002977  MCA3105  DNA-binding response regulator PhoB  44.2 
 
 
232 aa  181  8.000000000000001e-45  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_009455  DehaBAV1_0235  two component transcriptional regulator  44.64 
 
 
230 aa  181  8.000000000000001e-45  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_013205  Aaci_2570  two component transcriptional regulator, winged helix family  42.37 
 
 
239 aa  181  8.000000000000001e-45  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_1917  two component transcriptional regulator  42.73 
 
 
238 aa  181  9.000000000000001e-45  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.332821 
 
 
-
 
NC_013552  DhcVS_143  DNA-binding response regulator, two-component system, OmpR family  44.1 
 
 
256 aa  181  1e-44  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_4602  two component transcriptional regulator, winged helix family  43.17 
 
 
226 aa  180  1e-44  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_1997  two component transcriptional regulator  42.17 
 
 
234 aa  181  1e-44  Thermoanaerobacter sp. X514  Bacteria  hitchhiker  0.000000742772  n/a   
 
 
-
 
NC_003910  CPS_1208  phosphate regulon response regulator PhoB  42.17 
 
 
233 aa  179  2e-44  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_009436  Ent638_0867  transcriptional regulator PhoB  45.58 
 
 
229 aa  179  2e-44  Enterobacter sp. 638  Bacteria  normal  0.437737  normal 
 
 
-
 
NC_007643  Rru_A0603  two component transcriptional regulator  44.64 
 
 
233 aa  179  2e-44  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.0519325  n/a   
 
 
-
 
NC_010159  YpAngola_A3286  phosphate regulon transcriptional regulatory protein  45.13 
 
 
230 aa  179  2e-44  Yersinia pestis Angola  Bacteria  normal  normal  0.0413143 
 
 
-
 
NC_011149  SeAg_B0435  transcriptional regulator PhoB  46.02 
 
 
229 aa  180  2e-44  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  n/a   
 
 
-
 
NC_008825  Mpe_A1277  two component transcriptional regulator  47.14 
 
 
233 aa  180  2e-44  Methylibium petroleiphilum PM1  Bacteria  normal  0.0649233  normal  0.253886 
 
 
-
 
NC_009708  YpsIP31758_3136  phosphate regulon transcriptional regulatory protein PhoB  45.13 
 
 
229 aa  179  2.9999999999999997e-44  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_010465  YPK_3276  two component transcriptional regulator  45.13 
 
 
229 aa  179  2.9999999999999997e-44  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_013165  Shel_00330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  43.61 
 
 
240 aa  179  2.9999999999999997e-44  Slackia heliotrinireducens DSM 20476  Bacteria  decreased coverage  0.00972196  normal 
 
 
-
 
NC_013170  Ccur_11690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  44.05 
 
 
236 aa  179  2.9999999999999997e-44  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.52451  normal 
 
 
-
 
NC_013501  Rmar_0987  two component transcriptional regulator, winged helix family  46.96 
 
 
233 aa  179  2.9999999999999997e-44  Rhodothermus marinus DSM 4252  Bacteria  normal  0.195539  n/a   
 
 
-
 
NC_013093  Amir_6749  two component transcriptional regulator, winged helix family  44.05 
 
 
226 aa  179  2.9999999999999997e-44  Actinosynnema mirum DSM 43827  Bacteria  normal  0.290774  n/a   
 
 
-
 
NC_013205  Aaci_2922  two component transcriptional regulator, winged helix family  44.21 
 
 
230 aa  179  4e-44  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.221617  n/a   
 
 
-
 
NC_010001  Cphy_1954  two component transcriptional regulator  40.09 
 
 
229 aa  179  4e-44  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.000155813  n/a   
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  44.3 
 
 
236 aa  179  4e-44  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  43.17 
 
 
229 aa  179  4e-44  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_007644  Moth_0827  two component transcriptional regulator  46.67 
 
 
256 aa  178  4.999999999999999e-44  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00211389  normal  0.244563 
 
 
-
 
NC_009832  Spro_1041  two component transcriptional regulator  45.13 
 
 
229 aa  178  4.999999999999999e-44  Serratia proteamaculans 568  Bacteria  normal  normal  0.194422 
 
 
-
 
NC_013204  Elen_0258  two component transcriptional regulator, winged helix family  43.61 
 
 
236 aa  178  5.999999999999999e-44  Eggerthella lenta DSM 2243  Bacteria  normal  0.606292  normal 
 
 
-
 
NC_002936  DET0135  DNA-binding response regulator  44.98 
 
 
230 aa  177  8e-44  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_007406  Nwi_0511  phosphate regulon transcriptional regulatory protein phoB  46.05 
 
 
234 aa  177  8e-44  Nitrobacter winogradskyi Nb-255  Bacteria  normal  normal  0.473137 
 
 
-
 
NC_008228  Patl_1053  two component transcriptional regulator  43.29 
 
 
229 aa  178  8e-44  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_011083  SeHA_C0496  transcriptional regulator PhoB  45.58 
 
 
229 aa  177  9e-44  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  normal 
 
 
-
 
NC_007404  Tbd_0216  two component transcriptional regulator  45.58 
 
 
230 aa  177  9e-44  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal  0.305183 
 
 
-
 
NC_011094  SeSA_A0454  transcriptional regulator PhoB  45.58 
 
 
229 aa  177  9e-44  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  normal 
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  46.61 
 
 
236 aa  177  9e-44  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_011205  SeD_A0435  transcriptional regulator PhoB  45.58 
 
 
229 aa  177  9e-44  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  0.464381  normal 
 
 
-
 
NC_011883  Ddes_0567  two component transcriptional regulator, winged helix family  48.7 
 
 
225 aa  177  9e-44  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  0.463355  n/a   
 
 
-
 
CP001637  EcDH1_3210  two component transcriptional regulator PhoB, winged helix family  45.58 
 
 
229 aa  177  1e-43  Escherichia coli DH1  Bacteria  normal  0.146413  n/a   
 
 
-
 
NC_010320  Teth514_1155  two component transcriptional regulator  39.3 
 
 
231 aa  177  1e-43  Thermoanaerobacter sp. X514  Bacteria  decreased coverage  0.000000430064  n/a   
 
 
-
 
NC_009800  EcHS_A0467  transcriptional regulator PhoB  45.58 
 
 
229 aa  177  1e-43  Escherichia coli HS  Bacteria  normal  n/a   
 
 
-
 
NC_009801  EcE24377A_0427  transcriptional regulator PhoB  45.58 
 
 
229 aa  177  1e-43  Escherichia coli E24377A  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_0580  two component transcriptional regulator, winged helix family  42.29 
 
 
226 aa  177  1e-43  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_013203  Apar_1349  two component transcriptional regulator, winged helix family  44 
 
 
237 aa  177  1e-43  Atopobium parvulum DSM 20469  Bacteria  normal  normal  0.421984 
 
 
-
 
NC_010658  SbBS512_E0318  transcriptional regulator PhoB  45.58 
 
 
229 aa  177  1e-43  Shigella boydii CDC 3083-94  Bacteria  normal  n/a   
 
 
-
 
NC_011353  ECH74115_0475  transcriptional regulator PhoB  45.58 
 
 
229 aa  177  1e-43  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  normal 
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  42.36 
 
 
234 aa  177  1e-43  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_010498  EcSMS35_0429  transcriptional regulator PhoB  45.58 
 
 
229 aa  177  1e-43  Escherichia coli SMS-3-5  Bacteria  normal  0.283039  normal 
 
 
-
 
NC_009616  Tmel_1838  two component transcriptional regulator  38.7 
 
 
239 aa  177  1e-43  Thermosipho melanesiensis BI429  Bacteria  hitchhiker  0.00000194698  n/a   
 
 
-
 
NC_010468  EcolC_3234  transcriptional regulator PhoB  45.58 
 
 
229 aa  177  1e-43  Escherichia coli ATCC 8739  Bacteria  normal  0.456974  unclonable  0.00000000819474 
 
 
-
 
NC_007947  Mfla_0489  two component transcriptional regulator  45.58 
 
 
228 aa  177  1e-43  Methylobacillus flagellatus KT  Bacteria  normal  normal 
 
 
-
 
NC_007964  Nham_0640  two component transcriptional regulator  46.05 
 
 
233 aa  177  1e-43  Nitrobacter hamburgensis X14  Bacteria  normal  0.772339  n/a   
 
 
-
 
NC_012034  Athe_0080  two component transcriptional regulator, winged helix family  41.33 
 
 
230 aa  177  1e-43  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_010816  BLD_1073  putative response regulator  40.52 
 
 
234 aa  177  1e-43  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_012917  PC1_1008  two component transcriptional regulator PhoB, winged helix family  44.69 
 
 
229 aa  177  1e-43  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  n/a   
 
 
-
 
NC_008541  Arth_0724  two component transcriptional regulator  41.41 
 
 
226 aa  177  1e-43  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_013421  Pecwa_3302  two component transcriptional regulator PhoB, winged helix family  44.69 
 
 
229 aa  177  1e-43  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
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