71 homologs were found in PanDaTox collection
for query gene Maeo_0718 on replicon NC_009635
Organism: Methanococcus aeolicus Nankai-3



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  100 
 
 		 418 aa  852    Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
-
 
NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  73.96 
 
 		 408 aa  616  1e-175  Methanococcus maripaludis C7  Archaea  normal  1  normal  1 
 
 
-
 
NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  73.22 
 
 		 408 aa  611  9.999999999999999e-175  Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
-
 
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  72.97 
 
 		 408 aa  611  9.999999999999999e-175  Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  72.2 
 
 		 411 aa  605  9.999999999999999e-173  Methanococcus vannielii SB  Archaea  normal  1  n/a   
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  49.51 
 
 		 403 aa  406  1.0000000000000001e-112  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_011832  Mpal_2647  3-hydroxy-3-methylglutaryl Coenzyme A reductase  51.72 
 
 		 407 aa  403  1e-111  Methanosphaerula palustris E1-9c  Archaea  normal  0.259986  normal  0.338347 
 
 
-
 
NC_007796  Mhun_3004  3-hydroxy-3-methylglutaryl coenzyme A reductase  52.7 
 
 		 401 aa  399  9.999999999999999e-111  Methanospirillum hungatei JF-1  Archaea  normal  1  normal  1 
 
 
-
 
NC_009712  Mboo_0137  3-hydroxy-3-methylglutaryl coenzyme A reductase  51.35 
 
 		 426 aa  397  1e-109  Candidatus Methanoregula boonei 6A8  Archaea  normal  1  normal  1 
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  51.47 
 
 		 402 aa  389  1e-107  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
NC_008942  Mlab_1655  3-hydroxy-3-methylglutaryl-coenzyme A reductase  50.74 
 
 		 404 aa  389  1e-107  Methanocorpusculum labreanum Z  Archaea  normal  1  hitchhiker  0.0000342006 
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  48.49 
 
 		 395 aa  385  1e-106  Thermoproteus neutrophilus V24Sta  Archaea  normal  1  normal  1 
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  48.66 
 
 		 403 aa  386  1e-106  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal  1 
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  49.39 
 
 		 409 aa  382  1e-105  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  51.01 
 
 		 398 aa  376  1e-103  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  52.21 
 
 		 418 aa  376  1e-103  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  53.3 
 
 		 414 aa  374  1e-102  Methanococcoides burtonii DSM 6242  Archaea  normal  1  n/a   
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  48.41 
 
 		 410 aa  363  4e-99  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal  1 
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  50.25 
 
 		 399 aa  363  4e-99  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  46.38 
 
 		 410 aa  362  6e-99  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  50.5 
 
 		 399 aa  361  1e-98  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  47.34 
 
 		 408 aa  360  2e-98  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  47.82 
 
 		 410 aa  356  3.9999999999999996e-97  Caldivirga maquilingensis IC-167  Archaea  normal  1  normal  1 
 
 
-
 
NC_012029  Hlac_2019  3-hydroxy-3-methylglutaryl Coenzyme A reductase  46.08 
 
 		 407 aa  321  9.999999999999999e-87  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  0.439309 
 
 
-
 
NC_008228  Patl_0427  hydroxymethylglutaryl-CoA reductase (NADPH)  42.67 
 
 		 395 aa  304  2.0000000000000002e-81  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.601953  n/a   
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  42.69 
 
 		 1283 aa  301  1e-80  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  1  n/a   
 
 
-
 
NC_009456  VC0395_0662  hydroxymethylglutaryl-coenzyme A reductase  45.8 
 
 		 420 aa  292  6e-78  Vibrio cholerae O395  Bacteria  normal  1  n/a   
 
 
-
 
NC_011138  MADE_03398  Hydroxymethylglutaryl-coenzyme A reductase  40.68 
 
 		 396 aa  286  4e-76  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_013457  VEA_000087  hydroxymethylglutaryl-CoA reductase  43.08 
 
 		 420 aa  284  2.0000000000000002e-75  Vibrio sp. Ex25  Bacteria  normal  1  n/a   
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  39.26 
 
 		 1047 aa  276  6e-73  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_009784  VIBHAR_05704  3-hydroxy-3-methylglutaryl CoA reductase  43.04 
 
 		 420 aa  275  1.0000000000000001e-72  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_011313  VSAL_II0253  putative 3-hydroxy-3-methylglutaryl coenzyme a reductase  43.54 
 
 		 419 aa  268  1e-70  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.0262386  n/a   
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  43.06 
 
 		 1125 aa  265  8.999999999999999e-70  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
BN001307  ANIA_01593  conserved hypothetical protein  41.3 
 
 		 416 aa  263  4.999999999999999e-69  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_011697  PHATRDRAFT_16870  predicted protein  43.99 
 
 		 367 aa  256  6e-67  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  1  n/a   
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  41.32 
 
 		 514 aa  253  4.0000000000000004e-66  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  41.67 
 
 		 424 aa  235  1.0000000000000001e-60  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_010117  COXBURSA331_A2174  hydroxymethylglutaryl-coenzyme A reductase  33.92 
 
 		 395 aa  216  7e-55  Coxiella burnetii RSA 331  Bacteria  normal  0.0352988  n/a   
 
 
-
 
NC_009727  CBUD_0622  3-hydroxy-3-methylglutaryl-coenzyme A reductase  39.83 
 
 		 357 aa  216  8e-55  Coxiella burnetii Dugway 5J108-111  Bacteria  hitchhiker  0.000221084  n/a   
 
 
-
 
NC_010117  COXBURSA331_A0723  hydroxymethylglutaryl-CoA reductase (NADPH)  39.83 
 
 		 355 aa  216  8e-55  Coxiella burnetii RSA 331  Bacteria  hitchhiker  0.000000000015079  n/a   
 
 
-
 
NC_007520  Tcr_1717  hydroxymethylglutaryl-CoA reductase (NADPH)  37.9 
 
 		 352 aa  209  9e-53  Thiomicrospira crunogena XCL-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_009727  CBUD_0151  3-hydroxy-3-methylglutaryl-coenzyme A reductase  31.39 
 
 		 364 aa  184  2.0000000000000003e-45  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  1  n/a   
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  24.4 
 
 		 429 aa  69.3  0.0000000001  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_008528  OEOE_1799  3-hydroxy-3-methylglutaryl-coenzyme A reductase  25.41 
 
 		 363 aa  67  0.0000000006  Oenococcus oeni PSU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  24.25 
 
 		 419 aa  66.2  0.000000001  Methanosaeta thermophila PT  Archaea  normal  1  n/a   
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  26.88 
 
 		 406 aa  60.5  0.00000006  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  24.07 
 
 		 425 aa  58.9  0.0000002  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  24.1 
 
 		 410 aa  57.4  0.0000005  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
-
 
NC_004116  SAG1317  3-hydroxy-3-methylglutaryl-CoA reductase  26.25 
 
 		 427 aa  56.6  0.0000007  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_011728  BbuZS7_0705  hydroxymethylglutaryl-CoA reductase, degradative  24.1 
 
 		 422 aa  55.8  0.000001  Borrelia burgdorferi ZS7  Bacteria  normal  1  n/a   
 
 
-
 
NC_010085  Nmar_1560  hydroxymethylglutaryl-CoA reductase, degradative  24.75 
 
 		 418 aa  56.2  0.000001  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  1 
 
 
-
 
NC_009513  Lreu_0206  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.76 
 
 		 420 aa  54.3  0.000004  Lactobacillus reuteri DSM 20016  Bacteria  normal  1  n/a   
 
 
-
 
NC_008698  Tpen_0927  hydroxymethylglutaryl-CoA reductase, degradative  24.7 
 
 		 428 aa  54.3  0.000004  Thermofilum pendens Hrk 5  Archaea  normal  1  n/a   
 
 
-
 
NC_011831  Cagg_1141  hydroxymethylglutaryl-CoA reductase, degradative  24.67 
 
 		 440 aa  53.1  0.000008  Chloroflexus aggregans DSM 9485  Bacteria  normal  1  hitchhiker  0.00353445 
 
 
-
 
NC_009512  Pput_3073  hydroxymethylglutaryl-CoA reductase, degradative  23.81 
 
 		 428 aa  51.2  0.00003  Pseudomonas putida F1  Bacteria  normal  0.272086  normal  1 
 
 
-
 
NC_006369  lpl2030  hypothetical protein  21.99 
 
 		 432 aa  51.6  0.00003  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_006368  lpp2035  hypothetical protein  21.73 
 
 		 432 aa  51.6  0.00003  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  23.18 
 
 		 444 aa  50.8  0.00004  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  23.42 
 
 		 429 aa  50.4  0.00006  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  22.46 
 
 		 425 aa  50.1  0.00007  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  22.46 
 
 		 425 aa  50.1  0.00007  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_009972  Haur_3539  hydroxymethylglutaryl-CoA reductase, degradative  24.19 
 
 		 441 aa  49.3  0.0001  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0777406  n/a   
 
 
-
 
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  23.44 
 
 		 456 aa  48.9  0.0002  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  0.316381 
 
 
-
 
NC_008531  LEUM_0335  hydroxymethylglutaryl-CoA reductase  25.4 
 
 		 401 aa  47  0.0007  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  1  n/a   
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  24.01 
 
 		 437 aa  46.2  0.001  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_014230  CA2559_04185  3-hydroxy-3-methylglutaryl-coenzyme A reductase  21.58 
 
 		 436 aa  45.4  0.002  Croceibacter atlanticus HTCC2559  Bacteria  normal  1  n/a   
 
 
-
 
NC_008532  STER_0620  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.64 
 
 		 423 aa  44.3  0.004  Streptococcus thermophilus LMD-9  Bacteria  normal  1  n/a   
 
 
-
 
NC_007650  BTH_II1513  hypothetical protein  23.96 
 
 		 270 aa  44.3  0.004  Burkholderia thailandensis E264  Bacteria  normal  0.175272  n/a   
 
 
-
 
NC_009078  BURPS1106A_A1219  hypothetical protein  24.49 
 
 		 282 aa  43.9  0.005  Burkholderia pseudomallei 1106a  Bacteria  normal  0.264003  n/a   
 
 
-
 
NC_009075  BURPS668_A1291  hypothetical protein  24.49 
 
 		 282 aa  43.9  0.005  Burkholderia pseudomallei 668  Bacteria  normal  0.132365  n/a   
 
 
-
 
NC_007435  BURPS1710b_A2482  hypothetical protein  24.49 
 
 		 273 aa  43.9  0.005  Burkholderia pseudomallei 1710b  Bacteria  normal  1  n/a   
 
 
-
 
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