103 homologs were found in PanDaTox collection
for query gene MCA1666 on replicon NC_002977
Organism: Methylococcus capsulatus str. Bath



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_002977  MCA1666  sensor histidine kinase  100 
 
 
142 aa  291  3e-78  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_008554  Sfum_4032  putative anti-sigma regulatory factor, serine/threonine protein kinase  41.22 
 
 
155 aa  104  3e-22  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_009511  Swit_1493  putative anti-sigma regulatory factor, serine/threonine protein kinase  37.04 
 
 
132 aa  95.9  2e-19  Sphingomonas wittichii RW1  Bacteria  normal  normal 
 
 
-
 
NC_008346  Swol_1794  putative anti-sigma regulatory factor, serine/threonine protein kinase  40.68 
 
 
134 aa  92.8  1e-18  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_2419  cyclic nucleotide-binding protein  36.64 
 
 
563 aa  88.2  3e-17  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.871595  normal 
 
 
-
 
NC_009712  Mboo_1160  putative anti-sigma regulatory factor, serine/threonine protein kinase  35.38 
 
 
138 aa  87.8  4e-17  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.620968  normal 
 
 
-
 
NC_011831  Cagg_2555  anti-sigma-factor antagonist  37.84 
 
 
249 aa  87.4  6e-17  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_013889  TK90_1874  putative anti-sigma regulatory factor, serine/threonine protein kinase  36.72 
 
 
137 aa  85.1  3e-16  Thioalkalivibrio sp. K90mix  Bacteria  normal  0.122382  normal 
 
 
-
 
NC_009767  Rcas_1195  anti-sigma-factor antagonist  35.94 
 
 
269 aa  82.4  0.000000000000002  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.123525  normal 
 
 
-
 
NC_009051  Memar_2469  putative anti-sigma regulatory factor, serine/threonine protein kinase  38.68 
 
 
135 aa  80.5  0.000000000000007  Methanoculleus marisnigri JR1  Archaea  normal  n/a   
 
 
-
 
NC_009523  RoseRS_2161  anti-sigma-factor antagonist  36.07 
 
 
250 aa  80.5  0.000000000000007  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_008942  Mlab_1452  hypothetical protein  33.86 
 
 
777 aa  75.5  0.0000000000002  Methanocorpusculum labreanum Z  Archaea  normal  normal 
 
 
-
 
NC_009972  Haur_4167  cyclic nucleotide-binding protein  39.8 
 
 
570 aa  75.1  0.0000000000003  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_013501  Rmar_2331  putative anti-sigma regulatory factor, serine/threonine protein kinase  31.43 
 
 
151 aa  75.1  0.0000000000003  Rhodothermus marinus DSM 4252  Bacteria  normal  0.571842  n/a   
 
 
-
 
NC_013216  Dtox_0933  putative anti-sigma regulatory factor, serine/threonine protein kinase  28.99 
 
 
142 aa  73.6  0.0000000000008  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.0815302  normal  0.189071 
 
 
-
 
NC_011884  Cyan7425_0700  putative anti-sigma regulatory factor, serine/threonine protein kinase  34.43 
 
 
136 aa  73.6  0.0000000000009  Cyanothece sp. PCC 7425  Bacteria  normal  normal 
 
 
-
 
NC_011832  Mpal_1929  putative anti-sigma regulatory factor, serine/threonine protein kinase  37.14 
 
 
139 aa  73.2  0.000000000001  Methanosphaerula palustris E1-9c  Archaea  normal  0.0887571  normal  0.148865 
 
 
-
 
NC_009972  Haur_1422  anti-sigma-factor antagonist  34.13 
 
 
250 aa  71.6  0.000000000003  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_007796  Mhun_0063  putative anti-sigma regulatory factor (serine/threonine protein kinase)  29.41 
 
 
140 aa  70.5  0.000000000007  Methanospirillum hungatei JF-1  Archaea  normal  normal  0.0713993 
 
 
-
 
NC_013440  Hoch_4441  protein serine phosphatase with GAF(s) sensor(s)  37.07 
 
 
792 aa  70.5  0.000000000008  Haliangium ochraceum DSM 14365  Bacteria  normal  0.794262  normal 
 
 
-
 
NC_013204  Elen_2936  putative anti-sigma regulatory factor, serine/threonine protein kinase  35.85 
 
 
140 aa  69.7  0.00000000001  Eggerthella lenta DSM 2243  Bacteria  normal  normal 
 
 
-
 
NC_007519  Dde_0721  serine phosphatase  30.77 
 
 
885 aa  68.9  0.00000000002  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_011060  Ppha_1014  putative anti-sigma regulatory factor, serine/threonine protein kinase  31.91 
 
 
147 aa  69.3  0.00000000002  Pelodictyon phaeoclathratiforme BU-1  Bacteria  hitchhiker  0.000121242  n/a   
 
 
-
 
NC_008639  Cpha266_1826  putative anti-sigma regulatory factor, serine/threonine protein kinase  31.36 
 
 
147 aa  67.8  0.00000000005  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  n/a   
 
 
-
 
NC_013530  Xcel_2857  putative anti-sigma regulatory factor, serine/threonine protein kinase  32.06 
 
 
136 aa  67  0.00000000008  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_2650  putative anti-sigma regulatory factor, serine/threonine protein kinase  32.23 
 
 
141 aa  65.9  0.0000000002  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_1584  putative anti-sigma regulatory factor, serine/threonine protein kinase  32.23 
 
 
141 aa  65.9  0.0000000002  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_007298  Daro_1990  sensor histidine kinase  32.03 
 
 
132 aa  63.9  0.0000000007  Dechloromonas aromatica RCB  Bacteria  normal  0.415496  normal  0.485112 
 
 
-
 
NC_010717  PXO_03913  hypothetical protein  30.43 
 
 
143 aa  63.9  0.0000000007  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_2664  putative anti-sigma regulatory factor, serine/threonine protein kinase  33.33 
 
 
139 aa  62.4  0.000000002  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_1525  putative anti-sigma regulatory factor, serine/threonine protein kinase  36 
 
 
141 aa  62.8  0.000000002  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_009720  Xaut_2527  putative anti-sigma regulatory factor, serine/threonine protein kinase  29.92 
 
 
147 aa  62.4  0.000000002  Xanthobacter autotrophicus Py2  Bacteria  normal  0.557848  normal 
 
 
-
 
NC_007512  Plut_0863  putative anti-sigma regulatory factor  28 
 
 
143 aa  59.3  0.00000002  Chlorobium luteolum DSM 273  Bacteria  normal  normal  0.286315 
 
 
-
 
NC_007512  Plut_1040  putative anti-sigma regulatory factor (serine/threonine protein kinase)  28 
 
 
143 aa  58.9  0.00000002  Chlorobium luteolum DSM 273  Bacteria  normal  0.469899  normal  0.536702 
 
 
-
 
NC_008312  Tery_5013  putative anti-sigma regulatory factor, serine/threonine protein kinase  29.6 
 
 
141 aa  59.3  0.00000002  Trichodesmium erythraeum IMS101  Bacteria  normal  normal 
 
 
-
 
NC_008609  Ppro_2661  putative anti-sigma regulatory factor, serine/threonine protein kinase  32 
 
 
151 aa  58.2  0.00000004  Pelobacter propionicus DSM 2379  Bacteria  normal  0.0789133  n/a   
 
 
-
 
NC_008741  Dvul_2982  putative anti-sigma regulatory factor, serine/threonine protein kinase  32.79 
 
 
138 aa  56.6  0.0000001  Desulfovibrio vulgaris DP4  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_2441  putative anti-sigma regulatory factor, serine/threonine protein kinase  37.76 
 
 
138 aa  56.6  0.0000001  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_002620  TC0837  RsbW protein, putative  33.96 
 
 
152 aa  55.5  0.0000003  Chlamydia muridarum Nigg  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU1426  rsbW protein, putative  28.35 
 
 
149 aa  55.1  0.0000003  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_1228  putative anti-sigma regulatory factor (serine/threonine protein kinase)  27.97 
 
 
144 aa  54.7  0.0000004  Geobacter metallireducens GS-15  Bacteria  normal  normal  0.011235 
 
 
-
 
NC_009483  Gura_2043  putative anti-sigma regulatory factor, serine/threonine protein kinase  31.13 
 
 
141 aa  54.3  0.0000005  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000388253  n/a   
 
 
-
 
NC_007413  Ava_3443  putative anti-sigma regulatory factor (Ser/Thr protein kinase)  29.41 
 
 
147 aa  53.1  0.000001  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0106512  normal 
 
 
-
 
NC_009712  Mboo_1022  putative anti-sigma regulatory factor, serine/threonine protein kinase  25.77 
 
 
116 aa  53.1  0.000001  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.126342  normal 
 
 
-
 
NC_010814  Glov_0750  putative anti-sigma regulatory factor, serine/threonine protein kinase  27.5 
 
 
141 aa  52.8  0.000001  Geobacter lovleyi SZ  Bacteria  normal  0.194451  n/a   
 
 
-
 
NC_011831  Cagg_2065  putative anti-sigma regulatory factor, serine/threonine protein kinase  29.36 
 
 
143 aa  52.4  0.000002  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_002977  MCA1685  anti-sigma B factor  32.67 
 
 
142 aa  50.1  0.00001  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_1875  anti-sigma regulatory factor  30.56 
 
 
139 aa  49.7  0.00001  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.000000201046  n/a   
 
 
-
 
NC_008255  CHU_0193  hypothetical protein  25.69 
 
 
140 aa  50.1  0.00001  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  normal 
 
 
-
 
NC_009511  Swit_1232  putative anti-sigma regulatory factor, serine/threonine protein kinase  33.05 
 
 
139 aa  49.7  0.00001  Sphingomonas wittichii RW1  Bacteria  normal  0.240625  normal  0.172209 
 
 
-
 
NC_010803  Clim_1839  putative anti-sigma regulatory factor, serine/threonine protein kinase  31.25 
 
 
140 aa  50.1  0.00001  Chlorobium limicola DSM 245  Bacteria  normal  0.481374  n/a   
 
 
-
 
NC_007484  Noc_2977  anti-sigma regulatory factor (Ser/Thr protein kinase  31.37 
 
 
141 aa  48.5  0.00003  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_2468  putative anti-sigma regulatory factor, serine/threonine protein kinase  23.45 
 
 
147 aa  48.1  0.00004  Geobacter bemidjiensis Bem  Bacteria  normal  0.0214018  n/a   
 
 
-
 
NC_013173  Dbac_0348  putative anti-sigma regulatory factor, serine/threonine protein kinase  30.1 
 
 
147 aa  48.1  0.00004  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_014248  Aazo_1701  putative anti-sigma regulatory factor serine/threonine protein kinase  24.63 
 
 
140 aa  46.2  0.0001  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_6901  signal transduction histidine kinase  50 
 
 
465 aa  46.2  0.0001  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_011368  Rleg2_4826  signal transduction histidine kinase  28.46 
 
 
553 aa  46.6  0.0001  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.788722  normal  0.27838 
 
 
-
 
NC_013757  Gobs_3675  putative anti-sigma regulatory factor, serine/threonine protein kinase  28.57 
 
 
143 aa  46.2  0.0001  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.709341  n/a   
 
 
-
 
NC_012918  GM21_1749  putative anti-sigma regulatory factor, serine/threonine protein kinase  22.76 
 
 
147 aa  45.8  0.0002  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_002976  SERP1678  serine-protein kinase RsbW  26.32 
 
 
159 aa  45.4  0.0003  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_2188  putative anti-sigma regulatory factor, serine/threonine protein kinase  25.62 
 
 
142 aa  45.1  0.0003  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_3192  multi-sensor signal transduction histidine kinase  33.33 
 
 
864 aa  45.1  0.0003  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.0309229 
 
 
-
 
NC_010725  Mpop_4106  signal transduction histidine kinase  40 
 
 
453 aa  45.4  0.0003  Methylobacterium populi BJ001  Bacteria  normal  0.0707076  normal 
 
 
-
 
NC_010814  Glov_2102  putative anti-sigma regulatory factor, serine/threonine protein kinase  27.05 
 
 
143 aa  44.7  0.0005  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_3034  putative anti-sigma regulatory factor, serine/threonine protein kinase  32.94 
 
 
155 aa  44.7  0.0005  Chloroflexus aggregans DSM 9485  Bacteria  normal  decreased coverage  0.00000275353 
 
 
-
 
NC_008312  Tery_0922  putative anti-sigma regulatory factor, serine/threonine protein kinase  26.92 
 
 
148 aa  44.3  0.0006  Trichodesmium erythraeum IMS101  Bacteria  normal  normal 
 
 
-
 
NC_008751  Dvul_2096  signal transduction histidine kinase  33.82 
 
 
526 aa  44.3  0.0006  Desulfovibrio vulgaris DP4  Bacteria  normal  normal  0.0713574 
 
 
-
 
NC_010505  Mrad2831_3723  multi-sensor signal transduction histidine kinase  35.16 
 
 
871 aa  43.9  0.0008  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.086011 
 
 
-
 
NC_008346  Swol_1997  putative anti-sigma regulatory factor, serine/threonine protein kinase  25.93 
 
 
495 aa  43.5  0.001  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_1624  putative anti-sigma regulatory factor, serine/threonine protein kinase  28.57 
 
 
154 aa  43.1  0.001  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_010483  TRQ2_0194  putative anti-sigma regulatory factor, serine/threonine protein kinase  28.45 
 
 
136 aa  43.5  0.001  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_011894  Mnod_6649  signal transduction histidine kinase  37.5 
 
 
739 aa  43.1  0.001  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_008009  Acid345_2515  putative anti-sigma regulatory factor, serine/threonine protein kinase  21.43 
 
 
148 aa  42.4  0.002  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.538602  normal  0.204677 
 
 
-
 
NC_008009  Acid345_2985  putative anti-sigma regulatory factor, serine/threonine protein kinase  29.89 
 
 
321 aa  42.4  0.002  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.369432  normal 
 
 
-
 
NC_009430  Rsph17025_4164  hypothetical protein  30.28 
 
 
344 aa  42.4  0.002  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_1677  signal transduction histidine kinase  32.79 
 
 
840 aa  42.4  0.002  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_4695  signal transduction histidine kinase  32.17 
 
 
364 aa  42.4  0.002  Methylobacterium populi BJ001  Bacteria  normal  0.910371  normal  0.12529 
 
 
-
 
NC_011894  Mnod_7100  signal transduction histidine kinase  34.94 
 
 
357 aa  42.4  0.002  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_011989  Avi_0384  two component sensor kinase  40.91 
 
 
344 aa  42.4  0.002  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_014148  Plim_2056  anti-sigma regulatory factor  31.25 
 
 
143 aa  42.7  0.002  Planctomyces limnophilus DSM 3776  Bacteria  normal  0.773482  n/a   
 
 
-
 
NC_009485  BBta_1753  sensor histidine kinase  31.71 
 
 
364 aa  42  0.003  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.405521 
 
 
-
 
NC_010511  M446_5174  histidine kinase  26.43 
 
 
273 aa  42  0.003  Methylobacterium sp. 4-46  Bacteria  normal  0.544896  normal  0.227088 
 
 
-
 
NC_010725  Mpop_5039  signal transduction histidine kinase  37.5 
 
 
381 aa  42  0.003  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_013223  Dret_1522  putative anti-sigma regulatory factor, serine/threonine protein kinase  29.01 
 
 
147 aa  42  0.003  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_007958  RPD_3015  histidine kinase, dimerisation/phosphoacceptor  39.62 
 
 
366 aa  41.2  0.004  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal 
 
 
-
 
NC_009621  Smed_5742  signal transduction histidine kinase  43.18 
 
 
398 aa  41.6  0.004  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_4100  putative anti-sigma regulatory factor, serine/threonine protein kinase  30.59 
 
 
154 aa  41.6  0.004  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.39959  normal  0.110814 
 
 
-
 
NC_010172  Mext_4182  histidine kinase dimerisation/phosphoacceptor  35.21 
 
 
338 aa  41.6  0.004  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_2079  putative anti-sigma regulatory factor, serine/threonine protein kinase  24.43 
 
 
152 aa  41.6  0.004  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  0.000225228 
 
 
-
 
NC_011757  Mchl_4553  signal transduction histidine kinase  35.21 
 
 
351 aa  41.6  0.004  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.486913 
 
 
-
 
NC_010172  Mext_4526  histidine kinase dimerisation/phosphoacceptor  34.95 
 
 
381 aa  41.2  0.005  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.315667 
 
 
-
 
NC_011757  Mchl_4986  signal transduction histidine kinase  34.95 
 
 
381 aa  41.2  0.005  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.196103 
 
 
-
 
NC_013721  HMPREF0424_0585  sensor histidine kinase/response regulator  39.58 
 
 
494 aa  41.2  0.005  Gardnerella vaginalis 409-05  Bacteria  n/a    normal  0.785291 
 
 
-
 
NC_007961  Nham_4618  signal transduction histidine kinase  36.62 
 
 
454 aa  40.8  0.006  Nitrobacter hamburgensis X14  Bacteria  normal  0.723174  n/a   
 
 
-
 
NC_009487  SaurJH9_2102  serine-protein kinase RsbW  23.89 
 
 
159 aa  40.8  0.006  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  0.178488  n/a   
 
 
-
 
NC_009632  SaurJH1_2139  serine-protein kinase RsbW  23.89 
 
 
159 aa  40.8  0.006  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_010501  PputW619_2857  signal transduction histidine kinase  45.45 
 
 
515 aa  40.8  0.006  Pseudomonas putida W619  Bacteria  normal  0.207944  normal  0.114386 
 
 
-
 
NC_009428  Rsph17025_1343  signal transduction histidine kinase  35 
 
 
350 aa  40.8  0.007  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  0.54395  normal 
 
 
-
 
NC_007794  Saro_1237  putative signal transduction histidine kinase  35.06 
 
 
547 aa  40.4  0.008  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  0.232329  n/a   
 
 
-
 
NC_011666  Msil_1390  signal transduction histidine kinase  37.1 
 
 
484 aa  40.4  0.008  Methylocella silvestris BL2  Bacteria  n/a    normal  0.38029 
 
 
-
 
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