More than 300 homologs were found in PanDaTox collection
for query gene Hlac_1208 on replicon NC_012029
Organism: Halorubrum lacusprofundi ATCC 49239



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_012029  Hlac_1208  response regulator receiver protein  100 
 
 
201 aa  392  1e-108  Halorubrum lacusprofundi ATCC 49239  Archaea  unclonable  0.00000000244573  hitchhiker  0.00000595914 
 
 
-
 
NC_013743  Htur_1538  response regulator receiver protein  53.33 
 
 
197 aa  204  6e-52  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_013158  Huta_1858  response regulator receiver protein  57.07 
 
 
193 aa  201  7e-51  Halorhabdus utahensis DSM 12940  Archaea  normal  n/a   
 
 
-
 
NC_013158  Huta_2885  response regulator receiver protein  55.85 
 
 
194 aa  200  9.999999999999999e-51  Halorhabdus utahensis DSM 12940  Archaea  normal  n/a   
 
 
-
 
NC_013202  Hmuk_2545  response regulator receiver protein  58.1 
 
 
194 aa  196  2.0000000000000003e-49  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.0974258  normal  0.215411 
 
 
-
 
NC_013743  Htur_0917  response regulator receiver protein  54.01 
 
 
190 aa  194  5.000000000000001e-49  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_013923  Nmag_3741  response regulator receiver protein  53.44 
 
 
210 aa  194  6e-49  Natrialba magadii ATCC 43099  Archaea  normal  n/a   
 
 
-
 
NC_013922  Nmag_3536  response regulator receiver protein  58.68 
 
 
249 aa  192  4e-48  Natrialba magadii ATCC 43099  Archaea  normal  n/a   
 
 
-
 
NC_013202  Hmuk_1750  response regulator receiver protein  53.72 
 
 
212 aa  186  2e-46  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.425063  normal  0.505119 
 
 
-
 
NC_013202  Hmuk_1664  response regulator receiver protein  51.09 
 
 
193 aa  175  5e-43  Halomicrobium mukohataei DSM 12286  Archaea  normal  normal 
 
 
-
 
NC_013202  Hmuk_1584  response regulator receiver protein  48.45 
 
 
197 aa  172  1.9999999999999998e-42  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.449459  normal 
 
 
-
 
NC_012029  Hlac_2553  response regulator receiver protein  50 
 
 
187 aa  168  5e-41  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  0.165021  normal 
 
 
-
 
NC_013202  Hmuk_2371  response regulator receiver protein  52.15 
 
 
182 aa  166  2.9999999999999998e-40  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.263343  normal 
 
 
-
 
NC_013158  Huta_1770  response regulator receiver protein  54.32 
 
 
183 aa  162  3e-39  Halorhabdus utahensis DSM 12940  Archaea  normal  n/a   
 
 
-
 
NC_012029  Hlac_2012  response regulator receiver protein  50 
 
 
186 aa  162  4.0000000000000004e-39  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  normal 
 
 
-
 
NC_013743  Htur_1264  response regulator receiver protein  47.12 
 
 
190 aa  154  9e-37  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_013158  Huta_0359  response regulator receiver protein  51.79 
 
 
183 aa  154  1e-36  Halorhabdus utahensis DSM 12940  Archaea  normal  0.579751  n/a   
 
 
-
 
NC_013158  Huta_1773  response regulator receiver protein  47.25 
 
 
204 aa  139  1.9999999999999998e-32  Halorhabdus utahensis DSM 12940  Archaea  normal  n/a   
 
 
-
 
NC_013202  Hmuk_1875  response regulator receiver protein  48.37 
 
 
189 aa  135  5e-31  Halomicrobium mukohataei DSM 12286  Archaea  normal  normal  0.206239 
 
 
-
 
NC_013743  Htur_2134  response regulator receiver protein  45.81 
 
 
175 aa  130  9e-30  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_013202  Hmuk_2559  response regulator receiver protein  44.05 
 
 
197 aa  130  2.0000000000000002e-29  Halomicrobium mukohataei DSM 12286  Archaea  normal  normal  0.213009 
 
 
-
 
NC_013202  Hmuk_1820  response regulator receiver protein  44.89 
 
 
211 aa  124  1e-27  Halomicrobium mukohataei DSM 12286  Archaea  normal  normal 
 
 
-
 
NC_013158  Huta_1740  response regulator receiver protein  43.95 
 
 
191 aa  110  2.0000000000000002e-23  Halorhabdus utahensis DSM 12940  Archaea  normal  n/a   
 
 
-
 
NC_013158  Huta_0772  response regulator receiver protein  37.27 
 
 
200 aa  97.1  1e-19  Halorhabdus utahensis DSM 12940  Archaea  normal  0.315387  n/a   
 
 
-
 
NC_010814  Glov_1988  response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor  32.83 
 
 
435 aa  80.9  0.00000000000001  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007969  Pcryo_2468  PAS/PAC sensor hybrid histidine kinase  36.97 
 
 
974 aa  73.9  0.000000000002  Psychrobacter cryohalolentis K5  Bacteria  normal  normal  0.0515999 
 
 
-
 
NC_009767  Rcas_1114  response regulator receiver modulated serine phosphatase  40.62 
 
 
391 aa  72.8  0.000000000003  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_011004  Rpal_2612  two component transcriptional regulator, winged helix family  40.16 
 
 
228 aa  72  0.000000000005  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.0412974  n/a   
 
 
-
 
NC_009523  RoseRS_3770  response regulator receiver protein  39.06 
 
 
391 aa  71.2  0.000000000009  Roseiflexus sp. RS-1  Bacteria  normal  unclonable  0.0000112062 
 
 
-
 
NC_010002  Daci_0123  two component transcriptional regulator  42.62 
 
 
241 aa  70.9  0.00000000001  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_5742  two component transcriptional regulator  42.02 
 
 
342 aa  70.1  0.00000000002  Delftia acidovorans SPH-1  Bacteria  normal  0.0760421  hitchhiker  0.00137021 
 
 
-
 
NC_007643  Rru_A2929  two component transcriptional regulator  43.2 
 
 
250 aa  70.1  0.00000000002  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.449606  n/a   
 
 
-
 
NC_011831  Cagg_1830  response regulator receiver modulated diguanylate cyclase  41.28 
 
 
941 aa  70.1  0.00000000002  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_010424  Daud_0677  response regulator receiver modulated metal dependent phosphohydrolase  32.12 
 
 
343 aa  70.5  0.00000000002  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.756866  n/a   
 
 
-
 
NC_008752  Aave_4321  two component transcriptional regulator  42.37 
 
 
248 aa  70.1  0.00000000002  Acidovorax citrulli AAC00-1  Bacteria  normal  normal  0.173505 
 
 
-
 
NC_003910  CPS_1426  transcriptional regulatory protein RstA  37.9 
 
 
248 aa  69.7  0.00000000003  Colwellia psychrerythraea 34H  Bacteria  normal  0.319576  n/a   
 
 
-
 
NC_013171  Apre_1215  two component transcriptional regulator, winged helix family  36.67 
 
 
237 aa  69.7  0.00000000003  Anaerococcus prevotii DSM 20548  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_0671  two component, sigma54 specific, transcriptional regulator, Fis family  41.59 
 
 
469 aa  69.7  0.00000000003  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_0304  response regulator receiver protein  43.22 
 
 
218 aa  69.3  0.00000000004  Streptosporangium roseum DSM 43021  Bacteria  normal  0.818258  normal 
 
 
-
 
NC_013411  GYMC61_2718  two component transcriptional regulator, AraC family  37.61 
 
 
259 aa  68.6  0.00000000006  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_012917  PC1_2692  two component transcriptional regulator, winged helix family  38.84 
 
 
229 aa  67.8  0.0000000001  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  n/a   
 
 
-
 
NC_011071  Smal_1792  two component transcriptional regulator, winged helix family  42.02 
 
 
249 aa  67.4  0.0000000001  Stenotrophomonas maltophilia R551-3  Bacteria  normal  0.783202  normal  0.482984 
 
 
-
 
NC_009523  RoseRS_0338  response regulator receiver modulated metal dependent phosphohydrolase  33.51 
 
 
513 aa  67.8  0.0000000001  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.102838 
 
 
-
 
NC_012912  Dd1591_2774  two component transcriptional regulator, winged helix family  37.8 
 
 
245 aa  66.6  0.0000000002  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_009438  Sputcn32_3972  two component transcriptional regulator  37.8 
 
 
242 aa  66.6  0.0000000002  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_2724  response regulator receiver domain-containing protein  36.43 
 
 
230 aa  67  0.0000000002  Saccharophagus degradans 2-40  Bacteria  normal  0.480114  normal 
 
 
-
 
NC_012918  GM21_0684  two component, sigma54 specific, transcriptional regulator, Fis family  39.82 
 
 
469 aa  67  0.0000000002  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.0000000000150794 
 
 
-
 
NC_003296  RS05454  two component response regulator transcription regulator protein  37.9 
 
 
256 aa  66.2  0.0000000003  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.169333 
 
 
-
 
NC_007298  Daro_0007  response regulator receiver modulated metal dependent phosphohydrolase  30.48 
 
 
379 aa  66.2  0.0000000003  Dechloromonas aromatica RCB  Bacteria  normal  0.829613  normal  0.0284762 
 
 
-
 
NC_009674  Bcer98_1815  two component transcriptional regulator  32.72 
 
 
232 aa  66.2  0.0000000003  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.101184  n/a   
 
 
-
 
NC_013170  Ccur_11690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  38.35 
 
 
236 aa  65.9  0.0000000003  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.52451  normal 
 
 
-
 
NC_013131  Caci_0208  two component transcriptional regulator, winged helix family  41.86 
 
 
238 aa  66.2  0.0000000003  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_007511  Bcep18194_B3050  two component transcriptional regulator  36.72 
 
 
245 aa  65.5  0.0000000005  Burkholderia sp. 383  Bacteria  normal  0.545982  normal 
 
 
-
 
NC_013440  Hoch_6002  two component transcriptional regulator, winged helix family  42.62 
 
 
243 aa  65.5  0.0000000005  Haliangium ochraceum DSM 14365  Bacteria  normal  0.472724  normal 
 
 
-
 
NC_010718  Nther_0252  response regulator receiver protein  35.59 
 
 
239 aa  65.5  0.0000000006  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal  0.114255 
 
 
-
 
NC_008752  Aave_2526  two component transcriptional regulator  40.34 
 
 
262 aa  65.5  0.0000000006  Acidovorax citrulli AAC00-1  Bacteria  normal  0.262723  normal  0.926116 
 
 
-
 
NC_009524  PsycPRwf_2160  two component transcriptional regulator  35.88 
 
 
240 aa  65.1  0.0000000007  Psychrobacter sp. PRwf-1  Bacteria  normal  normal 
 
 
-
 
NC_008061  Bcen_5049  two component transcriptional regulator  35.94 
 
 
259 aa  65.1  0.0000000007  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.839238  n/a   
 
 
-
 
NC_013204  Elen_0258  two component transcriptional regulator, winged helix family  37.59 
 
 
236 aa  64.7  0.0000000008  Eggerthella lenta DSM 2243  Bacteria  normal  0.606292  normal 
 
 
-
 
NC_010515  Bcenmc03_4368  two component transcriptional regulator  35.94 
 
 
245 aa  64.7  0.0000000008  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal 
 
 
-
 
NC_008543  Bcen2424_5811  two component transcriptional regulator  35.94 
 
 
245 aa  64.7  0.0000000008  Burkholderia cenocepacia HI2424  Bacteria  normal  0.244111  normal 
 
 
-
 
NC_003909  BCE_2564  DNA-binding response regulator  33.33 
 
 
231 aa  64.3  0.000000001  Bacillus cereus ATCC 10987  Bacteria  normal  0.0589521  n/a   
 
 
-
 
NC_011725  BCB4264_A2526  DNA-binding response regulator  32.1 
 
 
231 aa  64.3  0.000000001  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS2385  DNA-binding response regulator  33.33 
 
 
231 aa  64.3  0.000000001  Bacillus anthracis str. Sterne  Bacteria  normal  0.534853  n/a   
 
 
-
 
NC_005957  BT9727_2341  DNA-binding response regulator  33.33 
 
 
231 aa  64.3  0.000000001  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.000000166477  n/a   
 
 
-
 
NC_006274  BCZK2302  DNA-binding response regulator  33.33 
 
 
231 aa  64.3  0.000000001  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_009511  Swit_1954  two component transcriptional regulator  44.66 
 
 
253 aa  64.7  0.000000001  Sphingomonas wittichii RW1  Bacteria  normal  0.897911  normal 
 
 
-
 
NC_007512  Plut_1258  two component Fis family transcriptional regulator  32.07 
 
 
486 aa  63.9  0.000000001  Chlorobium luteolum DSM 273  Bacteria  normal  normal 
 
 
-
 
NC_007530  GBAA_2561  DNA-binding response regulator  33.33 
 
 
231 aa  64.3  0.000000001  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.630654  n/a   
 
 
-
 
NC_007955  Mbur_0878  response regulator receiver  34.39 
 
 
302 aa  63.9  0.000000001  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_011773  BCAH820_2574  DNA-binding response regulator  33.33 
 
 
231 aa  64.3  0.000000001  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  0.00000000000040017 
 
 
-
 
NC_013165  Shel_00330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  38.89 
 
 
240 aa  64.3  0.000000001  Slackia heliotrinireducens DSM 20476  Bacteria  decreased coverage  0.00972196  normal 
 
 
-
 
NC_011772  BCG9842_B2796  DNA-binding response regulator  32.1 
 
 
231 aa  64.3  0.000000001  Bacillus cereus G9842  Bacteria  normal  0.512352  hitchhiker  0.00000533196 
 
 
-
 
NC_009486  Tpet_0521  two component transcriptional regulator  40.68 
 
 
223 aa  63.9  0.000000001  Thermotoga petrophila RKU-1  Bacteria  normal  0.720367  n/a   
 
 
-
 
NC_009076  BURPS1106A_0042  DNA-binding response regulator  40.68 
 
 
225 aa  63.5  0.000000002  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  38.93 
 
 
226 aa  63.9  0.000000002  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_006348  BMA2676  DNA-binding response regulator  40.68 
 
 
225 aa  63.5  0.000000002  Burkholderia mallei ATCC 23344  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1181  two component transcriptional regulator, winged helix family  39.17 
 
 
234 aa  63.5  0.000000002  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.00335068 
 
 
-
 
NC_007434  BURPS1710b_0255  DNA-binding response regulator  40.68 
 
 
225 aa  63.5  0.000000002  Burkholderia pseudomallei 1710b  Bacteria  normal  n/a   
 
 
-
 
NC_010086  Bmul_4353  two component transcriptional regulator  37.82 
 
 
245 aa  63.5  0.000000002  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_007651  BTH_I0039  DNA-binding response regulator  40.68 
 
 
225 aa  63.5  0.000000002  Burkholderia thailandensis E264  Bacteria  normal  n/a   
 
 
-
 
NC_007925  RPC_2735  two component transcriptional regulator  40.34 
 
 
228 aa  63.5  0.000000002  Rhodopseudomonas palustris BisB18  Bacteria  normal  normal  0.223671 
 
 
-
 
NC_013159  Svir_02690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  40.34 
 
 
229 aa  63.9  0.000000002  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_009080  BMA10247_2701  DNA-binding response regulator  40.68 
 
 
225 aa  63.5  0.000000002  Burkholderia mallei NCTC 10247  Bacteria  normal  n/a   
 
 
-
 
NC_009074  BURPS668_0042  DNA-binding response regulator  40.68 
 
 
225 aa  63.5  0.000000002  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A2617  DNA-binding response regulator  32.72 
 
 
231 aa  63.9  0.000000002  Bacillus cereus AH187  Bacteria  normal  0.993672  n/a   
 
 
-
 
NC_011059  Paes_0769  two component transcriptional regulator, winged helix family  36.62 
 
 
236 aa  63.5  0.000000002  Prosthecochloris aestuarii DSM 271  Bacteria  normal  normal 
 
 
-
 
NC_013061  Phep_2824  ATP-binding region ATPase domain protein  27.55 
 
 
1374 aa  63.2  0.000000002  Pedobacter heparinus DSM 2366  Bacteria  normal  normal 
 
 
-
 
NC_008785  BMASAVP1_A3276  DNA-binding response regulator  40.68 
 
 
225 aa  63.5  0.000000002  Burkholderia mallei SAVP1  Bacteria  normal  n/a   
 
 
-
 
NC_008836  BMA10229_A1851  DNA-binding response regulator  40.68 
 
 
225 aa  63.5  0.000000002  Burkholderia mallei NCTC 10229  Bacteria  normal  n/a   
 
 
-
 
NC_013922  Nmag_2044  transcriptional regulator, HxlR family  32.16 
 
 
357 aa  63.2  0.000000003  Natrialba magadii ATCC 43099  Archaea  normal  n/a   
 
 
-
 
NC_013441  Gbro_1324  response regulator receiver  38.14 
 
 
223 aa  62.8  0.000000003  Gordonia bronchialis DSM 43247  Bacteria  normal  0.88989  n/a   
 
 
-
 
NC_011772  BCG9842_B4731  DNA-binding response regulator  36.22 
 
 
223 aa  63.2  0.000000003  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_0961  response regulator receiver protein  39.83 
 
 
229 aa  63.2  0.000000003  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_007955  Mbur_1899  multisensor signal transduction histidine kinase  36.64 
 
 
462 aa  63.2  0.000000003  Methanococcoides burtonii DSM 6242  Archaea  normal  0.970297  n/a   
 
 
-
 
NC_011898  Ccel_1714  two component transcriptional regulator, winged helix family  32 
 
 
234 aa  62.8  0.000000003  Clostridium cellulolyticum H10  Bacteria  normal  0.233786  n/a   
 
 
-
 
NC_010180  BcerKBAB4_5471  two component transcriptional regulator  34.45 
 
 
221 aa  62.8  0.000000003  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.00800002  hitchhiker  0.0013378 
 
 
-
 
NC_013440  Hoch_0018  two component, sigma54 specific, transcriptional regulator, Fis family  36.72 
 
 
461 aa  62.8  0.000000003  Haliangium ochraceum DSM 14365  Bacteria  normal  0.709029  normal  0.924426 
 
 
-
 
NC_011725  BCB4264_A0608  DNA-binding response regulator  36.22 
 
 
223 aa  63.2  0.000000003  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_2845  two component transcriptional regulator, winged helix family  34.19 
 
 
234 aa  62.8  0.000000004  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
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