More than 300 homologs were found in PanDaTox collection
for query gene Dfer_5176 on replicon NC_013037
Organism: Dyadobacter fermentans DSM 18053



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009621  Smed_5776  putative PAS/PAC sensor protein  42.53 
 
 
1160 aa  681    Sinorhizobium medicae WSM419  Bacteria  normal  0.491611  normal  0.0137055 
 
 
-
 
NC_007348  Reut_B4915  PAS  47.47 
 
 
1384 aa  857    Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_010580  Bind_3835  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  39.98 
 
 
1167 aa  690    Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_010625  Bphy_6399  signal transduction histidine kinase with CheB and CheR activity  47.61 
 
 
1361 aa  855    Burkholderia phymatum STM815  Bacteria  normal  0.191888  normal 
 
 
-
 
NC_013037  Dfer_5571  signal transduction histidine kinase with CheB and CheR activity  65.9 
 
 
1218 aa  1116    Dyadobacter fermentans DSM 18053  Bacteria  normal  0.273526  normal 
 
 
-
 
NC_010322  PputGB1_3018  signal transduction histidine kinase with CheB and CheR activity  43.1 
 
 
1371 aa  775    Pseudomonas putida GB-1  Bacteria  normal  normal  0.980757 
 
 
-
 
NC_013037  Dfer_5176  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  100 
 
 
1404 aa  2878    Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.190634 
 
 
-
 
NC_013132  Cpin_4422  signal transduction histidine kinase with CheB and CheR activity  55.79 
 
 
1274 aa  1031    Chitinophaga pinensis DSM 2588  Bacteria  normal  0.381764  normal 
 
 
-
 
NC_010086  Bmul_3193  signal transduction histidine kinase with CheB and CheR activity  41.92 
 
 
1380 aa  768    Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.112764 
 
 
-
 
NC_008752  Aave_2417  signal transduction histidine kinase with CheB and CheR activity  42.05 
 
 
1535 aa  768    Acidovorax citrulli AAC00-1  Bacteria  normal  0.117494  normal 
 
 
-
 
NC_008781  Pnap_1703  signal transduction histidine kinase with CheB and CheR activity  46.26 
 
 
1408 aa  850    Polaromonas naphthalenivorans CJ2  Bacteria  normal  0.433463  normal 
 
 
-
 
NC_009712  Mboo_0327  putative PAS/PAC sensor protein  37.98 
 
 
1008 aa  633  1e-180  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal 
 
 
-
 
NC_007484  Noc_1601  CheB methylesterase, CheR methyltransferase, hybrid histidine kinase  41 
 
 
1222 aa  629  1e-178  Nitrosococcus oceani ATCC 19707  Bacteria  normal  0.472526  n/a   
 
 
-
 
NC_007908  Rfer_2355  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  39.96 
 
 
1008 aa  625  1e-177  Rhodoferax ferrireducens T118  Bacteria  normal  0.71741  n/a   
 
 
-
 
NC_007355  Mbar_A2183  hypothetical protein  39.23 
 
 
980 aa  614  9.999999999999999e-175  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal  0.850093 
 
 
-
 
NC_011060  Ppha_0229  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  36.05 
 
 
1138 aa  602  1e-170  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  n/a   
 
 
-
 
NC_011060  Ppha_1653  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  37.1 
 
 
993 aa  595  1e-168  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  n/a   
 
 
-
 
NC_010803  Clim_1600  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  36.14 
 
 
1000 aa  595  1e-168  Chlorobium limicola DSM 245  Bacteria  normal  n/a   
 
 
-
 
NC_008639  Cpha266_1788  putative PAS/PAC sensor protein  38.27 
 
 
998 aa  595  1e-168  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  n/a   
 
 
-
 
NC_007514  Cag_0563  putative PAS/PAC sensor protein  37.02 
 
 
1035 aa  590  1e-167  Chlorobium chlorochromatii CaD3  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_3183  signal transduction histidine kinase  40.74 
 
 
1279 aa  590  1e-167  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_2162  MCP methyltransferase/methylesterase, CheR/CheB  39.31 
 
 
879 aa  590  1e-167  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_3377  signal transduction histidine kinase with CheB and CheR activity  40.98 
 
 
1242 aa  588  1e-166  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_010725  Mpop_1297  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  37.99 
 
 
1168 aa  584  1.0000000000000001e-165  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_009620  Smed_4278  putative PAS/PAC sensor protein  39.25 
 
 
1027 aa  580  1e-164  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_007517  Gmet_0780  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  38.9 
 
 
887 aa  578  1.0000000000000001e-163  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_007298  Daro_2045  CheB methylesterase:MCP methyltransferase, CheR-type  39.31 
 
 
868 aa  571  1e-161  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007908  Rfer_3013  MCP methyltransferase, CheR-type  38.66 
 
 
877 aa  570  1e-161  Rhodoferax ferrireducens T118  Bacteria  normal  0.404945  n/a   
 
 
-
 
NC_010581  Bind_0707  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  36.34 
 
 
1190 aa  572  1e-161  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_011145  AnaeK_0372  signal transduction histidine kinase with CheB and CheR activity  40.29 
 
 
1233 aa  565  1.0000000000000001e-159  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_011832  Mpal_2460  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  38.04 
 
 
971 aa  566  1.0000000000000001e-159  Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_007413  Ava_0314  Signal transduction histidine kinase (STHK) with CheB and CheR activity  38.28 
 
 
1399 aa  561  1e-158  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_014248  Aazo_2376  signal transduction histidine kinase with CheB and CheR activity  35.08 
 
 
1407 aa  560  1e-158  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_013205  Aaci_0673  signal transduction histidine kinase with CheB and CheR activity  33.98 
 
 
1215 aa  557  1e-157  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_6211  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  41.12 
 
 
1061 aa  559  1e-157  Methylobacterium sp. 4-46  Bacteria  normal  0.820077  normal  0.703655 
 
 
-
 
NC_009467  Acry_3169  signal transduction histidine kinase with CheB and CheR activity  39.14 
 
 
1445 aa  552  1e-155  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_007643  Rru_A1500  Signal transduction histidine kinase (STHK) with CheB and CheR activity  38.41 
 
 
1483 aa  553  1e-155  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_008709  Ping_2549  fused CheR-type MCP methyltransferase and PAS sensor protein  35.35 
 
 
1006 aa  551  1e-155  Psychromonas ingrahamii 37  Bacteria  normal  normal 
 
 
-
 
NC_007961  Nham_4605  MCP methyltransferase, CheR-type  38.51 
 
 
1092 aa  549  1e-154  Nitrobacter hamburgensis X14  Bacteria  normal  0.315944  n/a   
 
 
-
 
NC_010510  Mrad2831_6264  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  38.21 
 
 
1163 aa  546  1e-153  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_3250  signal transduction histidine kinase with CheB and CheR activity  34.21 
 
 
1348 aa  544  1e-153  Haliangium ochraceum DSM 14365  Bacteria  normal  0.534329  normal  0.0270765 
 
 
-
 
NC_008709  Ping_1840  MCP methyltransferase, CheR-type  38.01 
 
 
840 aa  546  1e-153  Psychromonas ingrahamii 37  Bacteria  normal  0.59391  normal  0.603716 
 
 
-
 
NC_008709  Ping_3128  MCP methyltransferase, CheR-type  37.93 
 
 
840 aa  542  9.999999999999999e-153  Psychromonas ingrahamii 37  Bacteria  normal  normal 
 
 
-
 
NC_011368  Rleg2_5237  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  34.3 
 
 
1324 aa  538  1e-151  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.395635 
 
 
-
 
NC_008340  Mlg_1118  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  38.06 
 
 
852 aa  538  1e-151  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  normal  0.742809 
 
 
-
 
NC_013173  Dbac_1410  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  32.62 
 
 
1120 aa  536  1e-150  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.132886  n/a   
 
 
-
 
NC_011004  Rpal_3739  MCP methyltransferase, CheR-type  39.29 
 
 
1045 aa  528  1e-148  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_008789  Hhal_1716  MCP methyltransferase, CheR-type  38.48 
 
 
856 aa  528  1e-148  Halorhodospira halophila SL1  Bacteria  normal  0.92135  n/a   
 
 
-
 
NC_007953  Bxe_C0521  multi sensor hybrid histidine kinase  36.27 
 
 
1344 aa  516  1e-144  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_011894  Mnod_3755  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  40.85 
 
 
1063 aa  504  1e-141  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_007952  Bxe_B1520  signal transduction histidine kinase (STHK) with CheB and CheR activity  36.45 
 
 
1303 aa  501  1e-140  Burkholderia xenovorans LB400  Bacteria  normal  0.124967  normal 
 
 
-
 
NC_008609  Ppro_3165  signal transduction histidine kinase with CheB and CheR activity  35.58 
 
 
1306 aa  493  9.999999999999999e-139  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_013440  Hoch_4639  signal transduction histidine kinase with CheB and CheR activity  32.16 
 
 
1453 aa  491  1e-137  Haliangium ochraceum DSM 14365  Bacteria  normal  0.432269  normal 
 
 
-
 
NC_007912  Sde_3046  hypothetical protein  35.73 
 
 
1010 aa  488  1e-136  Saccharophagus degradans 2-40  Bacteria  normal  hitchhiker  0.00164382 
 
 
-
 
NC_013132  Cpin_7206  signal transduction histidine kinase with CheB and CheR activity  31.9 
 
 
1499 aa  487  1e-136  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_0310  MCP methyltransferase, CheR-type  36.12 
 
 
1149 aa  486  1e-135  Methylobacterium populi BJ001  Bacteria  normal  0.512157  normal 
 
 
-
 
NC_010505  Mrad2831_4430  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  35.4 
 
 
1158 aa  479  1e-133  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_007493  RSP_2229  methylesterase CheB/methylase CheR  34.56 
 
 
1170 aa  473  1e-132  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  0.840236  n/a   
 
 
-
 
NC_009049  Rsph17029_0905  putative PAS/PAC sensor protein  34.56 
 
 
1170 aa  473  1.0000000000000001e-131  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  normal  0.968727 
 
 
-
 
NC_010505  Mrad2831_5709  MCP methyltransferase, CheR-type  36.06 
 
 
853 aa  469  9.999999999999999e-131  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.729466 
 
 
-
 
NC_013061  Phep_3913  PAS sensor protein  34.27 
 
 
1337 aa  463  1e-129  Pedobacter heparinus DSM 2366  Bacteria  normal  0.290527  normal  0.28306 
 
 
-
 
NC_014230  CA2559_12648  Signal Transduction Histidine Kinase (STHK) with CheB and CheRactivity  32.43 
 
 
1200 aa  461  9.999999999999999e-129  Croceibacter atlanticus HTCC2559  Bacteria  normal  n/a   
 
 
-
 
NC_009428  Rsph17025_2264  putative PAS/PAC sensor protein  34.26 
 
 
1165 aa  461  9.999999999999999e-129  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  0.620072  normal  0.0600346 
 
 
-
 
NC_007955  Mbur_0399  MCP methyltransferase, CheR-type  33.01 
 
 
820 aa  458  1e-127  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_013730  Slin_3102  signal transduction histidine kinase with CheB and CheR activity  33.23 
 
 
1418 aa  455  1.0000000000000001e-126  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_3278  signal transduction histidine kinase with CheB and CheR activity  34.01 
 
 
2468 aa  456  1.0000000000000001e-126  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.0267066 
 
 
-
 
NC_002977  MCA1246  methyltransferase CheR, putative  33.94 
 
 
1378 aa  443  9.999999999999999e-123  Methylococcus capsulatus str. Bath  Bacteria  normal  0.271052  n/a   
 
 
-
 
NC_013440  Hoch_1404  signal transduction histidine kinase with CheB and CheR activity  29.55 
 
 
1759 aa  442  9.999999999999999e-123  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_5252  signal transduction histidine kinase with CheB and CheR activity  33.45 
 
 
1698 aa  437  1e-121  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_008751  Dvul_2487  signal transduction histidine kinase with CheB and CheR activity  31.57 
 
 
1535 aa  439  1e-121  Desulfovibrio vulgaris DP4  Bacteria  normal  0.162467  normal  0.455724 
 
 
-
 
NC_008255  CHU_1237  chemotaxis response regulator (methyltransferase)  32.87 
 
 
1618 aa  425  1e-117  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  normal 
 
 
-
 
NC_010086  Bmul_4696  signal transduction histidine kinase with CheB and CheR activity  35.34 
 
 
1214 aa  412  1e-113  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_008789  Hhal_0370  protein-glutamate O-methyltransferase  39.12 
 
 
639 aa  403  9.999999999999999e-111  Halorhodospira halophila SL1  Bacteria  normal  0.181962  n/a   
 
 
-
 
NC_010508  Bcenmc03_1302  signal transduction histidine kinase with CheB and CheR activity  33.62 
 
 
1220 aa  395  1e-108  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.772751 
 
 
-
 
NC_008044  TM1040_1028  signal transduction histidine kinase with CheB and CheR activity  32.28 
 
 
1248 aa  389  1e-106  Ruegeria sp. TM1040  Bacteria  normal  normal  0.507304 
 
 
-
 
NC_009622  Smed_6341  putative PAS/PAC sensor protein  40.15 
 
 
629 aa  373  1e-101  Sinorhizobium medicae WSM419  Bacteria  normal  0.433344  normal  0.230755 
 
 
-
 
NC_007802  Jann_2564  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  30.37 
 
 
1089 aa  364  6e-99  Jannaschia sp. CCS1  Bacteria  normal  normal 
 
 
-
 
NC_007348  Reut_B5191  CheB methylesterase:MCP methyltransferase, CheR-type  30.24 
 
 
813 aa  362  3e-98  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_008044  TM1040_0460  MCP methyltransferase, CheR-type  33.87 
 
 
837 aa  361  5e-98  Ruegeria sp. TM1040  Bacteria  normal  0.604812  normal 
 
 
-
 
NC_013730  Slin_1989  MCP methyltransferase, CheR-type with PAS/PAC sensor  30.2 
 
 
1110 aa  358  2.9999999999999997e-97  Spirosoma linguale DSM 74  Bacteria  normal  0.175442  normal  0.013335 
 
 
-
 
NC_008576  Mmc1_3390  MCP methyltransferase, CheR-type  34.24 
 
 
617 aa  357  1e-96  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_010814  Glov_0566  MCP methyltransferase, CheR-type with PAS/PAC sensor  31.98 
 
 
1193 aa  343  1e-92  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_008044  TM1040_2227  MCP methyltransferase, CheR-type  31.68 
 
 
824 aa  343  2e-92  Ruegeria sp. TM1040  Bacteria  normal  normal 
 
 
-
 
NC_010623  Bphy_5175  MCP methyltransferase, CheR-type  29.18 
 
 
823 aa  339  2.9999999999999997e-91  Burkholderia phymatum STM815  Bacteria  normal  normal  0.367936 
 
 
-
 
NC_010814  Glov_2975  diguanylate cyclase with PAS/PAC sensor  32.08 
 
 
1084 aa  339  2.9999999999999997e-91  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_013132  Cpin_3640  MCP methyltransferase, CheR-type with PAS/PAC sensor  30.38 
 
 
1303 aa  320  1e-85  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal  0.581797 
 
 
-
 
NC_007964  Nham_3990  MCP methyltransferase, CheR-type  42.67 
 
 
432 aa  318  3e-85  Nitrobacter hamburgensis X14  Bacteria  normal  n/a   
 
 
-
 
NC_010717  PXO_03023  methyltransferase  34.33 
 
 
604 aa  305  5.000000000000001e-81  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.361036  n/a   
 
 
-
 
NC_013440  Hoch_3427  MCP methyltransferase, CheR-type with PAS/PAC sensor  27.43 
 
 
2031 aa  239  3e-61  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.0889636 
 
 
-
 
NC_014248  Aazo_0227  MCP methyltransferase  29.38 
 
 
631 aa  237  2.0000000000000002e-60  'Nostoc azollae' 0708  Bacteria  normal  0.993793  n/a   
 
 
-
 
NC_011884  Cyan7425_3121  MCP methyltransferase, CheR-type with PAS/PAC sensor  30.9 
 
 
617 aa  224  8e-57  Cyanothece sp. PCC 7425  Bacteria  normal  0.0152355  normal  0.805919 
 
 
-
 
NC_011729  PCC7424_0433  MCP methyltransferase, CheR-type with PAS/PAC sensor  29.63 
 
 
618 aa  216  1.9999999999999998e-54  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_010725  Mpop_0172  signal transduction histidine kinase  27.99 
 
 
897 aa  184  1e-44  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_011884  Cyan7425_2234  signal transduction histidine kinase  27.17 
 
 
1676 aa  176  2.9999999999999996e-42  Cyanothece sp. PCC 7425  Bacteria  normal  normal  0.900765 
 
 
-
 
NC_010510  Mrad2831_6181  signal transduction histidine kinase  27.62 
 
 
1191 aa  174  1e-41  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.299797 
 
 
-
 
NC_008576  Mmc1_3393  putative PAS/PAC sensor protein  29.09 
 
 
545 aa  171  9e-41  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_011894  Mnod_6615  PAS/PAC sensor hybrid histidine kinase  36.95 
 
 
660 aa  170  2e-40  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.0224174  n/a   
 
 
-
 
NC_009483  Gura_1221  PAS/PAC sensor signal transduction histidine kinase  34.72 
 
 
637 aa  163  2e-38  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_008254  Meso_1904  PAS/PAC sensor hybrid histidine kinase  34.15 
 
 
651 aa  163  2e-38  Chelativorans sp. BNC1  Bacteria  normal  0.326262  n/a   
 
 
-
 
NC_010718  Nther_1604  MCP methyltransferase, CheR-type  35.44 
 
 
260 aa  162  5e-38  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  0.0143514  unclonable  1.76137e-23 
 
 
-
 
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