More than 300 homologs were found in PanDaTox collection
for query gene Daro_2045 on replicon NC_007298
Organism: Dechloromonas aromatica RCB



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011060  Ppha_0229  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  58.55 
 
 
1138 aa  959    Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  n/a   
 
 
-
 
NC_010625  Bphy_6399  signal transduction histidine kinase with CheB and CheR activity  40 
 
 
1361 aa  648    Burkholderia phymatum STM815  Bacteria  normal  0.191888  normal 
 
 
-
 
NC_013173  Dbac_2162  MCP methyltransferase/methylesterase, CheR/CheB  59.62 
 
 
879 aa  1003    Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_2045  CheB methylesterase:MCP methyltransferase, CheR-type  100 
 
 
868 aa  1784    Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007355  Mbar_A2183  hypothetical protein  43.19 
 
 
980 aa  696    Methanosarcina barkeri str. Fusaro  Archaea  normal  normal  0.850093 
 
 
-
 
NC_007413  Ava_0314  Signal transduction histidine kinase (STHK) with CheB and CheR activity  41.07 
 
 
1399 aa  648    Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_007514  Cag_0563  putative PAS/PAC sensor protein  55.86 
 
 
1035 aa  909    Chlorobium chlorochromatii CaD3  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_0780  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  57.04 
 
 
887 aa  959    Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_009712  Mboo_0327  putative PAS/PAC sensor protein  49.82 
 
 
1008 aa  799    Candidatus Methanoregula boonei 6A8  Archaea  normal  normal 
 
 
-
 
NC_007908  Rfer_2355  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  47.46 
 
 
1008 aa  738    Rhodoferax ferrireducens T118  Bacteria  normal  0.71741  n/a   
 
 
-
 
NC_007908  Rfer_3013  MCP methyltransferase, CheR-type  55.31 
 
 
877 aa  896    Rhodoferax ferrireducens T118  Bacteria  normal  0.404945  n/a   
 
 
-
 
NC_010803  Clim_1600  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  57.34 
 
 
1000 aa  961    Chlorobium limicola DSM 245  Bacteria  normal  n/a   
 
 
-
 
NC_011060  Ppha_1653  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  57.13 
 
 
993 aa  951    Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  n/a   
 
 
-
 
NC_008340  Mlg_1118  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  50.18 
 
 
852 aa  799    Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  normal  0.742809 
 
 
-
 
NC_008639  Cpha266_1788  putative PAS/PAC sensor protein  57.14 
 
 
998 aa  973    Chlorobium phaeobacteroides DSM 266  Bacteria  normal  n/a   
 
 
-
 
NC_008709  Ping_1840  MCP methyltransferase, CheR-type  58.46 
 
 
840 aa  961    Psychromonas ingrahamii 37  Bacteria  normal  0.59391  normal  0.603716 
 
 
-
 
NC_008709  Ping_2549  fused CheR-type MCP methyltransferase and PAS sensor protein  43.07 
 
 
1006 aa  681    Psychromonas ingrahamii 37  Bacteria  normal  normal 
 
 
-
 
NC_008709  Ping_3128  MCP methyltransferase, CheR-type  58.6 
 
 
840 aa  957    Psychromonas ingrahamii 37  Bacteria  normal  normal 
 
 
-
 
NC_011832  Mpal_2460  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  59.01 
 
 
971 aa  973    Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_014248  Aazo_2376  signal transduction histidine kinase with CheB and CheR activity  40.02 
 
 
1407 aa  630  1e-179  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_008781  Pnap_1703  signal transduction histidine kinase with CheB and CheR activity  40.14 
 
 
1408 aa  626  1e-178  Polaromonas naphthalenivorans CJ2  Bacteria  normal  0.433463  normal 
 
 
-
 
NC_009620  Smed_4278  putative PAS/PAC sensor protein  42.29 
 
 
1027 aa  613  9.999999999999999e-175  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_007348  Reut_B4915  PAS  40.24 
 
 
1384 aa  610  1e-173  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_007643  Rru_A1500  Signal transduction histidine kinase (STHK) with CheB and CheR activity  40.98 
 
 
1483 aa  612  1e-173  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_010581  Bind_0707  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  40.78 
 
 
1190 aa  608  9.999999999999999e-173  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_5571  signal transduction histidine kinase with CheB and CheR activity  39.41 
 
 
1218 aa  605  1.0000000000000001e-171  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.273526  normal 
 
 
-
 
NC_013173  Dbac_1410  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  39.93 
 
 
1120 aa  596  1e-169  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.132886  n/a   
 
 
-
 
NC_007961  Nham_4605  MCP methyltransferase, CheR-type  40.66 
 
 
1092 aa  590  1e-167  Nitrobacter hamburgensis X14  Bacteria  normal  0.315944  n/a   
 
 
-
 
NC_010580  Bind_3835  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  39 
 
 
1167 aa  581  1e-164  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_008789  Hhal_1716  MCP methyltransferase, CheR-type  40.38 
 
 
856 aa  580  1e-164  Halorhodospira halophila SL1  Bacteria  normal  0.92135  n/a   
 
 
-
 
NC_007760  Adeh_3183  signal transduction histidine kinase  40.28 
 
 
1279 aa  582  1e-164  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_008752  Aave_2417  signal transduction histidine kinase with CheB and CheR activity  39.16 
 
 
1535 aa  582  1e-164  Acidovorax citrulli AAC00-1  Bacteria  normal  0.117494  normal 
 
 
-
 
NC_011891  A2cp1_3377  signal transduction histidine kinase with CheB and CheR activity  39.93 
 
 
1242 aa  577  1.0000000000000001e-163  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_009621  Smed_5776  putative PAS/PAC sensor protein  38.61 
 
 
1160 aa  577  1.0000000000000001e-163  Sinorhizobium medicae WSM419  Bacteria  normal  0.491611  normal  0.0137055 
 
 
-
 
NC_009467  Acry_3169  signal transduction histidine kinase with CheB and CheR activity  39.7 
 
 
1445 aa  578  1.0000000000000001e-163  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_010725  Mpop_1297  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  40.72 
 
 
1168 aa  576  1.0000000000000001e-163  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_007484  Noc_1601  CheB methylesterase, CheR methyltransferase, hybrid histidine kinase  40.02 
 
 
1222 aa  575  1.0000000000000001e-162  Nitrosococcus oceani ATCC 19707  Bacteria  normal  0.472526  n/a   
 
 
-
 
NC_010086  Bmul_3193  signal transduction histidine kinase with CheB and CheR activity  37.71 
 
 
1380 aa  574  1.0000000000000001e-162  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.112764 
 
 
-
 
NC_013132  Cpin_4422  signal transduction histidine kinase with CheB and CheR activity  38.32 
 
 
1274 aa  575  1.0000000000000001e-162  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.381764  normal 
 
 
-
 
NC_010322  PputGB1_3018  signal transduction histidine kinase with CheB and CheR activity  39.7 
 
 
1371 aa  571  1e-161  Pseudomonas putida GB-1  Bacteria  normal  normal  0.980757 
 
 
-
 
NC_013037  Dfer_5176  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  39.31 
 
 
1404 aa  571  1e-161  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.190634 
 
 
-
 
NC_011145  AnaeK_0372  signal transduction histidine kinase with CheB and CheR activity  40.14 
 
 
1233 aa  566  1e-160  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_3165  signal transduction histidine kinase with CheB and CheR activity  39.46 
 
 
1306 aa  565  1e-160  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_013205  Aaci_0673  signal transduction histidine kinase with CheB and CheR activity  36.43 
 
 
1215 aa  563  1.0000000000000001e-159  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_011004  Rpal_3739  MCP methyltransferase, CheR-type  40.87 
 
 
1045 aa  559  1e-158  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_008789  Hhal_0370  protein-glutamate O-methyltransferase  47.79 
 
 
639 aa  558  1e-157  Halorhodospira halophila SL1  Bacteria  normal  0.181962  n/a   
 
 
-
 
NC_010510  Mrad2831_6264  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  42.82 
 
 
1163 aa  553  1e-156  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_007955  Mbur_0399  MCP methyltransferase, CheR-type  37.42 
 
 
820 aa  555  1e-156  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_010511  M446_6211  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  42.48 
 
 
1061 aa  550  1e-155  Methylobacterium sp. 4-46  Bacteria  normal  0.820077  normal  0.703655 
 
 
-
 
NC_010725  Mpop_0310  MCP methyltransferase, CheR-type  38.81 
 
 
1149 aa  546  1e-154  Methylobacterium populi BJ001  Bacteria  normal  0.512157  normal 
 
 
-
 
NC_013440  Hoch_3250  signal transduction histidine kinase with CheB and CheR activity  37.54 
 
 
1348 aa  544  1e-153  Haliangium ochraceum DSM 14365  Bacteria  normal  0.534329  normal  0.0270765 
 
 
-
 
NC_011894  Mnod_3755  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  39.45 
 
 
1063 aa  541  9.999999999999999e-153  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_3046  hypothetical protein  37.46 
 
 
1010 aa  542  9.999999999999999e-153  Saccharophagus degradans 2-40  Bacteria  normal  hitchhiker  0.00164382 
 
 
-
 
NC_011368  Rleg2_5237  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  38.52 
 
 
1324 aa  535  1e-150  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.395635 
 
 
-
 
NC_010505  Mrad2831_5709  MCP methyltransferase, CheR-type  38.62 
 
 
853 aa  522  1e-146  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.729466 
 
 
-
 
NC_013132  Cpin_7206  signal transduction histidine kinase with CheB and CheR activity  35.45 
 
 
1499 aa  521  1e-146  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal 
 
 
-
 
NC_013061  Phep_3913  PAS sensor protein  35.91 
 
 
1337 aa  516  1.0000000000000001e-145  Pedobacter heparinus DSM 2366  Bacteria  normal  0.290527  normal  0.28306 
 
 
-
 
NC_010505  Mrad2831_4430  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  38.52 
 
 
1158 aa  514  1e-144  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_007493  RSP_2229  methylesterase CheB/methylase CheR  36.91 
 
 
1170 aa  504  1e-141  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  0.840236  n/a   
 
 
-
 
NC_009049  Rsph17029_0905  putative PAS/PAC sensor protein  36.91 
 
 
1170 aa  503  1e-141  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  normal  0.968727 
 
 
-
 
NC_014230  CA2559_12648  Signal Transduction Histidine Kinase (STHK) with CheB and CheRactivity  34.39 
 
 
1200 aa  494  9.999999999999999e-139  Croceibacter atlanticus HTCC2559  Bacteria  normal  n/a   
 
 
-
 
NC_013440  Hoch_5252  signal transduction histidine kinase with CheB and CheR activity  35.75 
 
 
1698 aa  493  9.999999999999999e-139  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_4639  signal transduction histidine kinase with CheB and CheR activity  36.76 
 
 
1453 aa  493  9.999999999999999e-139  Haliangium ochraceum DSM 14365  Bacteria  normal  0.432269  normal 
 
 
-
 
NC_009428  Rsph17025_2264  putative PAS/PAC sensor protein  37.05 
 
 
1165 aa  494  9.999999999999999e-139  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  0.620072  normal  0.0600346 
 
 
-
 
NC_013730  Slin_3102  signal transduction histidine kinase with CheB and CheR activity  36.91 
 
 
1418 aa  488  1e-136  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_3278  signal transduction histidine kinase with CheB and CheR activity  34.88 
 
 
2468 aa  482  1e-134  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.0267066 
 
 
-
 
NC_007953  Bxe_C0521  multi sensor hybrid histidine kinase  37.17 
 
 
1344 aa  475  1e-132  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_1404  signal transduction histidine kinase with CheB and CheR activity  35.99 
 
 
1759 aa  476  1e-132  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_008255  CHU_1237  chemotaxis response regulator (methyltransferase)  34.58 
 
 
1618 aa  470  1.0000000000000001e-131  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  normal 
 
 
-
 
NC_008751  Dvul_2487  signal transduction histidine kinase with CheB and CheR activity  36.78 
 
 
1535 aa  464  1e-129  Desulfovibrio vulgaris DP4  Bacteria  normal  0.162467  normal  0.455724 
 
 
-
 
NC_007952  Bxe_B1520  signal transduction histidine kinase (STHK) with CheB and CheR activity  36.24 
 
 
1303 aa  450  1e-125  Burkholderia xenovorans LB400  Bacteria  normal  0.124967  normal 
 
 
-
 
NC_008044  TM1040_1028  signal transduction histidine kinase with CheB and CheR activity  33.9 
 
 
1248 aa  444  1e-123  Ruegeria sp. TM1040  Bacteria  normal  normal  0.507304 
 
 
-
 
NC_002977  MCA1246  methyltransferase CheR, putative  35.97 
 
 
1378 aa  427  1e-118  Methylococcus capsulatus str. Bath  Bacteria  normal  0.271052  n/a   
 
 
-
 
NC_008576  Mmc1_3390  MCP methyltransferase, CheR-type  39.65 
 
 
617 aa  422  1e-116  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_008044  TM1040_0460  MCP methyltransferase, CheR-type  34.69 
 
 
837 aa  407  1.0000000000000001e-112  Ruegeria sp. TM1040  Bacteria  normal  0.604812  normal 
 
 
-
 
NC_010508  Bcenmc03_1302  signal transduction histidine kinase with CheB and CheR activity  31.78 
 
 
1220 aa  402  9.999999999999999e-111  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.772751 
 
 
-
 
NC_008044  TM1040_2227  MCP methyltransferase, CheR-type  34.51 
 
 
824 aa  401  9.999999999999999e-111  Ruegeria sp. TM1040  Bacteria  normal  normal 
 
 
-
 
NC_010086  Bmul_4696  signal transduction histidine kinase with CheB and CheR activity  31.96 
 
 
1214 aa  397  1e-109  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_009622  Smed_6341  putative PAS/PAC sensor protein  41.65 
 
 
629 aa  398  1e-109  Sinorhizobium medicae WSM419  Bacteria  normal  0.433344  normal  0.230755 
 
 
-
 
NC_007802  Jann_2564  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  32.62 
 
 
1089 aa  394  1e-108  Jannaschia sp. CCS1  Bacteria  normal  normal 
 
 
-
 
NC_010623  Bphy_5175  MCP methyltransferase, CheR-type  31.1 
 
 
823 aa  368  1e-100  Burkholderia phymatum STM815  Bacteria  normal  normal  0.367936 
 
 
-
 
NC_010814  Glov_2975  diguanylate cyclase with PAS/PAC sensor  36.39 
 
 
1084 aa  366  1e-99  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007348  Reut_B5191  CheB methylesterase:MCP methyltransferase, CheR-type  31.03 
 
 
813 aa  364  5.0000000000000005e-99  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_0566  MCP methyltransferase, CheR-type with PAS/PAC sensor  35.69 
 
 
1193 aa  363  7.0000000000000005e-99  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_1989  MCP methyltransferase, CheR-type with PAS/PAC sensor  36.22 
 
 
1110 aa  358  2.9999999999999997e-97  Spirosoma linguale DSM 74  Bacteria  normal  0.175442  normal  0.013335 
 
 
-
 
NC_007964  Nham_3990  MCP methyltransferase, CheR-type  44.69 
 
 
432 aa  342  1e-92  Nitrobacter hamburgensis X14  Bacteria  normal  n/a   
 
 
-
 
NC_013132  Cpin_3640  MCP methyltransferase, CheR-type with PAS/PAC sensor  36.13 
 
 
1303 aa  313  7.999999999999999e-84  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal  0.581797 
 
 
-
 
NC_010717  PXO_03023  methyltransferase  36.34 
 
 
604 aa  294  5e-78  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.361036  n/a   
 
 
-
 
NC_013440  Hoch_3427  MCP methyltransferase, CheR-type with PAS/PAC sensor  29.38 
 
 
2031 aa  271  2.9999999999999997e-71  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.0889636 
 
 
-
 
NC_014248  Aazo_0227  MCP methyltransferase  31.53 
 
 
631 aa  268  2.9999999999999995e-70  'Nostoc azollae' 0708  Bacteria  normal  0.993793  n/a   
 
 
-
 
NC_011729  PCC7424_0433  MCP methyltransferase, CheR-type with PAS/PAC sensor  32.76 
 
 
618 aa  252  2e-65  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_011884  Cyan7425_3121  MCP methyltransferase, CheR-type with PAS/PAC sensor  31.46 
 
 
617 aa  249  2e-64  Cyanothece sp. PCC 7425  Bacteria  normal  0.0152355  normal  0.805919 
 
 
-
 
NC_009622  Smed_6342  CheB methylesterase  42.27 
 
 
336 aa  208  4e-52  Sinorhizobium medicae WSM419  Bacteria  normal  0.582664  normal  0.191496 
 
 
-
 
NC_008576  Mmc1_3393  putative PAS/PAC sensor protein  38.91 
 
 
545 aa  180  8e-44  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_010718  Nther_1604  MCP methyltransferase, CheR-type  34.66 
 
 
260 aa  160  1e-37  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  0.0143514  unclonable  1.76137e-23 
 
 
-
 
NC_009712  Mboo_1581  protein-glutamate O-methyltransferase  35.06 
 
 
269 aa  157  1e-36  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.175681  normal  0.125652 
 
 
-
 
NC_007796  Mhun_0961  MCP methyltransferase, CheR-type  35.22 
 
 
283 aa  153  2e-35  Methanospirillum hungatei JF-1  Archaea  normal  0.230734  normal  0.936992 
 
 
-
 
NC_011830  Dhaf_4203  MCP methyltransferase, CheR-type  32.93 
 
 
264 aa  153  2e-35  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.0106813  n/a   
 
 
-
 
NC_013730  Slin_1030  MCP methyltransferase, CheR-type  30.85 
 
 
275 aa  152  3e-35  Spirosoma linguale DSM 74  Bacteria  normal  0.206516  normal 
 
 
-
 
NC_013501  Rmar_0777  MCP methyltransferase, CheR-type  34.38 
 
 
297 aa  152  3e-35  Rhodothermus marinus DSM 4252  Bacteria  normal  0.152669  n/a   
 
 
-
 
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