104 decreased-coverage genes were found for selected organism/s



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Locus tag

Gene type

Replicon accession

From

To

Strand

Gene Length

Product

Protein accession

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Organism name

Kingdom

Coverage Plot

PanDaTox homologs

Experimental validation
Bmur_0006  CDS  NC_014150  5465  6406  942  hypothetical protein  YP_003632316  decreased coverage  0.00155614  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0062  CDS  NC_014150  76145  76393  249  sodium pump decarboxylase, gamma subunit  YP_003632372  decreased coverage  5.26498e-24  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0119  CDS  NC_014150  144133  145440  1308  nucleotide sugar dehydrogenase  YP_003632425  decreased coverage  2.7408e-09  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0120  CDS  NC_014150  145561  147420  1860  Methyltransferase type 12  YP_003632426  decreased coverage  5.61606e-08  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0122  CDS  NC_014150  148989  150125  1137  glycosyl transferase family 2  YP_003632428  decreased coverage  1.24856e-07  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0123  CDS  NC_014150  150169  151611  1443  glycosyl transferase family 2  YP_003632429  decreased coverage  1.03201e-07  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0145  CDS  NC_014150  185031  185342  312  Phosphotransferase system, phosphocarrier protein HPr  YP_003632451  decreased coverage  0.000262907  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0146  CDS  NC_014150  185396  186778  1383  Gluconate transporter  YP_003632452  decreased coverage  0.000250826  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0171  CDS  NC_014150  234993  236246  1254  Homoserine dehydrogenase  YP_003632477  decreased coverage  6.07913e-20  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0211  CDS  NC_014150  290039  290554  516  flavodoxin/nitric oxide synthase  YP_003632517  decreased coverage  1.48876e-22  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0212  CDS  NC_014150  290633  291445  813  hydrolase, TatD family  YP_003632518  decreased coverage  1.02285e-16  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0219  CDS  NC_014150  297232  298380  1149  Ankyrin  YP_003632525  decreased coverage  1.41533e-20  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0220  CDS  NC_014150  298546  299376  831  beta-lactamase domain protein  YP_003632526  decreased coverage  1.90359e-21  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0229  CDS  NC_014150  309281  311428  2148  Ankyrin  YP_003632534  decreased coverage  1.40183e-05  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0262  CDS  NC_014150  345896  346327  432  periplasmic protein  YP_003632567  decreased coverage  4.83026e-14  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0299  CDS  NC_014150  390534  391727  1194  hypothetical protein  YP_003632603  decreased coverage  1.02867e-11  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0338  CDS  NC_014150  429432  429848  417  hypothetical protein  YP_003632641  decreased coverage  3.09697e-09  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0346  CDS  NC_014150  437317  439137  1821  methyl-accepting chemotaxis sensory transducer with Cache sensor  YP_003632649  decreased coverage  5.41258e-05  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0515  CDS  NC_014150  631947  632663  717  hypothetical protein  YP_003632817  decreased coverage  4.94443e-11  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0686  CDS  NC_014150  818238  820121  1884  PTS modulated transcriptional regulator, MtlR family  YP_003632985  decreased coverage  0.00026813  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0687  CDS  NC_014150  820135  820404  270  Phosphotransferase system, phosphocarrier protein HPr  YP_003632986  decreased coverage  0.00126106  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0703  CDS  NC_014150  836077  837123  1047  glycosyl transferase family 2  YP_003633001  decreased coverage  6.39468e-16  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0704  CDS  NC_014150  837139  838134  996  glycosyl transferase family 8  YP_003633002  decreased coverage  2.24419e-15  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0759  CDS  NC_014150  906514  907434  921  binding-protein-dependent transport systems inner membrane component  YP_003633057  decreased coverage  9.61636e-11  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0790  CDS  NC_014150  940129  941487  1359  Gluconate transporter  YP_003633088  decreased coverage  1.65446e-19  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0810  CDS  NC_014150  963267  964211  945  alpha/beta hydrolase fold protein  YP_003633108  decreased coverage  4.84628e-10  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0839  CDS  NC_014150  996782  997093  312  ribosomal protein L21  YP_003633137  decreased coverage  1.0819e-20  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0840  CDS  NC_014150  997093  997449  357  protein of unknown function DUF464  YP_003633138  decreased coverage  8.58523e-22  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0863  CDS  NC_014150  1026039  1026611  573  RNA polymerase, sigma-24 subunit, ECF subfamily  YP_003633161  decreased coverage  4.44823e-21  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0892  CDS  NC_014150  1053160  1054152  993  Squalene/phytoene synthase  YP_003633190  decreased coverage  1.00627e-15  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0910  CDS  NC_014150  1072538  1073011  474  hypothetical protein  YP_003633206  decreased coverage  0.000744586  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0943  CDS  NC_014150  1109127  1111391  2265  lipoprotein  YP_003633238  decreased coverage  2.09151e-06  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0951  CDS  NC_014150  1120951  1123176  2226  glycoside hydrolase family 2 TIM barrel  YP_003633246  decreased coverage  2.87628e-16  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_0982  CDS  NC_014150  1151188  1152777  1590  protein of unknown function DUF262  YP_003633277  decreased coverage  0.000289357  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1087  CDS  NC_014150  1276882  1279269  2388  glycosyl transferase family 51  YP_003633381  decreased coverage  3.66831e-08  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1092  CDS  NC_014150  1285945  1286304  360  ribosomal protein S16  YP_003633386  decreased coverage  1.61695e-15  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1093  CDS  NC_014150  1286337  1286579  243  R-binding protein (contains KH domain)  YP_003633387  decreased coverage  5.71907e-16  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1123  CDS  NC_014150  1317771  1318271  501  protein of unknown function DUF400  YP_003633417  decreased coverage  0.000168699  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1124  CDS  NC_014150  1318480  1318974  495  protein of unknown function DUF400  YP_003633418  decreased coverage  0.00213044  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1145  CDS  NC_014150  1342734  1343612  879  NAD-dependent epimerase/dehydratase  YP_003633439  decreased coverage  1.35991e-05  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1187  CDS  NC_014150  1380210  1380746  537  hypothetical protein  YP_003633480  decreased coverage  2.86291e-09  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1188  CDS  NC_014150  1380788  1380991  204  hypothetical protein  YP_003633481  decreased coverage  1.08523e-08  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1284  CDS  NC_014150  1489447  1492500  3054  TPR repeat-containing protein  YP_003633575  decreased coverage  4.96728e-06  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1292  CDS  NC_014150  1498265  1500148  1884  hypothetical protein  YP_003633583  decreased coverage  1.354e-07  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1319  CDS  NC_014150  1525041  1525169  129  hypothetical protein  YP_003633608  decreased coverage  1.2725e-21  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1337  CDS  NC_014150  1535463  1536572  1110  alanine racemase  YP_003633626  decreased coverage  1.00581e-13  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1352  CDS  NC_014150  1556003  1558186  2184  protein of unknown function DUF262  YP_003633641  decreased coverage  1.70725e-13  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1396  CDS  NC_014150  1601174  1601836  663  CoA-binding domain protein  YP_003633685  decreased coverage  5.87659e-14  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1419  CDS  NC_014150  1622722  1624608  1887  methyl-accepting chemotaxis sensory transducer  YP_003633708  decreased coverage  1.14241e-15  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1470  CDS  NC_014150  1674978  1676576  1599  hypothetical protein  YP_003633756  decreased coverage  1.28381e-14  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1484  CDS  NC_014150  1688506  1690269  1764  aspartyl-tRNA synthetase  YP_003633770  decreased coverage  1.04576e-17  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1495  CDS  NC_014150  1705829  1706941  1113  serpulina hyodysenteriae variable surface protein  YP_003633781  decreased coverage  5.58355e-12  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1527  CDS  NC_014150  1742288  1744228  1941  fructose-16-bisphosphatase  YP_003633813  decreased coverage  1.53829e-15  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1557  CDS  NC_014150  1784347  1784739  393  hypothetical protein  YP_003633843  decreased coverage  1.36189e-22  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1597  CDS  NC_014150  1833673  1835055  1383  MATE efflux family protein  YP_003633883  decreased coverage  3.36267e-19  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1628  CDS  NC_014150  1872626  1873558  933  hypothetical protein  YP_003633913  decreased coverage  6.97711e-21  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1669  CDS  NC_014150  1927210  1929681  2472  metal dependent phosphohydrolase  YP_003633954  decreased coverage  5.1543e-08  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1702  CDS  NC_014150  1960992  1962851  1860  hypothetical protein  YP_003633986  decreased coverage  4.30281e-16  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1704  CDS  NC_014150  1963052  1963999  948  integrase domain protein SAM domain protein  YP_003633988  decreased coverage  1.9221e-19  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1730  CDS  NC_014150  1979644  1979838  195  ribosomal protein L32  YP_003634013  decreased coverage  0.00544421  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1749  CDS  NC_014150  2000555  2001127  573  putative periplasmic protein  YP_003634032  decreased coverage  3.32594e-20  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1822  CDS  NC_014150  2082636  2083979  1344  multi antimicrobial extrusion protein MatE  YP_003634103  decreased coverage  5.55411e-18  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1823  CDS  NC_014150  2084060  2085037  978  cobalamin biosynthesis protein CbiB  YP_003634104  decreased coverage  1.86925e-18  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1824  CDS  NC_014150  2085085  2085669  585  Phosphoglycerate mutase  YP_003634105  decreased coverage  5.87879e-20  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1825  CDS  NC_014150  2086152  2087660  1509  Arylsulfotransferase  YP_003634106  decreased coverage  2.56957e-16  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1826  CDS  NC_014150  2088012  2090408  2397  V-type H(+)-translocating pyrophosphatase  YP_003634107  decreased coverage  1.90573e-15  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1848  CDS  NC_014150  2106292  2106855  564  ribosomal protein L5  YP_003634129  decreased coverage  2.21039e-20  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1849  CDS  NC_014150  2106855  2107040  186  ribosomal protein S14  YP_003634130  decreased coverage  5.94553e-22  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1850  CDS  NC_014150  2107058  2107459  402  ribosomal protein S8  YP_003634131  decreased coverage  3.84535e-21  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1851  CDS  NC_014150  2107481  2108053  573  ribosomal protein L6  YP_003634132  decreased coverage  1.56126e-20  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1882  CDS  NC_014150  2133388  2135835  2448  Nucleotide binding protein PINc  YP_003634162  decreased coverage  6.4311e-14  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1900  CDS  NC_014150  2164099  2164413  315  transcriptional regulator, XRE family  YP_003634178  decreased coverage  1.43236e-17  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1951  CDS  NC_014150  2225289  2225465  177  ribosomal protein L33  YP_003634228  decreased coverage  1.59206e-07  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_1970  CDS  NC_014150  2248234  2249697  1464  integral outer membrane protein TolC, efflux pump component  YP_003634247  decreased coverage  1.88791e-14  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2042  CDS  NC_014150  2325686  2326558  873  hypothetical protein  YP_003634318  decreased coverage  1.25822e-07  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2065  CDS  NC_014150  2348027  2348908  882  L-serine dehydratase, iron-sulfur-dependent, alpha subunit  YP_003634339  decreased coverage  1.67711e-13  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2079  CDS  NC_014150  2363144  2363866  723  hypothetical protein  YP_003634353  decreased coverage  9.12839e-16  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2113  CDS  NC_014150  2402734  2403798  1065  basic membrane lipoprotein  YP_003634387  decreased coverage  1.07207e-16  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2153  CDS  NC_014150  2445616  2446290  675  ABC transporter related protein  YP_003634427  decreased coverage  8.56593e-05  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2163  CDS  NC_014150  2456355  2457461  1107  hypothetical protein  YP_003634437  decreased coverage  2.93461e-20  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2175  CDS  NC_014150  2471028  2472503  1476  membrane bound O-acyl transferase MBOAT family protein  YP_003634448  decreased coverage  4.2797e-05  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2210  CDS  NC_014150  2513552  2514142  591  putative lipoprotein  YP_003634483  decreased coverage  2.34391e-05  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2229  CDS  NC_014150  2533015  2533539  525  hypothetical protein  YP_003634502  decreased coverage  2.96622e-14  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2230  CDS  NC_014150  2533574  2535241  1668  carbon starvation protein CstA  YP_003634503  decreased coverage  1.06566e-11  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2237  CDS  NC_014150  2544319  2544777  459  hypothetical protein  YP_003634510  decreased coverage  0.000464018  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2251  CDS  NC_014150  2561074  2561565  492  hypothetical protein  YP_003634524  decreased coverage  3.19984e-05  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2278  CDS  NC_014150  2585677  2587536  1860  hypothetical protein  YP_003634550  decreased coverage  6.43432e-16  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2333  CDS  NC_014150  2641030  2642091  1062  3-dehydroquinate synthase  YP_003634604  decreased coverage  2.72884e-05  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2382  CDS  NC_014150  2691971  2693716  1746  Protein-disulfide reductase  YP_003634653  decreased coverage  7.87092e-18  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2414  CDS  NC_014150  2721579  2723510  1932  hypothetical protein  YP_003634683  decreased coverage  0.00418212  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2433  CDS  NC_014150  2747329  2748414  1086  serpulina hyodysenteriae variable surface protein  YP_003634702  decreased coverage  7.51611e-09  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2442  CDS  NC_014150  2755874  2758243  2370  lipoprotein  YP_003634711  decreased coverage  5.31268e-14  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2481  CDS  NC_014150  2801262  2802437  1176  Ankyrin  YP_003634750  decreased coverage  2.29526e-12  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2545  CDS  NC_014150  2873882  2874469  588  hypothetical protein  YP_003634813  decreased coverage  1.94345e-22  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2584  CDS  NC_014150  2921299  2922267  969  protein of unknown function DUF534  YP_003634852  decreased coverage  3.78214e-19  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2610  CDS  NC_014150  2952709  2953908  1200  aminotransferase class I and II  YP_003634878  decreased coverage  2.63591e-17  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2691  CDS  NC_014150  3051073  3053643  2571  hypothetical protein  YP_003634957  decreased coverage  7.53337e-08  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2733  CDS  NC_014150  3103001  3103816  816  ribosomal protein S2  YP_003634999  decreased coverage  3.36757e-18  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2744  CDS  NC_014150  3117269  3118615  1347  Lytic transglycosylase catalytic  YP_003635010  decreased coverage  6.42143e-16  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
Bmur_2765  CDS  NC_014150  3140309  3142609  2301  glycoside hydrolase family 57  YP_003635031  decreased coverage  1.29952e-09  n/a    Brachyspira murdochii DSM 12563  Bacteria 
 
 
-
 
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