273 decreased-coverage genes were found for selected organism/s



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Locus tag

Gene type

Replicon accession

From

To

Strand

Gene Length

Product

Protein accession

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Organism name

Kingdom

Coverage Plot

PanDaTox homologs

Experimental validation
Tcur_0963  CDS  NC_013510  1094997  1095185  189  hypothetical protein  YP_003298587  decreased coverage  0.00408343  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_0964  CDS  NC_013510  1095182  1095877  696  hypothetical protein  YP_003298588  decreased coverage  0.0063713  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1107  CDS  NC_013510  1264602  1266455  1854  GTP-binding protein TypA  YP_003298730  decreased coverage  0.00406487  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1146  CDS  NC_013510  1310362  1311255  894  Enoyl-CoA hydratase/isomerase  YP_003298769  decreased coverage  0.00156943  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1165  CDS  NC_013510  1326095  1326715  621  hypothetical protein  YP_003298786  decreased coverage  0.00515508  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1168  CDS  NC_013510  1328246  1328680  435  hypothetical protein  YP_003298789  decreased coverage  0.00652915  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1180  CDS  NC_013510  1337064  1338521  1458  Leucyl aminopeptidase  YP_003298801  decreased coverage  0.00746121  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1201  CDS  NC_013510  1358679  1359068  390  hypothetical protein  YP_003298822  decreased coverage  0.00350086  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1288  CDS  NC_013510  1467920  1469425  1506  cobyric acid synthase CobQ  YP_003298909  decreased coverage  0.00711481  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1306  CDS  NC_013510  1487032  1487640  609  putative anti-sigma regulatory factor, serine/threonine protein kinase  YP_003298927  decreased coverage  0.00486516  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1337  CDS  NC_013510  1521559  1522155  597  GCN5-related N-acetyltransferase  YP_003298957  decreased coverage  0.00907824  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1338  CDS  NC_013510  1522303  1523052  750  Methyltransferase type 11  YP_003298958  decreased coverage  0.00439312  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1349  CDS  NC_013510  1535550  1538102  2553  aminopeptidase N  YP_003298969  decreased coverage  0.000264041  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1363  CDS  NC_013510  1551008  1551526  519  hypothetical protein  YP_003298983  decreased coverage  0.00054435  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1364  CDS  NC_013510  1551666  1553522  1857  glycoside hydrolase family 5  YP_003298984  decreased coverage  0.00194405  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1391  CDS  NC_013510  1582592  1583551  960  hypothetical protein  YP_003299011  decreased coverage  0.000110401  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1448  CDS  NC_013510  1650817  1651311  495  putative anti-sigma regulatory factor, serine/threonine protein kinase  YP_003299065  decreased coverage  0.0047791  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1453  CDS  NC_013510  1654363  1655109  747  ABC transporter related protein  YP_003299070  decreased coverage  0.00421209  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1480  CDS  NC_013510  1688083  1689291  1209  hypothetical protein  YP_003299097  decreased coverage  1.84834e-05  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1506    NC_013510  1726680  1727365  686      decreased coverage  0.000646937  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1516  CDS  NC_013510  1734843  1737365  2523  Tetratricopeptide TPR_4  YP_003299130  decreased coverage  0.00950559  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1531  CDS  NC_013510  1758202  1759479  1278  ATP-dependent Clp protease, ATP-binding subunit ClpX  YP_003299145  decreased coverage  0.00377214  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1534  CDS  NC_013510  1761954  1762814  861  hypothetical protein  YP_003299148  decreased coverage  0.00115723  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1549  CDS  NC_013510  1782191  1783582  1392  GTP-binding protein Obg/CgtA  YP_003299163  decreased coverage  0.0025241  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1550  CDS  NC_013510  1783579  1783689  111  hypothetical protein  YP_003299164  decreased coverage  0.00189068  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1575  CDS  NC_013510  1820097  1820891  795  RNA polymerase II  YP_003299189  decreased coverage  0.00163191  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1576  CDS  NC_013510  1820924  1821586  663  RNA polymerase, sigma-24 subunit, ECF subfamily  YP_003299190  decreased coverage  0.000134885  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1591  CDS  NC_013510  1841669  1842421  753  Ribonuclease H  YP_003299205  decreased coverage  3.06759e-05  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1592  CDS  NC_013510  1842767  1845226  2460  AAA ATPase central domain protein  YP_003299206  decreased coverage  0.00365213  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1612  CDS  NC_013510  1877338  1878696  1359  amino acid permease-associated region  YP_003299226  decreased coverage  0.000949107  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1620  CDS  NC_013510  1886322  1886978  657  ABC transporter related protein  YP_003299234  decreased coverage  0.00145341  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1621  CDS  NC_013510  1887004  1887987  984  transcriptional regulator, MarR family  YP_003299235  decreased coverage  0.00140821  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1628  CDS  NC_013510  1894687  1897152  2466  CoA-binding domain protein  YP_003299242  decreased coverage  0.00866172  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1634  CDS  NC_013510  1903439  1903987  549  RNA polymerase, sigma-24 subunit, ECF subfamily  YP_003299248  decreased coverage  0.000122057  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1652  CDS  NC_013510  1922461  1923582  1122  histidine kinase  YP_003299266  decreased coverage  0.000168648  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1672  CDS  NC_013510  1960254  1961582  1329  transcriptional regulator, XRE family  YP_003299285  decreased coverage  0.000955969  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1673  CDS  NC_013510  1961890  1963026  1137  Phosphoglycerate mutase  YP_003299286  decreased coverage  0.00482153  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1682  CDS  NC_013510  1972297  1973655  1359  FAD-dependent pyridine nucleotide-disulphide oxidoreductase  YP_003299295  decreased coverage  0.000102933  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1695  CDS  NC_013510  1986914  1988155  1242  histidine kinase  YP_003299308  decreased coverage  0.0025241  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1701  CDS  NC_013510  1992584  1995124  2541  tRNA synthetase valyl/leucyl anticodon-binding protein  YP_003299314  decreased coverage  0.000331073  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1723  CDS  NC_013510  2013094  2015655  2562  Bis(5'-nucleosyl)- tetraphosphatase(asymmetrical)  YP_003299335  decreased coverage  7.8095e-05  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1728  CDS  NC_013510  2020556  2021182  627  Lysine exporter protein (LYSE/YGGA)  YP_003299340  decreased coverage  2.59292e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1748  CDS  NC_013510  2047978  2048631  654  transcriptional regulator, PadR-like family  YP_003299360  decreased coverage  2.46986e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1797  CDS  NC_013510  2103362  2103955  594  transcriptional regulator, TetR family  YP_003299409  decreased coverage  0.000197435  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1798  CDS  NC_013510  2104007  2105593  1587  Alkylglycerone-phosphate synthase  YP_003299410  decreased coverage  0.00290405  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1815  CDS  NC_013510  2123016  2123402  387  hypothetical protein  YP_003299427  decreased coverage  1.74188e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1818  CDS  NC_013510  2125697  2128093  2397  ATP-dependent protease La  YP_003299429  decreased coverage  0.000643095  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1819  CDS  NC_013510  2128378  2129409  1032  NAD-dependent epimerase/dehydratase  YP_003299430  decreased coverage  1.10086e-05  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1837  CDS  NC_013510  2151316  2152320  1005  cation diffusion facilitator family transporter  YP_003299448  decreased coverage  2.1737e-08  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1838  CDS  NC_013510  2152320  2152499  180  hypothetical protein  YP_003299449  decreased coverage  1.14085e-08  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1839  CDS  NC_013510  2152496  2152936  441  transcriptional regulator, ArsR family  YP_003299450  decreased coverage  2.60966e-08  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1840  CDS  NC_013510  2153017  2154180  1164  VWA containing CoxE family protein  YP_003299451  decreased coverage  4.54506e-07  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1851  CDS  NC_013510  2168818  2170800  1983  type II secretion system protein  YP_003299462  decreased coverage  0.00122698  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1852  CDS  NC_013510  2170794  2172206  1413  type II secretion system protein E  YP_003299463  decreased coverage  0.00303958  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1860  CDS  NC_013510  2179141  2180349  1209  acetyl-CoA acetyltransferase  YP_003299471  decreased coverage  0.00028581  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1870  CDS  NC_013510  2191994  2194348  2355  hypothetical protein  YP_003299481  decreased coverage  0.000117839  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1871  CDS  NC_013510  2194352  2195584  1233  hypothetical protein  YP_003299482  decreased coverage  8.02358e-07  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1896  CDS  NC_013510  2239734  2240324  591  Exonuclease RNase T and DNA polymerase III  YP_003299504  decreased coverage  0.000163278  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1910  CDS  NC_013510  2250500  2252458  1959  beta-lactamase domain protein  YP_003299517  decreased coverage  2.93974e-05  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1915  CDS  NC_013510  2263972  2266419  2448  SMC domain protein  YP_003299522  decreased coverage  0.00125008  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1930  CDS  NC_013510  2285001  2285810  810  hypothetical protein  YP_003299537  decreased coverage  0.00513575  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1935  CDS  NC_013510  2289318  2289743  426  Glyoxalase/bleomycin resistance protein/dioxygenase  YP_003299542  decreased coverage  0.00196313  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1946  CDS  NC_013510  2300934  2301569  636  hypothetical protein  YP_003299553  decreased coverage  0.00171728  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1960  CDS  NC_013510  2318176  2319861  1686  cytochrome c oxidase, subunit I  YP_003299565  decreased coverage  0.00322963  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1961  CDS  NC_013510  2319968  2320435  468  hypothetical protein  YP_003299566  decreased coverage  0.000972412  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1962  CDS  NC_013510  2320629  2321054  426  OsmC family protein  YP_003299567  decreased coverage  0.000828142  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1976  CDS  NC_013510  2335321  2337279  1959  Carbamoyl-phosphate synthase L chain ATP- binding protein  YP_003299581  decreased coverage  0.000860276  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1977  CDS  NC_013510  2337287  2338891  1605  Methylcrotonoyl-CoA carboxylase  YP_003299582  decreased coverage  6.65967e-05  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1993  CDS  NC_013510  2352499  2353137  639  RNA polymerase, sigma-24 subunit, ECF subfamily  YP_003299598  decreased coverage  2.63841e-09  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_1999  CDS  NC_013510  2361486  2362142  657  protein of unknown function DUF162  YP_003299604  decreased coverage  4.29287e-07  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2010  CDS  NC_013510  2370801  2372366  1566  major facilitator superfamily MFS_1  YP_003299615  decreased coverage  0.00308521  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2022  CDS  NC_013510  2384705  2385703  999  zinc-binding alcohol dehydrogenase family protein  YP_003299627  decreased coverage  4.78739e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2023  CDS  NC_013510  2385919  2387679  1761  von Willebrand factor type A  YP_003299628  decreased coverage  9.27527e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2043  CDS  NC_013510  2404112  2404987  876  UspA domain protein  YP_003299648  decreased coverage  1.73989e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2064  CDS  NC_013510  2426984  2427685  702  Urease accessory protein UreF  YP_003299669  decreased coverage  1.68254e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2065  CDS  NC_013510  2427682  2429403  1722  urease, alpha subunit  YP_003299670  decreased coverage  3.41068e-05  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2072  CDS  NC_013510  2434285  2435544  1260  membrane protein-like protein  YP_003299677  decreased coverage  1.07578e-05  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2073  CDS  NC_013510  2435585  2436619  1035  CHAP domain containing protein  YP_003299678  decreased coverage  2.21932e-05  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2074    NC_013510  2436750  2436989  240      decreased coverage  7.30554e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2084  CDS  NC_013510  2444957  2445802  846  hypothetical protein  YP_003299688  decreased coverage  0.00272631  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2095  CDS  NC_013510  2459280  2461334  2055  threonyl-tRNA synthetase  YP_003299699  decreased coverage  0.00031634  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2096  CDS  NC_013510  2461422  2462063  642  hypothetical protein  YP_003299700  decreased coverage  0.000512388  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2097  CDS  NC_013510  2462060  2462665  606  protein of unknown function DUF322  YP_003299701  decreased coverage  0.000127517  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2099  CDS  NC_013510  2463551  2465710  2160  small GTP-binding protein  YP_003299703  decreased coverage  0.00285281  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2128  CDS  NC_013510  2492988  2494745  1758  aspartyl-tRNA synthetase  YP_003299732  decreased coverage  0.00128349  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2135  CDS  NC_013510  2499134  2501803  2670  alanyl-tRNA synthetase  YP_003299739  decreased coverage  0.00198775  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2155  CDS  NC_013510  2521186  2522121  936  ornithine carbamoyltransferase  YP_003299759  decreased coverage  1.26395e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2177  CDS  NC_013510  2554413  2556611  2199  acyl-CoA dehydrogenase domain protein  YP_003299781  decreased coverage  1.63847e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2178  CDS  NC_013510  2556904  2557365  462  hypothetical protein  YP_003299782  decreased coverage  2.43075e-07  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2179  CDS  NC_013510  2557362  2558237  876  ATPase associated with various cellular activities AAA_5  YP_003299783  decreased coverage  1.02447e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2186  CDS  NC_013510  2565631  2566374  744  hypothetical protein  YP_003299790  decreased coverage  1.43488e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2207  CDS  NC_013510  2588955  2589638  684  GCN5-related N-acetyltransferase  YP_003299811  decreased coverage  1.26395e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2208  CDS  NC_013510  2589635  2590978  1344  6-phosphogluconolactonase  YP_003299812  decreased coverage  9.25433e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2209  CDS  NC_013510  2590975  2591934  960  Glucose-6-P dehydrogenase subunit-like protein  YP_003299813  decreased coverage  2.67002e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2216  CDS  NC_013510  2602207  2603400  1194  membrane protein-like protein  YP_003299820  decreased coverage  1.05763e-05  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2217  CDS  NC_013510  2603417  2604472  1056  cytochrome oxidase assembly  YP_003299821  decreased coverage  8.99528e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2225  CDS  NC_013510  2611919  2613040  1122  FeS assembly protein SufD  YP_003299829  decreased coverage  4.26532e-05  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2226  CDS  NC_013510  2613037  2613381  345  Rieske (2Fe-2S) domain protein  YP_003299830  decreased coverage  4.57155e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2229  CDS  NC_013510  2615548  2616003  456  SUF system FeS assembly protein, NifU family  YP_003299833  decreased coverage  7.71916e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
Tcur_2230  CDS  NC_013510  2616000  2616353  354  protein of unknown function DUF59  YP_003299834  decreased coverage  4.79191e-06  n/a    Thermomonospora curvata DSM 43183  Bacteria 
 
 
-
 
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