140 decreased-coverage genes were found for selected organism/s



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Locus tag

Gene type

Replicon accession

From

To

Strand

Gene Length

Product

Protein accession

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Organism name

Kingdom

Coverage Plot

PanDaTox homologs

Experimental validation
TDE0036  CDS  NC_002967  42225  42617  393  hypothetical protein  NP_970653  decreased coverage  3.98667e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0037  CDS  NC_002967  42641  42889  249  AbrB family transcriptional regulator  NP_970654  decreased coverage  0.000106166  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0094  CDS  NC_002967  112359  112508  150  hypothetical protein  NP_970711  decreased coverage  4.91538e-09  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0108  CDS  NC_002967  128539  128847  309  hypothetical protein  NP_970725  decreased coverage  0.000408837  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0130  CDS  NC_002967  150685  152058  1374  sodium/dicarboxylate symporter family protein  NP_970747  decreased coverage  3.47492e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0134  CDS  NC_002967  153544  155070  1527  oxidoreductase, FAD-dependent  NP_970751  decreased coverage  0.00168414  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0155  CDS  NC_002967  178373  180244  1872  adenylate/guanylate cyclase catalytic domain-containing protein  NP_970772  decreased coverage  0.000541883  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0206  CDS  NC_002967  239761  241617  1857  surface antigen, putative  NP_970822  decreased coverage  0.000122541  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0248  CDS  NC_002967  282208  282576  369  hypothetical protein  NP_970863  decreased coverage  2.42831e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0249  CDS  NC_002967  282679  283242  564  flavoredoxin, putative  NP_970864  decreased coverage  3.03002e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0251  CDS  NC_002967  284807  286186  1380  tryptophanase  NP_970866  decreased coverage  3.6462e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0306  CDS  NC_002967  336880  338709  1830  signal peptide peptidase SppA  NP_970920  decreased coverage  5.32675e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0307  CDS  NC_002967  338795  339700  906  hypothetical protein  NP_970921  decreased coverage  2.81686e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0308  CDS  NC_002967  339727  340776  1050  hypothetical protein  NP_970922  decreased coverage  5.2473e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0312  CDS  NC_002967  343775  345499  1725  TrkH family potassium uptake protein  NP_970926  decreased coverage  0.00568204  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0324  CDS  NC_002967  357584  358204  621  hypothetical protein  NP_970938  decreased coverage  4.0373e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0337  CDS  NC_002967  376385  377197  813  glucosamine-6-phosphate deaminase  NP_970951  decreased coverage  1.49372e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0361  CDS  NC_002967  406129  407502  1374  transporter, putative  NP_970975  decreased coverage  5.37763e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0377  CDS  NC_002967  431975  432067  93  hypothetical protein  NP_970991  decreased coverage  0.00140681  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0386  CDS  NC_002967  437395  438411  1017  ABC transporter, periplasmic substrate-binding protein  NP_971000  decreased coverage  5.51212e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0410  CDS  NC_002967  462193  463059  867  M48 family peptidase  NP_971024  decreased coverage  4.10475e-07  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0412  CDS  NC_002967  465076  466467  1392  hypothetical protein  NP_971026  decreased coverage  0.00252203  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0421  CDS  NC_002967  473556  474842  1287  putative lipoprotein  NP_971035  decreased coverage  0.000214664  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0431  CDS  NC_002967  486560  487684  1125  LysM domain-containing protein  NP_971045  decreased coverage  0.00107019  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0432  CDS  NC_002967  487810  488283  474  TPR domain-containing protein  NP_971046  decreased coverage  0.00201909  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0437  CDS  NC_002967  492226  493695  1470  HEAT repeat-containing PBS lyase  NP_971051  decreased coverage  0.000498384  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0446  CDS  NC_002967  501409  502908  1500  fibronectin type III domain-containing protein  NP_971060  decreased coverage  0.00035766  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0482  CDS  NC_002967  538638  538856  219  hypothetical protein  NP_971096  decreased coverage  1.43386e-08  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0569  CDS  NC_002967  599776  600222  447  hypothetical protein  NP_971183  decreased coverage  0.000273509  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0611  CDS  NC_002967  647369  647479  111  hypothetical protein  NP_971225  decreased coverage  6.00303e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0612  CDS  NC_002967  647457  647561  105  hypothetical protein  NP_971226  decreased coverage  6.05028e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0617  CDS  NC_002967  650183  650317  135  hypothetical protein  NP_971231  decreased coverage  0.000188505  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0618  CDS  NC_002967  650332  650445  114  hypothetical protein  NP_971232  decreased coverage  4.11003e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0619  CDS  NC_002967  650458  652548  2091  methyl-accepting chemotaxis protein  NP_971233  decreased coverage  0.00139031  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0644  CDS  NC_002967  679929  680666  738  ABC transporter, ATP-binding protein  NP_971258  decreased coverage  0.00234663  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0706  CDS  NC_002967  740560  741672  1113  adenine-specific DNA modification methyltransferase  NP_971318  decreased coverage  0.00316388  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0709  CDS  NC_002967  744571  745524  954  bifunctional methionine sulfoxide reductase A/B protein  NP_971321  decreased coverage  0.00161368  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0769  CDS  NC_002967  807774  808058  285  50S ribosomal protein L23  NP_971379  decreased coverage  0.000223701  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0779  CDS  NC_002967  811941  812492  552  50S ribosomal protein L5  NP_971389  decreased coverage  6.63663e-07  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0787  CDS  NC_002967  815208  816524  1317  preprotein translocase subunit SecY  NP_971397  decreased coverage  2.40861e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0788  CDS  NC_002967  816572  816685  114  50S ribosomal protein L36  NP_971398  decreased coverage  2.98686e-07  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0789  CDS  NC_002967  816702  817067  366  30S ribosomal protein S13  NP_971399  decreased coverage  1.54932e-07  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0824  CDS  NC_002967  845316  845966  651  putative lipoprotein  NP_971434  decreased coverage  1.06095e-07  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0833  CDS  NC_002967  853132  854157  1026  putative lipoprotein  NP_971443  decreased coverage  1.10547e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0840  CDS  NC_002967  859509  860984  1476  hypothetical protein  NP_971450  decreased coverage  0.00245278  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0841  CDS  NC_002967  861026  861688  663  hypothetical protein  NP_971451  decreased coverage  0.00182844  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0944  CDS  NC_002967  966387  967097  711  hypothetical protein  NP_971554  decreased coverage  0.00241064  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0970  CDS  NC_002967  994909  995244  336  hypothetical protein  NP_971580  decreased coverage  0.00323179  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0976  CDS  NC_002967  1000166  1000558  393  hypothetical protein  NP_971586  decreased coverage  4.53939e-08  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0977  CDS  NC_002967  1000555  1001700  1146  hypothetical protein  NP_971587  decreased coverage  2.30443e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0987  CDS  NC_002967  1014181  1015137  957  oligopeptide/dipeptide ABC transporter, ATP-binding protein  NP_971596  decreased coverage  0.000207029  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0990  CDS  NC_002967  1017538  1017888  351  hypothetical protein  NP_971599  decreased coverage  2.38527e-07  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0991  CDS  NC_002967  1017964  1018155  192  ribosomal protein L28  NP_971600  decreased coverage  9.39773e-08  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE0992  CDS  NC_002967  1018411  1019100  690  5-formyltetrahydrofolate cyclo-ligase family protein  NP_971601  decreased coverage  1.47922e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1024  CDS  NC_002967  1055715  1057094  1380  hypothetical protein  NP_971632  decreased coverage  9.32144e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1025  CDS  NC_002967  1057241  1057429  189  50S ribosomal protein L32  NP_971633  decreased coverage  1.03246e-08  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1026  CDS  NC_002967  1057442  1057678  237  acyl carrier protein  NP_971634  decreased coverage  1.77026e-08  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1036  CDS  NC_002967  1063945  1064613  669  hypothetical protein  NP_971644  decreased coverage  0.000228622  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1039  CDS  NC_002967  1067212  1068075  864  riboflavin biosynthesis protein, putative  NP_971647  decreased coverage  2.37868e-07  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1040  CDS  NC_002967  1068079  1068348  270  30S ribosomal protein S15  NP_971648  decreased coverage  1.06655e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1054  CDS  NC_002967  1080980  1083058  2079  methyl-accepting chemotaxis protein  NP_971662  decreased coverage  0.00043245  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1102  CDS  NC_002967  1135354  1136265  912  hypothetical protein  NP_971710  decreased coverage  1.83852e-07  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1103  CDS  NC_002967  1136500  1136730  231  hypothetical protein  NP_971711  decreased coverage  4.77452e-09  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1188  CDS  NC_002967  1214664  1216712  2049  NAD(P) transhydrogenase, beta subunit  NP_971796  decreased coverage  0.00625225  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1189    NC_002967  1216709  1218165  1457      decreased coverage  8.21771e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1208  CDS  NC_002967  1240327  1242492  2166  DNA topoisomerase I  NP_971815  decreased coverage  0.000400838  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1262  CDS  NC_002967  1297303  1297422  120  hypothetical protein  NP_971869  decreased coverage  0.00432374  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1269  CDS  NC_002967  1303923  1304612  690  hypothetical protein  NP_971876  decreased coverage  1.12443e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1289  CDS  NC_002967  1327454  1327570  117  hypothetical protein  NP_971896  decreased coverage  5.15815e-09  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1290  CDS  NC_002967  1327539  1328708  1170  hypothetical protein  NP_971897  decreased coverage  1.79937e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1335  CDS  NC_002967  1370956  1372428  1473  alginate O-acetylation protein, putative  NP_971941  decreased coverage  0.000315698  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1483  CDS  NC_002967  1528903  1529127  225  hypothetical protein  NP_972089  decreased coverage  1.29976e-07  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1503  CDS  NC_002967  1551807  1553453  1647  transcription termination factor Rho  NP_972109  decreased coverage  3.7905e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1515  CDS  NC_002967  1562118  1563239  1122  permease domain protein  NP_972121  decreased coverage  0.000964832  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1518  CDS  NC_002967  1564424  1565635  1212  permease, putative  NP_972124  decreased coverage  0.000418137  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1549  CDS  NC_002967  1592280  1592867  588  recombination protein RecR  NP_972155  decreased coverage  0.00118167  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1575  CDS  NC_002967  1622043  1622915  873  lipoyl synthase  NP_972181  decreased coverage  0.00830336  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1664  CDS  NC_002967  1718002  1719042  1041  hypothetical protein  NP_972269  decreased coverage  6.31476e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1679  CDS  NC_002967  1730717  1731139  423  V-type ATP synthase subunit K  NP_972284  decreased coverage  2.6282e-08  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1683  CDS  NC_002967  1734935  1736704  1770  V-type ATP synthase subunit A  NP_972287  decreased coverage  0.00187142  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1685  CDS  NC_002967  1737442  1740405  2964  GGDEF domain-containing protein  NP_972289  decreased coverage  0.00461565  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1717  CDS  NC_002967  1771571  1772221  651  hypothetical protein  NP_972321  decreased coverage  5.35266e-08  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1731  CDS  NC_002967  1785622  1787025  1404  hypothetical protein  NP_972335  decreased coverage  0.00706224  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1739  CDS  NC_002967  1791653  1792717  1065  femAB family protein  NP_972343  decreased coverage  0.00186266  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1774  CDS  NC_002967  1817590  1817979  390  hypothetical protein  NP_972378  decreased coverage  0.000674874  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1776  CDS  NC_002967  1818504  1819322  819  hypothetical protein  NP_972380  decreased coverage  0.000877728  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1781  CDS  NC_002967  1822568  1823350  783  hypothetical protein  NP_972385  decreased coverage  0.000171655  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1813  CDS  NC_002967  1847953  1848339  387  hypothetical protein  NP_972417  decreased coverage  0.00486059  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1864  CDS  NC_002967  1888662  1889198  537  crossover junction endodeoxyribonuclease RuvC  NP_972468  decreased coverage  0.000897484  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1885  CDS  NC_002967  1906997  1907206  210  hypothetical protein  NP_972488  decreased coverage  1.03246e-08  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1886  CDS  NC_002967  1907172  1908578  1407  MiaB-like tRNA modifying enzyme  NP_972489  decreased coverage  8.24769e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1914  CDS  NC_002967  1930979  1932010  1032  Holliday junction DNA helicase RuvB  NP_972517  decreased coverage  0.00218707  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1917  CDS  NC_002967  1934854  1937484  2631  cytidyltransferase-like protein  NP_972520  decreased coverage  0.00878839  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1919  CDS  NC_002967  1938409  1939980  1572  hypothetical protein  NP_972522  decreased coverage  0.00679545  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1941  CDS  NC_002967  1956595  1959375  2781  hypothetical protein  NP_972544  decreased coverage  0.00558858  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE1966  CDS  NC_002967  1980413  1981690  1278  trypsin domain/PDZ domain-containing protein  NP_972569  decreased coverage  4.31561e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE2003  CDS  NC_002967  2022417  2023691  1275  internalin-related protein  NP_972606  decreased coverage  1.99876e-06  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE2006  CDS  NC_002967  2024561  2026930  2370  hypothetical protein  NP_972609  decreased coverage  0.000691446  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE2029  CDS  NC_002967  2057238  2058092  855  TatD family hydrolase  NP_972632  decreased coverage  2.25222e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
TDE2056  CDS  NC_002967  2083949  2085160  1212  outer membrane hemin-binding protein A  NP_972658  decreased coverage  9.93982e-05  n/a    Treponema denticola ATCC 35405  Bacteria 
 
 
-
 
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